ORPHA:98816
Childhood occipital visual epilepsy
Also known as: COVE · Idiopathic chilldhood occipital epilepsy-Gastaut type · Late-onset benign childhood occipital epilepsy
Query health: suspect — Only one of 2 strategies returned hits (phrase).
Publications
54
50.1th percentile
Trials
0
Interventional, condition-specific
Researchers
312
Distinct authors in sample
Gene link
—
Readiness
1/6
Stages with a signal
Clinical definition (Orphanet)
A form of rare self-limited childhood occipital characterized by originating in the occipital lobe, often present with visual phenomena, occurring around 7-16 years. are typically characterized by sensory visual symptoms with elementary visual phenomena, such as flashing lights, visual distortions, eye deviation, or temporary blindness. Secondary generalized may also occur. The severity and the frequency of the vary among the patients.
Cross-references
Joined from Mondo / Orphanet. MeSH labels may enter searches; UMLS / OMIM / NCIT are stored for reference.
- MONDO:0020308
- UMLS:C0393677
Additional Mondo synonyms (3)
benign childhood occipital epilepsy, Gastaut type · childhood occipital epilepsy (Gastaut type) · late-onset benign childhood occipital epilepsy
Research stages
Trial readiness signals
Where this condition sits on an open-data research pipeline — not how close a treatment is, and not medical advice. Empty stages often mean “not in these databases under this Mondo ID,” not “impossible.”
1/6 stages with a signal
Research-stage checklist from open sources (GenCC, literature, Monarch when enriched, ClinicalTrials.gov). Not a prognosis or care recommendation.
- Gene identifiedNot found
No GenCC disease–gene assertion in this build
- LiteraturePresent
54 matched papers (41 in last 10 years) Source
- Phenotype characterisedNot checked
Not yet enriched from Monarch / HPO
- Animal modelNot checked
Not yet enriched from Monarch / Alliance
- Orphan designationNot checked
FDA/EMA orphan-drug designation not enriched yet
- Interventional trialNot found
No matched interventional trial under our ClinicalTrials.gov rules
Biology
Genes and phenotypes
Gene–disease validity from GenCC, plus phenotypes and animal models joined from Monarch Initiative via Mondo ID — not a clinical diagnosis aid.
Do we know what causes it?
Not yet — the cause hasn't been pinned down in GenCC.
No strong gene–disease assertion joined for this Orphanet entity.
Phenotypes (Monarch / HPO)
Not enriched in this build — Monarch phenotype joins were not run for this record.
Animal models (Monarch / Alliance)
Not enriched in this build.
Literature
Is anyone studying this?
54
54 papers have ever been published on this condition (under this name). For scale, breast cancer has over 700,000. Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=5449) is 41.
54 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 41 (publications denominator n=5449).
41 in the last 10 years · medium confidence · 50.1th percentile (publications denominator)
Phrase hits: 54 · MeSH hits: 0
Who's working on it?
312
Distinct author names in 54 sampled papers — named people below.
Who's working on it?
No interventional trial matched this name; these authors publish on it in the sampled literature — a practical starting point for contact.
- 01Parisi P3 papers · 2011
NESMOS Department, Chair of Pediatrics, Child Neurology, Faculty of Medicine and Psychology, Sapienza University, Via di Grottarossa, 1035-1039, Rome,00189, Italy. pasquale.parisi@uniroma1.it
Papers in Europe PMC - 02Aaberg KM2 papers · 2026
National Center for Epilepsy, Division of Clinical Neuroscience, full member of European Reference Network EpiCARE, Oslo University Hospital, Oslo, Norway.
Papers in Europe PMC - 03Balestri P2 papers · 2009Papers in Europe PMC
- 04Brandlistuen RE2 papers · 2026
National Institute for Public Health, Oslo, Norway.
Papers in Europe PMC - 05Cachia P2 papers · 2021
Hospital de Niños Victor J Vilela de Rosario, Santa Fé, Argentina.
Papers in Europe PMC - 06Caraballo RH2 papers · 2021
Buenos AiresHospital Nacional de Pediatría, Buenos Aires, Argentina. rhcaraballo@arnet.com.ar
Papers in Europe PMC - 07Chiarelli F2 papers · 2011Papers in Europe PMC
- 08Chin RF2 papers · 2026
Royal Hospital for Children and Young People, Edinburgh, UK.
Papers in Europe PMC - 09Grosso S2 papers · 2009
Department of Pediatrics, Pediatric Neurology Section, University of Siena, Siena Santa Maria alle Scotte Hospital, Siena, Italy. grosso@unisi.it
Papers in Europe PMC - 10Loddenkemper T2 papers · 2015
Department of Child Neurology, Hospital Sant Joan de Déu, University of Barcelona, Spain.
Papers in Europe PMC
Clinical research
Is a treatment being tested?
0
interventional trials for this specific condition
No interventional trial testing a treatment matched this specific condition name on ClinicalTrials.gov (observational studies and pan-disease registries are listed separately when present).
Data as of 27 July 2026
No matched interventional trials. This is true for 73% of diseases in the trials denominator (5114 of 7003). Here are the researchers publishing on it.
medium confidence · 36.5th percentile (trials denominator)
Recruiting interventional trials
From the matched ClinicalTrials.gov set
No interventional trial testing a treatment was found for this specific condition name on ClinicalTrials.gov.
See who's working on it — people publishing on this disease are often the practical next contact when no trial is listed.
Where to find support
We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:
India — NPRD
Last verified 2026-07-26This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.
Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.
How we counted this
Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored on the overview but are not added to the query string.
"Childhood occipital visual epilepsy" OR "Idiopathic chilldhood occipital epilepsy-Gastaut type" OR "Late-onset benign childhood occipital epilepsy" OR "benign childhood occipital epilepsy, Gastaut type" OR "childhood occipital epilepsy (Gastaut type)"
ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):
"Childhood occipital visual epilepsy" OR "Idiopathic chilldhood occipital epilepsy-Gastaut type" OR "Late-onset benign childhood occipital epilepsy" OR "benign childhood occipital epilepsy, Gastaut type" OR "childhood occipital epilepsy (Gastaut type)" OR "self-limited childhood occipital epilepsy" OR "childhood-onset self-limited focal epilepsy syndrome" OR "childhood-onset epilepsy syndrome"
Recall-expansion terms: self-limited childhood occipital epilepsy, childhood-onset self-limited focal epilepsy syndrome, childhood-onset epilepsy syndrome
Study-type breakdown: 0 interventional · 0 observational · 0 expanded access. Only interventional studies enter the trial headline.
Query health: suspect — strategies attempted: phrase, recall-expansion; with hits: phrase
Run this search on ClinicalTrials.gov
Synonyms dropped by stoplist: COVE
Confidence reasoning
- Preferred label is multi-word and distinctive
- 1 synonym(s) dropped by stoplist (may under-count)
- No label/synonym collisions with other diseases in this corpus
Ingested 2026-07-27T05:26:00.418Z