ORPHA:723290
Pregnancy-associated spontaneous coronary artery dissection
Also known as: P-SCAD · PASCAD
Publications
150
Trials
0
Interventional, condition-specific
Researchers
901
Distinct authors in sample
Gene link
—
Readiness
1/6
Stages with a signal
How rare: How common this is has not been clearly measured.
Research stages
Trial readiness signals
Where this condition sits on an open-data research pipeline — not how close a treatment is, and not medical advice. Empty stages often mean “not in these databases under this Mondo ID,” not “impossible.”
1/6 stages with a signal
Research-stage checklist from open sources (GenCC, literature, Monarch when enriched, ClinicalTrials.gov). Not a prognosis or care recommendation.
- Gene identifiedNot found
No GenCC disease–gene assertion in this build
- LiteraturePresent
150 matched papers (140 in last 10 years) Source
- Phenotype characterisedNot checked
Not yet enriched from Monarch / HPO
- Animal modelNot checked
Not yet enriched from Monarch / Alliance
- Orphan designationNot checked
FDA/EMA orphan-drug designation not enriched yet
- Interventional trialNot found
No matched interventional trial under our ClinicalTrials.gov rules
Biology
Genes and phenotypes
Gene–disease validity from GenCC, plus phenotypes and animal models joined from Monarch Initiative via Mondo ID — not a clinical diagnosis aid.
Do we know what causes it?
Not yet — the cause hasn't been pinned down in GenCC.
No strong gene–disease assertion joined for this Orphanet entity.
Phenotypes (Monarch / HPO)
Not enriched in this build — Monarch phenotype joins were not run for this record.
Animal models (Monarch / Alliance)
Not enriched in this build.
Literature
Is anyone studying this?
150
150 papers have ever been published on this condition (under this name). For scale, breast cancer has over 700,000. Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=5449) is 41.
150 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 41 (publications denominator n=5449).
140 in the last 10 years · low confidence
Phrase hits: 150 · MeSH hits: 0
Who's working on it?
901
Distinct author names in 150 sampled papers — named people below.
Who's working on it?
No interventional trial matched this name; these authors publish on it in the sampled literature — a practical starting point for contact.
- 01Tweet MS11 papers · 2026
Department of Cardiovascular Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota.
Papers in Europe PMC - 02Adlam D10 papers · 2026
Department of Cardiovascular Sciences, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester LE5 4PW, UK.
Papers in Europe PMC - 03Hayes SN10 papers · 2026
Department of Cardiovascular Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota.
Papers in Europe PMC - 04Samani NJ7 papers · 2026
Department of Cardiovascular Sciences, NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester LE5 4PW, UK.
Papers in Europe PMC - 05Saw J6 papers · 2025
Vancouver General Hospital, Vancouver, British Columbia, Canada.
Papers in Europe PMC - 06Alfonso F5 papers · 2025
Department of Cardiology, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IIS-IP), Universidad Autónoma de Madrid, CIBER-CV, Madrid, Spain.
Papers in Europe PMC - 07Gulati R5 papers · 2021
Department of Cardiovascular Medicine Mayo Clinic Rochester MN.
Papers in Europe PMC - 08Kądziela J5 papers · 2026
Department of Invasive Cardiology and Angiology, National Institute of Cardiology, Warsaw, Poland (J.K.).
Papers in Europe PMC - 09Frawley J4 papers · 2023
School of Public Health, Faculty of Health, University of Technology Sydney, Ultimo, NSW, Australia.
Papers in Europe PMC - 10Hutchens J4 papers · 2023
School of Public Health, Faculty of Health, University of Technology Sydney, Ultimo, NSW, Australia. jane.hutchens@student.uts.edu.au.
Papers in Europe PMC
Clinical research
Is a treatment being tested?
0
interventional trials for this specific condition
No interventional trial testing a treatment matched this specific condition name on ClinicalTrials.gov (observational studies and pan-disease registries are listed separately when present).
Data as of 27 July 2026
No matched interventional trials. This is true for 73% of diseases in the trials denominator (5114 of 7003). Here are the researchers publishing on it.
low confidence · 36.5th percentile (trials denominator)
Recruiting interventional trials
From the matched ClinicalTrials.gov set
No interventional trial testing a treatment was found for this specific condition name on ClinicalTrials.gov.
See who's working on it — people publishing on this disease are often the practical next contact when no trial is listed.
Where to find support
We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:
India — NPRD
Last verified 2026-07-26This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.
Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.
How we counted this
Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored on the overview but are not added to the query string.
"Pregnancy-associated spontaneous coronary artery dissection" OR "P-SCAD" OR "PASCAD"
ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):
"Pregnancy-associated spontaneous coronary artery dissection" OR "P-SCAD" OR "PASCAD"
Study-type breakdown: 0 interventional · 0 observational · 0 expanded access. Only interventional studies enter the trial headline.
Query health: ok — strategies attempted: phrase; with hits: phrase
Run this search on ClinicalTrials.gov
Confidence reasoning
- Preferred label is multi-word and distinctive
- No synonyms dropped by stoplist
- No label/synonym collisions with other diseases in this corpus
- No Orphanet definition and no Mondo IDs — likely taxonomy scaffolding; confidence capped at low
Ingested 2026-07-27T21:21:40.321Z