ORPHA:98844
Classic Hodgkin lymphoma, mixed cellularity type
How rare: 1-9 / 1 000 000 — roughly one to nine people per million. In a city the size of Kolkata, perhaps a few dozen.
Is anyone studying this?
681
681 papers have been published on this condition. That is a real research literature — still far smaller than common diseases (breast cancer: over 700,000 papers). Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=183) is 38.
681 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 38 (publications denominator n=183).
302 in the last 10 years · medium confidence · 85th percentile (publications denominator)
Is a treatment being tested?
15
trials for this specific condition
15 interventional trials matched this specific condition name; none in our sample are currently recruiting. 43 trials are registered for classic Hodgkin lymphoma, the broader category — shown separately because they may or may not enrol this specific subtype.
Data as of 26 July 2026
43
trials for classic Hodgkin lymphoma, the broader category this belongs to
Trials registered for a broader category may or may not enrol people with this specific subtype — eligibility criteria vary, and the trial record often doesn't say. Worth raising with a clinician. How we count trials.
15 interventional trials — more than 59.2% of diseases in the trials denominator have none at all (151 of 255; this disease is at the 88.4th percentile).
medium confidence · 88.4th percentile (trials denominator)
Do we know what causes it?
Not yet — the cause hasn't been pinned down in GenCC.
No strong gene–disease assertion joined for this Orphanet entity.
Who's working on it?
1,306
Distinct author names in 200 sampled papers — named people below.
Who's working on it?
People publishing on this condition (sampled Europe PMC records). Affiliation is the most recent found in that sample.
- 01Hansmann ML5 papers · 2026
Consultation and reference center for lymph node pathology at Dr. Senckenberg Institute of Pathology, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany.
Papers in Europe PMC - 02Nakamura S5 papers · 2023
Department of Pathology and Laboratory Medicine, Nagoya University Hospital, Nagoya, Japan.
Papers in Europe PMC - 03Satou A5 papers · 2023
Department of Surgical Pathology, Aichi Medical University Hospital, Nagakute, Japan.
Papers in Europe PMC - 04Hartmann S4 papers · 2026
Dr. Senckenberg Institute of Pathology, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany.
Papers in Europe PMC - 05Jaffe ES4 papers · 2026
From the Hematopathology Section, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Papers in Europe PMC - 06Schäfer H4 papers · 2026
Molecular Bioinformatics, Institute of Computer Science, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany.
Papers in Europe PMC - 07Scharf S4 papers · 2026
Department of Molecular Bioinformatics, Institute of Computer Science, Johann Wolfgang Goethe-University, Frankfurt/Main, Hessen, Germany; Frankfurt Institute for Advanced Studies (FIAS), Frankfurt/Main, Hessen, Germany.
Papers in Europe PMC - 08Takahara T4 papers · 2023
Department of Surgical Pathology, Aichi Medical University Hospital, Nagakute, Japan.
Papers in Europe PMC - 09Wang Y4 papers · 2024
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Papers in Europe PMC - 10Wurzel P4 papers · 2026
Department of Molecular Bioinformatics, Institute of Computer Science, Johann Wolfgang Goethe-University, Frankfurt/Main, Hessen, Germany; Frankfurt Institute for Advanced Studies (FIAS), Frankfurt/Main, Hessen, Germany.
Papers in Europe PMC
Recruiting interventional trials
Trials testing a treatment from the matched ClinicalTrials.gov set
15 interventional trials matched after quoted-phrase search and title/condition post-filter.
No currently recruiting studies in the matched set. Open the same search on ClinicalTrials.gov.
Where to find support
We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:
India — NPRD
Last verified 2026-07-26This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.
Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.
How we counted this
Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored below but are not added to the query string.
"Classic Hodgkin lymphoma, mixed cellularity type" OR "Hodgkin lymphoma, mixed cellularity" OR "Hodgkin's disease mixed cellularity" OR "Hodgkin's disease, mixed cellularity of unspecified site" OR "Hodgkin's lymphoma mixed cellularity" OR "MCCHL" OR "Mixed cellularity Classic Hodgkin lymphoma" OR "mixed cellularity Hodgkin lymphoma" OR "mixed cellularity Hodgkin's disease" OR "mixed cellularity Hodgkin's lymphoma" OR "mixed cellularity classical Hodgkin lymphoma"
ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):
"Classic Hodgkin lymphoma, mixed cellularity type" OR "Hodgkin lymphoma, mixed cellularity" OR "Hodgkin's disease mixed cellularity" OR "Hodgkin's disease, mixed cellularity of unspecified site" OR "Hodgkin's disease, mixed cellularity of the unspecified site" OR "Hodgkin's lymphoma mixed cellularity" OR "MCCHL" OR "Mixed cellularity Classic Hodgkin lymphoma" OR "mixed cellularity Hodgkin lymphoma" OR "mixed cellularity Hodgkin's disease" OR "mixed cellularity Hodgkin's lymphoma" OR "mixed cellularity classical Hodgkin lymphoma"
Interventional trials matched via: phrase (mesh = registered under a MeSH descriptor no name phrase would catch; recall-expansion = gene / selected parent terms used only for trials).
Study-type breakdown: 15 interventional · 0 observational · 0 expanded access. Only interventional studies enter the trial headline.
Cross-references (from Mondo): UMLS:C0152266 NCIT:C3517
Query health: ok — strategies attempted: phrase; with hits: phrase
Run this search on ClinicalTrials.gov
Synonyms dropped by stoplist: MCHL
Confidence reasoning
- Preferred label is multi-word and distinctive
- 1 synonym(s) dropped by stoplist (may under-count)
- No label/synonym collisions with other diseases in this corpus