ORPHA:98812
Paroxysmal hypnogenic dyskinesia
Also known as: Nocturnal paroxysmal dystonia · Paroxysmal hypnagogic dyskinesia · Paroxysmal hypnagogic dystonia · Paroxysmal nocturnal dyskinesia
Is anyone studying this?
191
191 papers have ever been published on this condition (under this name). For scale, breast cancer has over 700,000. Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=183) is 38.
191 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 38 (publications denominator n=183).
70 in the last 10 years · low confidence
Is a treatment being tested?
0
trials for this specific condition
No interventional trial testing a treatment matched this specific condition name on ClinicalTrials.gov (observational studies and pan-disease registries are listed separately when present).
Data as of 26 July 2026
No matched interventional trials. This is true for 59.2% of diseases in the trials denominator (151 of 255). Here are the researchers publishing on it.
low confidence · 29.6th percentile (trials denominator)
Do we know what causes it?
Not yet — the cause hasn't been pinned down in GenCC.
No strong gene–disease assertion joined for this Orphanet entity.
Who's working on it?
759
Distinct author names in 191 sampled papers — named people below.
Who's working on it?
No interventional trial matched this name; these authors publish on it in the sampled literature — a practical starting point for contact.
- 01
- 02
- 03Provini F12 papers · 2025
Neurological Institute, University of Bologna, Bologna, Italy.
Papers in Europe PMC - 04Okada M11 papers · 2026
Department of Neuropsychiatry, Division of Neuroscience, Graduate School of Medicine, Mie University, Tsu, Mie 514-8507, Japan.
Papers in Europe PMC - 05Tinuper P10 papers · 2025
IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
Papers in Europe PMC - 06Nobili L8 papers · 2025
"Claudio Munari" Center for Epilepsy Surgery, Niguarda Hospital, Milan, Italy, lino.nobili@unige.it.
Papers in Europe PMC - 07Bisulli F7 papers · 2025
IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
Papers in Europe PMC - 08
- 09Fukuyama K6 papers · 2020
Department of Neuropsychiatry, Division of Neuroscience, Graduate School of Medicine, Mie University, Tsu, Mie 514-8507, Japan.
Papers in Europe PMC - 10Berkovic SF4 papers · 2025
Epilepsy Research Centre, University of Melbourne (Austin Health), Heidelberg, Victoria, Australia.
Papers in Europe PMC
Recruiting interventional trials
Trials testing a treatment from the matched ClinicalTrials.gov set
No interventional trial testing a treatment was found for this specific condition name on ClinicalTrials.gov.
See who's working on it above — people publishing on this disease are often the practical next contact when no trial is listed.
Where to find support
We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:
India — NPRD
Last verified 2026-07-26This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.
Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.
How we counted this
Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored below but are not added to the query string.
"Paroxysmal hypnogenic dyskinesia" OR "Nocturnal paroxysmal dystonia" OR "Paroxysmal hypnagogic dyskinesia" OR "Paroxysmal hypnagogic dystonia" OR "Paroxysmal nocturnal dyskinesia"
ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):
"Paroxysmal hypnogenic dyskinesia" OR "Nocturnal paroxysmal dystonia" OR "Paroxysmal hypnagogic dyskinesia" OR "Paroxysmal hypnagogic dystonia" OR "Paroxysmal nocturnal dyskinesia"
Study-type breakdown: 0 interventional · 0 observational · 0 expanded access. Only interventional studies enter the trial headline.
0Query health: ok — strategies attempted: phrase; with hits: phrase
Run this search on ClinicalTrials.gov
Confidence reasoning
- Preferred label is multi-word and distinctive
- No synonyms dropped by stoplist
- No label/synonym collisions with other diseases in this corpus
- No Orphanet definition and no Mondo IDs — likely taxonomy scaffolding; confidence capped at low