RARE DISEASERESEARCH ATLAS

ORPHA:90037

Drug-induced autoimmune hemolytic anemia

high confidence

Also known as: Drug-induced AIHA

Query health: suspect — Only one of 2 strategies returned hits (phrase).

Clinical definition (Orphanet)

Drug-induced autoimmune hemolytic anemia is a type of autoimmune hemolytic anemia (AIHA) that occurs as a reaction to therapeutic drugs, and can be due to various mechanisms.

How rare: <1 / 1 000 000 — fewer than one in a million. In a city the size of Kolkata, that might mean on the order of fifteen people.

Orphanet entry

Is anyone studying this?

103

103 papers have ever been published on this condition (under this name). For scale, breast cancer has over 700,000. Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=183) is 38.

103 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 38 (publications denominator n=183).

64 in the last 10 years · high confidence · 60.9th percentile (publications denominator)

Is a treatment being tested?

0

trials for this specific condition

No interventional trial testing a treatment matched this specific condition name on ClinicalTrials.gov (observational studies and pan-disease registries are listed separately when present). 72 trials are registered for autoimmune hemolytic anemia, the broader category — shown separately because they may or may not enrol this specific subtype.

Data as of 26 July 2026

72

trials for autoimmune hemolytic anemia, the broader category this belongs to

Trials registered for a broader category may or may not enrol people with this specific subtype — eligibility criteria vary, and the trial record often doesn't say. Worth raising with a clinician. How we count trials.

No matched interventional trials. This is true for 59.2% of diseases in the trials denominator (151 of 255). Here are the researchers publishing on it.

high confidence · 29.6th percentile (trials denominator)

Do we know what causes it?

Not yet — the cause hasn't been pinned down in GenCC.

No strong gene–disease assertion joined for this Orphanet entity.

Who's working on it?

503

Distinct author names in 103 sampled papers — named people below.

Who's working on it?

No interventional trial matched this name; these authors publish on it in the sampled literature — a practical starting point for contact.

  1. 01
    Barcellini W5 papers · 2024

    U.O. Oncoematologia, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

    Papers in Europe PMC
  2. 02
    Fattizzo B3 papers · 2024

    Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, 20100 Milan, Italy.

    Papers in Europe PMC
  3. 03
    Michel M3 papers · 2019

    Department of Medicine, Henri Mondor Hospital, Université Paris-Est, Assistance Publique Hôpitaux de Paris Creteil, Creteil, France.

    Papers in Europe PMC
  4. 04
    Sharma N3 papers · 2024

    School of Medicine Oakland University Rochester MI USA.

    Papers in Europe PMC
  5. 05
    Berentsen S2 papers · 2024

    Department of Research and Innovation, Haugesund Hospital, P.O. Box 2170, Haugesund, 5504, Norway.

    Papers in Europe PMC
  6. 06
    Hadid T2 papers · 2020

    Van Elslander Cancer Center, 19229 Mack Ave, Suite 23, Grosse Pointe Woods, MI 48236 USA.

    Papers in Europe PMC
  7. 07
    Ito K2 papers · 2026

    Dept. of Pediatric Nephrology, Tokyo Women's Medical College.

    Papers in Europe PMC
  8. 08
    Mitrović M2 papers · 2023

    Medical Faculty, University of Belgrade, 11000 Belgrade, Serbia.

    Papers in Europe PMC
  9. 09
    Shen Y2 papers · 2021

    Department of Hematology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, People's Republic of China.

    Papers in Europe PMC
  10. 10
    Sugimoto T2 papers · 2026

    Department of Dermatology, Nippon Medical School Musashikosugi Hospital.

    Papers in Europe PMC

Recruiting interventional trials

Trials testing a treatment from the matched ClinicalTrials.gov set

No interventional trial testing a treatment was found for this specific condition name on ClinicalTrials.gov.

72 interventional trials matched autoimmune hemolytic anemia, the broader category — see the summary above. Those studies are not counted in the condition-specific total.

Where to find support

We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:

India — NPRD

Last verified 2026-07-26

This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.

Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.

How we counted this

Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored below but are not added to the query string.

"Drug-induced autoimmune hemolytic anemia" OR "Drug-induced AIHA"

Run this search on Europe PMC

ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):

"Drug-induced autoimmune hemolytic anemia" OR "Drug-induced AIHA" OR "autoimmune disorder of blood"

Study-type breakdown: 0 interventional · 0 observational · 0 expanded access. Only interventional studies enter the trial headline.

Cross-references (from Mondo): UMLS:C0391817

Query health: suspect — strategies attempted: phrase, recall-expansion; with hits: phrase

Run this search on ClinicalTrials.gov

Confidence reasoning

  • Preferred label is multi-word and distinctive
  • No synonyms dropped by stoplist
  • No label/synonym collisions with other diseases in this corpus

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