ORPHA:98918
Acute motor axonal neuropathy
Also known as: AMAN · Acute pure motor GBS · Acute pure motor Guillain-Barré syndrome
Publications
1,905
Trials
0
Interventional, condition-specific
Researchers
959
Distinct authors in sample
Gene link
—
Readiness
1/6
Stages with a signal
Clinical definition (Orphanet)
A rare pure motor axonal form of Guillain-Barré syndrome (GBS).
Cross-references
Joined from Mondo / Orphanet. MeSH labels may enter searches; UMLS / OMIM / NCIT are stored for reference.
- MONDO:0020349
- UMLS:C3890941
- NCIT:C116929
Additional Mondo synonyms (3)
acute pure motor GBS · acute pure motor Guillain-Barre syndrome · acute pure motor Guillain-Barré syndrome
Research stages
Trial readiness signals
Where this condition sits on an open-data research pipeline — not how close a treatment is, and not medical advice. Empty stages often mean “not in these databases under this Mondo ID,” not “impossible.”
1/6 stages with a signal
Research-stage checklist from open sources (GenCC, literature, Monarch when enriched, ClinicalTrials.gov). Not a prognosis or care recommendation.
- Gene identifiedNot found
No GenCC disease–gene assertion in this build
- LiteraturePresent
1,905 matched papers (1,333 in last 10 years) Source
- Phenotype characterisedNot checked
Not yet enriched from Monarch / HPO
- Animal modelNot checked
Not yet enriched from Monarch / Alliance
- Orphan designationNot checked
FDA/EMA orphan-drug designation not enriched yet
- Interventional trialNot found
No matched interventional trial under our ClinicalTrials.gov rules
Biology
Genes and phenotypes
Gene–disease validity from GenCC, plus phenotypes and animal models joined from Monarch Initiative via Mondo ID — not a clinical diagnosis aid.
Do we know what causes it?
Not yet — the cause hasn't been pinned down in GenCC.
No strong gene–disease assertion joined for this Orphanet entity.
Phenotypes (Monarch / HPO)
Not enriched in this build — Monarch phenotype joins were not run for this record.
Animal models (Monarch / Alliance)
Not enriched in this build.
Literature
Is anyone studying this?
1,905
1,905 papers have been published on this condition. That is a real research literature — still far smaller than common diseases (breast cancer: over 700,000 papers). Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=5449) is 41.
1,905 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 41 (publications denominator n=5449).
1,333 in the last 10 years · low confidence
Phrase hits: 1,905 · MeSH hits: 0
Who's working on it?
959
Distinct author names in 200 sampled papers — named people below.
Who's working on it?
No interventional trial matched this name; these authors publish on it in the sampled literature — a practical starting point for contact.
- 01Finsterer J8 papers · 2026
Neurology and Neurophysiology Center, Postfach 20, 1180, Vienna, Austria. fifigs1@yahoo.de.
Papers in Europe PMC - 02Chen R3 papers · 2025
Department of Neurology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, China.
Papers in Europe PMC - 03Hassan AM3 papers · 2026
Department of Internal Medicine,Prince Hamza Hospital, Amman, Jordan.
Papers in Europe PMC - 04Kumar A3 papers · 2026
General Medicine, Maulana Azad Medical College, New Delhi, IND.
Papers in Europe PMC - 05Li X3 papers · 2026
Department of Clinical Diagnosis, Laboratory of Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Papers in Europe PMC - 06Liu Y3 papers · 2026
Department of Neurology, Huangshi Central Hospital, Hubei Polytechnic University, Huangshi, Hubei, 435000, People's Republic of China.
Papers in Europe PMC - 07Wang X3 papers · 2026
Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Papers in Europe PMC - 08Wang Y3 papers · 2025
Department of Neurology, Affiliated Hospital of Jining Medical University, Jining, Shandong 272029, China.
Papers in Europe PMC - 09Yang X3 papers · 2026
Department of Neurology, the First People's Hospital of Tianmen, Affiliated Hospital of Hubei University of Science and Technology, Tianmen, Hubei, 431701, People's Republic of China.
Papers in Europe PMC - 10Ahmed J2 papers · 2025
Laboratory of Gut-Brain Axis, Infectious Diseases Division, icddr,b, Dhaka, Bangladesh.
Papers in Europe PMC
Clinical research
Is a treatment being tested?
0
interventional trials for this specific condition
No interventional trial testing a treatment matched this specific condition name on ClinicalTrials.gov (observational studies and pan-disease registries are listed separately when present).
Data as of 27 July 2026
No matched interventional trials. This is true for 73% of diseases in the trials denominator (5114 of 7003). Here are the researchers publishing on it.
low confidence · 36.5th percentile (trials denominator)
Recruiting interventional trials
From the matched ClinicalTrials.gov set
No interventional trial testing a treatment was found for this specific condition name on ClinicalTrials.gov.
See who's working on it — people publishing on this disease are often the practical next contact when no trial is listed.
Where to find support
We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:
India — NPRD
Last verified 2026-07-26This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.
Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.
How we counted this
Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored on the overview but are not added to the query string.
"Acute motor axonal neuropathy" OR "Acute pure motor GBS" OR "Acute pure motor Guillain-Barré syndrome" OR "acute pure motor Guillain-Barre syndrome"
ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):
"Acute motor axonal neuropathy" OR "Acute pure motor GBS" OR "Acute pure motor Guillain-Barré syndrome" OR "acute pure motor Guillain-Barre syndrome"
Study-type breakdown: 0 interventional · 0 observational · 0 expanded access. Only interventional studies enter the trial headline.
Query health: ok — strategies attempted: phrase; with hits: phrase
Run this search on ClinicalTrials.gov
Synonyms dropped by stoplist: AMAN
Confidence reasoning
- Preferred label is multi-word and distinctive
- 1 synonym(s) dropped by stoplist (may under-count)
- No label/synonym collisions with other diseases in this corpus
- Publication count (1905) is extremely high with unknown/missing prevalence — treat as possible over-matching, not proven research intensity
Ingested 2026-07-27T05:43:42.358Z