ORPHA:99112
Absence of innominate vein
Also known as: Absence of brachiocephalic vein
Clinical definition (Orphanet)
A rare anomaly of the great veins characterized by absence of the left brachiocephalic vein (or innominate vein), resulting in an anomalous venous vasculature. Patients are usually asymptomatic and the anomaly is typically discovered intraoperatively. An association with persistence of left superior vena cava, permanent levoatrial cardinal vein or anomaly of the inferior vena cava has been reported in some cases.
Is anyone studying this?
7
7 papers have ever been indexed under this name. For scale, breast cancer has over 700,000. Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=183) is 38.
7 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 38 (publications denominator n=183).
6 in the last 10 years · high confidence · 24.3th percentile (publications denominator)
Is a treatment being tested?
0
trials for this specific condition
No interventional trial testing a treatment matched this specific condition name on ClinicalTrials.gov (observational studies and pan-disease registries are listed separately when present).
Data as of 26 July 2026
No matched interventional trials. This is true for 59.2% of diseases in the trials denominator (151 of 255). Here are the researchers publishing on it.
high confidence · 29.6th percentile (trials denominator)
Do we know what causes it?
Not yet — the cause hasn't been pinned down in GenCC.
No strong gene–disease assertion joined for this Orphanet entity.
Who's working on it?
36
Distinct author names in 7 sampled papers — named people below.
Who's working on it?
No interventional trial matched this name; these authors publish on it in the sampled literature — a practical starting point for contact.
- 01Awasthy N1 paper · 2013
Associate Consultant, Department of Pediatric and Congenital Heart Diseases, Fortis Escorts Heart Institute, Delhi, India. Electronic address: n_awasthy@yahoo.com.
Papers in Europe PMC - 02Aydin U1 paper · 2019
Cardiovascular Surgery, Pediatric Cardiac Surgery, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Education and Research Hospital, Istanbul, Turkey.
Papers in Europe PMC - 03Babu-Narayan SV1 paper · 2024
Department of Adult Congenital Heart Disease, Royal Brompton Hospital, London, United Kingdom.
Papers in Europe PMC - 04Bansal V1 paper · 2018
Department of Cardiovascular Surgery, Max Super Speciality Hospital, Ghaziabad, Uttar Pradesh, India.
Papers in Europe PMC - 05Bhuvana V1 paper · 2018
Department of Cardiac Anaesthesiology, Max Super Speciality Hospital, Ghaziabad, Uttar Pradesh, India.
Papers in Europe PMC - 06Browne L1 paper · 2024
Department of Radiology, Children's Hospital Colorado, Aurora, CO, USA.
Papers in Europe PMC - 07Darbari A1 paper · 2021
Department of CTVS, All India Institute of Medical Sciences (AIIMS), Rishikesh, Uttarakhand, India.
Papers in Europe PMC - 08Das J1 paper · 2019
Department of Nuclear Medicine and PET-CT, Tata Medical Center, Kolkata, West Bengal, India.
Papers in Europe PMC - 09Ghosh J1 paper · 2019
Department of Medical Oncology Tata Medical Center, Kolkata, West Bengal, India.
Papers in Europe PMC - 10Grosse-Wortmann L1 paper · 2024
Doernbecher Children's Hospital, Department of Pediatrics, Oregon Health and Science University, Portland, Oregon, USA. Electronic address: grossewo@ohsu.edu.
Papers in Europe PMC
Recruiting interventional trials
Trials testing a treatment from the matched ClinicalTrials.gov set
No interventional trial testing a treatment was found for this specific condition name on ClinicalTrials.gov.
See who's working on it above — people publishing on this disease are often the practical next contact when no trial is listed.
Where to find support
We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:
India — NPRD
Last verified 2026-07-26This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.
Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.
How we counted this
Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored below but are not added to the query string.
"Absence of innominate vein" OR "Absence of brachiocephalic vein"
ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):
"Absence of innominate vein" OR "Absence of the innominate vein" OR "Absence of brachiocephalic vein" OR "Absence of the brachiocephalic vein"
Study-type breakdown: 0 interventional · 0 observational · 0 expanded access. Only interventional studies enter the trial headline.
Cross-references (from Mondo): UMLS:C4707656
Query health: ok — strategies attempted: phrase; with hits: phrase
Run this search on ClinicalTrials.gov
Confidence reasoning
- Preferred label is multi-word and distinctive
- No synonyms dropped by stoplist
- No label/synonym collisions with other diseases in this corpus