ORPHA:697096
Cryptosporidiosis
Also known as: Cryptosporidium infection
Publications
20,179
Trials
23
Interventional, condition-specific
Researchers
1,262
Distinct authors in sample
Gene link
—
Readiness
2/6
Stages with a signal
How rare: 1-9 / 100 000 — about one to nine people per hundred thousand.
Research stages
Trial readiness signals
Where this condition sits on an open-data research pipeline — not how close a treatment is, and not medical advice. Empty stages often mean “not in these databases under this Mondo ID,” not “impossible.”
2/6 stages with a signal
An interventional trial matched this condition name on ClinicalTrials.gov — see trials below.
- Gene identifiedNot found
No GenCC disease–gene assertion in this build
- LiteraturePresent
20,179 matched papers (9,363 in last 10 years) Source
- Phenotype characterisedNot checked
Not yet enriched from Monarch / HPO
- Animal modelNot checked
Not yet enriched from Monarch / Alliance
- Orphan designationNot checked
FDA/EMA orphan-drug designation not enriched yet
- Interventional trialPresent
23 matched on ClinicalTrials.gov (3 recruiting in sample)
Biology
Genes and phenotypes
Gene–disease validity from GenCC, plus phenotypes and animal models joined from Monarch Initiative via Mondo ID — not a clinical diagnosis aid.
Do we know what causes it?
Not yet — the cause hasn't been pinned down in GenCC.
No strong gene–disease assertion joined for this Orphanet entity.
Phenotypes (Monarch / HPO)
Not enriched in this build — Monarch phenotype joins were not run for this record.
Animal models (Monarch / Alliance)
Not enriched in this build.
Literature
Is anyone studying this?
20,179
20,179 papers — among the better-studied rare conditions, though still a fraction of common-disease literature (breast cancer: over 700,000). Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=5449) is 41.
20,179 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 41 (publications denominator n=5449).
9,363 in the last 10 years · low confidence
Phrase hits: 20,179 · MeSH hits: 0
Who's working on it?
1,262
Distinct author names in 200 sampled papers — named people below.
Who's working on it?
People publishing on this condition (sampled Europe PMC records). Affiliation is the most recent found in that sample.
- 01Li J7 papers · 2026
College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China; Key Laboratory of Quality and Safety Control of Poultry Products, Ministry of Agriculture and Rural Affairs, Zhengzhou 450046, China; International Joint Research Laboratory for Zoonotic Diseases of Henan, Zhengzhou 450046, China.
Papers in Europe PMC - 02Robertson LJ6 papers · 2026
Parasitology, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Ås, 1433, Norway.
Papers in Europe PMC - 03Hanevik K5 papers · 2026
Department of Clinical Science, Faculty of Medicine, University of Bergen, Bergen, Norway.
Papers in Europe PMC - 04Katzer F5 papers · 2025
Moredun Research Institute, Pentlands Science Park, Penicuik, EH26 0PZ, Scotland, UK.
Papers in Europe PMC - 05Wang Y5 papers · 2026
College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot, China.
Papers in Europe PMC - 06Zhang L5 papers · 2026
College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China; Key Laboratory of Quality and Safety Control of Poultry Products, Ministry of Agriculture and Rural Affairs, Zhengzhou 450046, China; International Joint Research Laboratory for Zoonotic Diseases of Henan, Zhengzhou 450046, China.
Papers in Europe PMC - 07
- 08Ahmed SAA4 papers · 2026
Department of Medical Parasitology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
Papers in Europe PMC - 09Johansen ØH4 papers · 2026
Microbiology Laboratory, Southern Health and Social Care Trust, Portadown, BT63 5QQ, Northern Ireland, UK.
Papers in Europe PMC - 10Karanis P4 papers · 2026
Department of Basic and Clinical Sciences, University of Nicosia Medical School, Nicosia, Cyprus.
Papers in Europe PMC
Clinical research
Is a treatment being tested?
23
interventional trials for this specific condition
23 interventional trials matched this specific condition name; 3 currently recruiting in our sample.
Data as of 27 July 2026
23 interventional trials — more than 73% of diseases in the trials denominator have none at all (5114 of 7003; this disease is at the 94.9th percentile).
low confidence · 94.9th percentile (trials denominator)
Recruiting interventional trials
From the matched ClinicalTrials.gov set
23 interventional trials matched after quoted-phrase search and title/condition post-filter.
- NCT07388615·RECRUITING·The Effect of Echinacea (Immulant ®) in the Treatment of CRYPTOSPORIDIOSIS in Immunocompromised Children
Conditions: Cryptosporidium Infection·Matched via name phrase
- NCT07249463·RECRUITING·Study Testing the Efficacy, Safety, and Tolerability of EDI048 in Cryptosporidium Infection Model in Healthy Adults
Conditions: Cryptosporidiosis·Matched via name phrase
- NCT06600711·NOT YET RECRUITING·Nitazoxanide for Treatment of Cryptosporidium in Children
Conditions: Cryptosporidiosis·Matched via name phrase
Observational and natural-history studies
8 observational studies match this condition. These do not test a treatment and are not counted in the interventional-trial headline, but they are genuine research: natural-history work often defines the endpoints needed for a future rare-disease trial, and families may be able to enroll.
Recruiting or not-yet-recruiting
- NCT07716410·RECRUITING·A Study to Characterize the Clinical Presentation and Course of Cryptosporidium in Pediatric Participants
Conditions: Cryptosporidiosis·Matched via name phrase
Where to find support
We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:
India — NPRD
Last verified 2026-07-26This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.
Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.
How we counted this
Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored on the overview but are not added to the query string.
"Cryptosporidiosis" OR "Cryptosporidium infection"
ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):
"Cryptosporidiosis" OR "Cryptosporidium infection"
Interventional trials matched via: phrase (mesh = registered under a MeSH descriptor no name phrase would catch; recall-expansion = gene / selected parent terms used only for trials).
Study-type breakdown: 23 interventional · 8 observational · 0 expanded access. Only interventional studies enter the trial headline.
Query health: ok — strategies attempted: phrase; with hits: phrase
Run this search on ClinicalTrials.gov
Confidence reasoning
- Preferred label is short or not clearly distinctive
- No synonyms dropped by stoplist
- No label/synonym collisions with other diseases in this corpus
- No Orphanet definition and no Mondo IDs — likely taxonomy scaffolding; confidence capped at low
Ingested 2026-07-27T20:46:59.220Z