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ORPHA:85410

Oligoarticular juvenile idiopathic arthritis

high confidenceDisorder

Also known as: Oligoarticular JIA · Pauciarticular chronic arthritis

Query health: suspect — Only one of 2 strategies returned hits (phrase).

Publications

3,392

95.6th percentile

Trials

1

Interventional, condition-specific

Researchers

1,284

Distinct authors in sample

Gene link

—

Readiness

2/6

Stages with a signal

Clinical definition (Orphanet)

A rare inflammatory rheumatic disease characterized by juvenile onset arthritis that affects fewer than 5 joints during the first 6 months after disease onset.

How rare: 1-5 / 10 000 — about one to five people per ten thousand (still uncommon, but less ultra-rare).

Orphanet entry

Cross-references

Joined from Mondo / Orphanet. MeSH labels may enter searches; UMLS / OMIM / NCIT are stored for reference.

Additional Mondo synonyms (2)

Pauciarticular JIA · Pauciarticular juvenile idiopathic arthritis

Research stages

Trial readiness signals

Where this condition sits on an open-data research pipeline — not how close a treatment is, and not medical advice. Empty stages often mean “not in these databases under this Mondo ID,” not “impossible.”

2/6 stages with a signal

An interventional trial matched this condition name on ClinicalTrials.gov — see trials below.

  1. Gene identifiedNot found

    No GenCC disease–gene assertion in this build

  2. LiteraturePresent

    3,392 matched papers (2,160 in last 10 years) Source

  3. Phenotype characterisedNot checked

    Not yet enriched from Monarch / HPO

  4. Animal modelNot checked

    Not yet enriched from Monarch / Alliance

  5. Orphan designationNot checked

    FDA/EMA orphan-drug designation not enriched yet

  6. Interventional trialPresent

    1 matched on ClinicalTrials.gov

Biology

Genes and phenotypes

Gene–disease validity from GenCC, plus phenotypes and animal models joined from Monarch Initiative via Mondo ID — not a clinical diagnosis aid.

Do we know what causes it?

Not yet — the cause hasn't been pinned down in GenCC.

No strong gene–disease assertion joined for this Orphanet entity.

Phenotypes (Monarch / HPO)

Not enriched in this build — Monarch phenotype joins were not run for this record.

Animal models (Monarch / Alliance)

Not enriched in this build.

Literature

Is anyone studying this?

3,392

3,392 papers have been published on this condition. That is a real research literature — still far smaller than common diseases (breast cancer: over 700,000 papers). Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=5449) is 41.

3,392 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 41 (publications denominator n=5449).

2,160 in the last 10 years · high confidence · 95.6th percentile (publications denominator)

Phrase hits: 3,392 · MeSH hits: 0

Open Europe PMC search

Who's working on it?

1,284

Distinct author names in 200 sampled papers — named people below.

Who's working on it?

People publishing on this condition (sampled Europe PMC records). Affiliation is the most recent found in that sample.

  1. 01
    Kahn R9 papers · 2026

    Wallenberg Center for Molecular Medicine, Lund University, Lund, Sweden.

    Papers in Europe PMC
  2. 02
    Mossberg A9 papers · 2026

    Wallenberg Center for Molecular Medicine, Lund University, Lund, Sweden.

    Papers in Europe PMC
  3. 03
    Schmidt T9 papers · 2026

    Wallenberg Center for Molecular Medicine, Lund University, Lund, Sweden.

    Papers in Europe PMC
  4. 04
    Berthold E8 papers · 2024

    Department of Rheumatology, Clinical Sciences Lund, Lund University, Lund, Sweden.

    Papers in Europe PMC
  5. 05
    Bilginer Y8 papers · 2025

    Division of Pediatric Rheumatology, Department of Pediatrics, Hacettepe University, Ankara, Türkiye.

    Papers in Europe PMC
  6. 06
    Kahn F8 papers · 2026

    Department of Infection Medicine, Clinical Sciences Lund, Lund University, Lund, Sweden.

    Papers in Europe PMC
  7. 07
    Arve-Butler S7 papers · 2023

    Department of Rheumatology, Clinical Sciences Lund, Lund University, Lund, Sweden.

    Papers in Europe PMC
  8. 08
    Bengtsson AA7 papers · 2026

    Department of Rheumatology, Clinical Sciences Lund, Lund University, Lund, Sweden.

    Papers in Europe PMC
  9. 09
    Karagöl C7 papers · 2025

    Division of Pediatric Rheumatology, Department of Pediatrics, University of Health Sciences, Ankara Bilkent City Hospital, Bilkent, 06800, Ankara, Turkey.

    Papers in Europe PMC
  10. 10
    Batu ED6 papers · 2025

    Division of Pediatric Rheumatology, Department of Pediatrics, Hacettepe University, Ankara, Türkiye.

    Papers in Europe PMC

Clinical research

Is a treatment being tested?

1

interventional trials for this specific condition

1 interventional trial matched this specific condition name; none in our sample are currently recruiting. 175 trials are registered for juvenile idiopathic arthritis, the broader category — shown separately because they may or may not enrol this specific subtype.

Data as of 27 July 2026

1 interventional trial — more than 73% of diseases in the trials denominator have none at all (5114 of 7003; this disease is at the 76.8th percentile).

high confidence · 76.8th percentile (trials denominator)

Recruiting interventional trials

From the matched ClinicalTrials.gov set

1 interventional trials matched after quoted-phrase search and title/condition post-filter.

No currently recruiting studies in the matched set. Open the same search on ClinicalTrials.gov.

Broader category: juvenile idiopathic arthritis

175

Interventional trials for the parent category, exclusive of NCT IDs already counted above. Eligibility for this subtype is not guaranteed.

Worth raising with a clinician. How we count trials.

Recruiting under the broader category

Observational and natural-history studies

1 observational study matches this condition. These do not test a treatment and are not counted in the interventional-trial headline, but they are genuine research: natural-history work often defines the endpoints needed for a future rare-disease trial, and families may be able to enroll.

Recruiting or not-yet-recruiting

Open the complete matched search on ClinicalTrials.gov

Where to find support

We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:

India — NPRD

Last verified 2026-07-26

This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.

Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.

How we counted this

Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored on the overview but are not added to the query string.

"Oligoarticular juvenile idiopathic arthritis" OR "Oligoarticular JIA" OR "Pauciarticular chronic arthritis" OR "Pauciarticular JIA" OR "Pauciarticular juvenile idiopathic arthritis"

Run this search on Europe PMC

MeSH descriptor terms unioned into the query: Juvenile pauciarticular chronic arthritis

ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):

"Oligoarticular juvenile idiopathic arthritis" OR "Oligoarticular JIA" OR "Pauciarticular chronic arthritis" OR "Pauciarticular JIA" OR "Pauciarticular juvenile idiopathic arthritis" OR "Juvenile pauciarticular chronic arthritis"

Interventional trials matched via: phrase (mesh = registered under a MeSH descriptor no name phrase would catch; recall-expansion = gene / selected parent terms used only for trials).

Study-type breakdown: 1 interventional · 1 observational · 0 expanded access. Only interventional studies enter the trial headline.

Parent-category trials query:

"juvenile idiopathic arthritis"

Query health: suspect — strategies attempted: phrase, mesh; with hits: phrase

Run this search on ClinicalTrials.gov

Confidence reasoning

  • Preferred label is multi-word and distinctive
  • No synonyms dropped by stoplist
  • No label/synonym collisions with other diseases in this corpus

Ingested 2026-07-27T02:59:54.189Z