ORPHA:764
Pyomyositis
Also known as: Myositis purulenta tropica · Myositis tropicans · PM · Suppurative myositis · Tropical pyomyositis
Publications
2,754
Trials
2
Interventional, condition-specific
Researchers
997
Distinct authors in sample
Gene link
—
Readiness
2/6
Stages with a signal
Clinical definition (Orphanet)
Pyomyositis (PM) is a rare primary bacterial infection of the skeletal muscle, usually resulting from hematogenous spread or due to muscle injury, and characterized by pain and tenderness in the affected muscle, fever and abscess formation.
How rare: How common this is has not been clearly measured.
Cross-references
Joined from Mondo / Orphanet. MeSH labels may enter searches; UMLS / OMIM / NCIT are stored for reference.
- MONDO:0019168
- MeSH:D052880
- UMLS:C0041188
- NCIT:C128382
Additional Mondo synonyms (4)
myositis purulenta tropica · myositis tropicans · suppurative myositis · tropical pyomyositis
Research stages
Trial readiness signals
Where this condition sits on an open-data research pipeline — not how close a treatment is, and not medical advice. Empty stages often mean “not in these databases under this Mondo ID,” not “impossible.”
2/6 stages with a signal
An interventional trial matched this condition name on ClinicalTrials.gov — see trials below.
- Gene identifiedNot found
No GenCC disease–gene assertion in this build
- LiteraturePresent
2,754 matched papers (1,157 in last 10 years) Source
- Phenotype characterisedNot checked
Not yet enriched from Monarch / HPO
- Animal modelNot checked
Not yet enriched from Monarch / Alliance
- Orphan designationNot checked
FDA/EMA orphan-drug designation not enriched yet
- Interventional trialPresent
2 matched on ClinicalTrials.gov
Biology
Genes and phenotypes
Gene–disease validity from GenCC, plus phenotypes and animal models joined from Monarch Initiative via Mondo ID — not a clinical diagnosis aid.
Do we know what causes it?
Not yet — the cause hasn't been pinned down in GenCC.
No strong gene–disease assertion joined for this Orphanet entity.
Phenotypes (Monarch / HPO)
Not enriched in this build — Monarch phenotype joins were not run for this record.
Animal models (Monarch / Alliance)
Not enriched in this build.
Literature
Is anyone studying this?
2,754
2,754 papers have been published on this condition. That is a real research literature — still far smaller than common diseases (breast cancer: over 700,000 papers). Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=5449) is 41.
2,754 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 41 (publications denominator n=5449).
1,157 in the last 10 years · low confidence
Phrase hits: 2,754 · MeSH hits: 0
Who's working on it?
997
Distinct author names in 200 sampled papers — named people below.
Who's working on it?
People publishing on this condition (sampled Europe PMC records). Affiliation is the most recent found in that sample.
- 01Khan A3 papers · 2026
Orthopaedics and Traumatology Unit, Surgery Department, Geneva University Hospitals, CH-1205 Geneva, Switzerland.
Papers in Europe PMC - 02Crawford H2 papers · 2026
University of Auckland Faculty of Medical and Health Sciences, New Zealand.
Papers in Europe PMC - 03Derbel H2 papers · 2024
Radiology Department, AP-HP (Assistance Publique-Hôpitaux de Paris), Henri Mondor Universitary Hospital, Créteil, F-94010, France.
Papers in Europe PMC - 04Gouveia C2 papers · 2026
Pediatric Infectious Diseases, Unidade Local de Saúde São José - Hospital Dona Estefânia, Lisbon, PRT.
Papers in Europe PMC - 05Hamine S2 papers · 2024
Nephrology and Renal Transplantation Department, AP-HP (Assistance Publique-Hôpitaux de Paris), Henri Mondor Universitary Hospital, Créteil, F-94010, France.
Papers in Europe PMC - 06Hunter S2 papers · 2026
University of Auckland Faculty of Medical and Health Sciences, New Zealand.
Papers in Europe PMC - 07Kiratli K2 papers · 2026
Department of Infectious Diseases and Clinical Microbiology, Ataturk Training and Research Hospital, İzmir Katip Celebi University, İzmir, Türkiye.
Papers in Europe PMC - 08Kumar A2 papers · 2026
Department of Clinical Immunology and Rheumatology, Army Hospital Research and Referral, New Delhi, India.
Papers in Europe PMC - 09Kumar D2 papers · 2025
Department of Internal Medicine, All India Institute of Medical Sciences, Jodhpur, India.
Papers in Europe PMC - 10Kumar R2 papers · 2025
Department of Internal Medicine, Sir Ganga Ram Hospital, New Delhi, India. Electronic address: rahullakraj@gmail.com.
Papers in Europe PMC
Clinical research
Is a treatment being tested?
2
interventional trials for this specific condition
2 interventional trials matched this specific condition name; none in our sample are currently recruiting.
Data as of 27 July 2026
2 interventional trials — more than 73% of diseases in the trials denominator have none at all (5114 of 7003; this disease is at the 82.4th percentile).
low confidence · 82.4th percentile (trials denominator)
Recruiting interventional trials
From the matched ClinicalTrials.gov set
2 interventional trials matched after quoted-phrase search and title/condition post-filter.
No currently recruiting studies in the matched set. Open the same search on ClinicalTrials.gov.
Where to find support
We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:
India — NPRD
Last verified 2026-07-26This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.
Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.
How we counted this
Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored on the overview but are not added to the query string.
"Pyomyositis" OR "Myositis purulenta tropica" OR "Myositis tropicans" OR "Suppurative myositis" OR "Tropical pyomyositis"
ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):
"Pyomyositis" OR "Myositis purulenta tropica" OR "Myositis tropicans" OR "Suppurative myositis" OR "Tropical pyomyositis"
Interventional trials matched via: phrase (mesh = registered under a MeSH descriptor no name phrase would catch; recall-expansion = gene / selected parent terms used only for trials).
Study-type breakdown: 2 interventional · 0 observational · 0 expanded access. Only interventional studies enter the trial headline.
Query health: ok — strategies attempted: phrase; with hits: phrase
Run this search on ClinicalTrials.gov
Synonyms dropped by stoplist: PM
Confidence reasoning
- Preferred label is short or not clearly distinctive
- 1 synonym(s) dropped by stoplist (may under-count)
- No label/synonym collisions with other diseases in this corpus
Ingested 2026-07-26T15:16:11.589Z