ORPHA:90021
Radiation myelitis
Publications
346
69.6th percentile
Trials
0
Interventional, condition-specific
Researchers
1,185
Distinct authors in sample
Gene link
—
Readiness
1/6
Stages with a signal
Clinical definition (Orphanet)
Radiation myelitis is a rare neurological disease characterized by the development of paresthesias, as well as, in severe cases, paresis and paralysis following irradiation of tumors in which the spinal cord is included within the radiation field. Symptoms may develop months or years after radiation therapy was administered.
Cross-references
Joined from Mondo / Orphanet. MeSH labels may enter searches; UMLS / OMIM / NCIT are stored for reference.
- MONDO:0019529
- UMLS:C4706614
Research stages
Trial readiness signals
Where this condition sits on an open-data research pipeline — not how close a treatment is, and not medical advice. Empty stages often mean “not in these databases under this Mondo ID,” not “impossible.”
1/6 stages with a signal
Research-stage checklist from open sources (GenCC, literature, Monarch when enriched, ClinicalTrials.gov). Not a prognosis or care recommendation.
- Gene identifiedNot found
No GenCC disease–gene assertion in this build
- LiteraturePresent
346 matched papers (121 in last 10 years) Source
- Phenotype characterisedNot checked
Not yet enriched from Monarch / HPO
- Animal modelNot checked
Not yet enriched from Monarch / Alliance
- Orphan designationNot checked
FDA/EMA orphan-drug designation not enriched yet
- Interventional trialNot found
No matched interventional trial under our ClinicalTrials.gov rules
Biology
Genes and phenotypes
Gene–disease validity from GenCC, plus phenotypes and animal models joined from Monarch Initiative via Mondo ID — not a clinical diagnosis aid.
Do we know what causes it?
Not yet — the cause hasn't been pinned down in GenCC.
No strong gene–disease assertion joined for this Orphanet entity.
Phenotypes (Monarch / HPO)
Not enriched in this build — Monarch phenotype joins were not run for this record.
Animal models (Monarch / Alliance)
Not enriched in this build.
Literature
Is anyone studying this?
346
346 papers have ever been published on this condition (under this name). For scale, breast cancer has over 700,000. Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=5449) is 41.
346 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 41 (publications denominator n=5449).
121 in the last 10 years · high confidence · 69.6th percentile (publications denominator)
Phrase hits: 346 · MeSH hits: 0
Who's working on it?
1,185
Distinct author names in 200 sampled papers — named people below.
Who's working on it?
No interventional trial matched this name; these authors publish on it in the sampled literature — a practical starting point for contact.
- 01Wang J7 papers · 2023
Department of Radiation Oncology, Peking University Third Hospital, 49 Huayuan North Road, Beijing, 100191, People's Republic of China. junjiewang_edu@sina.cn.
Papers in Europe PMC - 02Sun H6 papers · 2025
Department of Radiation Oncology, Peking University Third Hospital, 49 Huayuan North Road, Beijing, 100191, People's Republic of China.
Papers in Europe PMC - 03Zhang J6 papers · 2026
The First Affiliated Hospital of Xi'an Jiao Tong University, Xi'an, 710061, China. zhangjiaxjtu@xjtu.edu.cn.
Papers in Europe PMC - 04Zhang L6 papers · 2026
Institute of Cancer Research, Xinqiao Hospital, ARMY Medical University, Chongqing, China.
Papers in Europe PMC - 05Zhang Y6 papers · 2025
Department of Medical Oncology, Bone and Soft Tissue Tumours Research Centre of Yunnan Province, Third Affiliated Hospital of Kunming Medical University, Tumour Hospital of Yunnan Province, Kunming, Yunnan, 650118, PR China. yangyaihao@126.com.
Papers in Europe PMC - 06Jiang Y5 papers · 2023
Department of Radiation Oncology, Peking University Third Hospital, 49 Huayuan North Road, Beijing, 100191, People's Republic of China.
Papers in Europe PMC - 07Li Y5 papers · 2023
Department of Interventional Medicine, The Second Hospital of Shandong University, Jinan, China. lyl.pro@sdu.edu.cn.
Papers in Europe PMC - 08Chen X4 papers · 2026
Department of Oncology, Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital, Nanjing, People's Republic of China.
Papers in Europe PMC - 09Li X4 papers · 2025
Department of Ultrasound, Chinese General Hospital of Armed Police Forces No. 69 Yongding Road, Beijing 100039, China ; Department of Interventional Ultrasound, Chinese PLA General Hospital No. 28 Fuxing Road, Beijing 100853, China.
Papers in Europe PMC - 10Li Z4 papers · 2025
Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Pathology, Peking University Cancer Hospital & Institute, Beijing, People's Republic of China.
Papers in Europe PMC
Clinical research
Is a treatment being tested?
0
interventional trials for this specific condition
No interventional trial testing a treatment matched this specific condition name on ClinicalTrials.gov (observational studies and pan-disease registries are listed separately when present).
Data as of 27 July 2026
No matched interventional trials. This is true for 73% of diseases in the trials denominator (5114 of 7003). Here are the researchers publishing on it.
high confidence · 36.5th percentile (trials denominator)
Recruiting interventional trials
From the matched ClinicalTrials.gov set
No interventional trial testing a treatment was found for this specific condition name on ClinicalTrials.gov.
See who's working on it — people publishing on this disease are often the practical next contact when no trial is listed.
Where to find support
We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:
India — NPRD
Last verified 2026-07-26This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.
Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.
How we counted this
Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored on the overview but are not added to the query string.
"Radiation myelitis"
ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):
"Radiation myelitis"
Study-type breakdown: 0 interventional · 0 observational · 0 expanded access. Only interventional studies enter the trial headline.
Query health: ok — strategies attempted: phrase; with hits: phrase
Run this search on ClinicalTrials.gov
Confidence reasoning
- Preferred label is multi-word and distinctive
- No synonyms dropped by stoplist
- No label/synonym collisions with other diseases in this corpus
Ingested 2026-07-27T03:29:30.460Z