ORPHA:675380
Isolated segmental infantile hemangioma
Also known as: Isolated segmental infantile haemangioma · Large segmental haemangioma · Large segmental hemangioma · Segmental haemangioma of infancy · Segmental hemangioma of infancy
Query health: suspect — Only one of 2 strategies returned hits (phrase).
Is anyone studying this?
25
25 papers have ever been published on this condition (under this name). For scale, breast cancer has over 700,000. Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=183) is 38.
25 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 38 (publications denominator n=183).
11 in the last 10 years · high confidence · 32th percentile (publications denominator)
Is a treatment being tested?
0
trials for this specific condition
No interventional trial testing a treatment matched this specific condition name on ClinicalTrials.gov (observational studies and pan-disease registries are listed separately when present). 54 trials are registered for hemangioma, the broader category — shown separately because they may or may not enrol this specific subtype.
Data as of 26 July 2026
54
trials for hemangioma, the broader category this belongs to
Trials registered for a broader category may or may not enrol people with this specific subtype — eligibility criteria vary, and the trial record often doesn't say. Worth raising with a clinician. How we count trials.
No matched interventional trials. This is true for 59.2% of diseases in the trials denominator (151 of 255). Here are the researchers publishing on it.
high confidence · 29.6th percentile (trials denominator)
Do we know what causes it?
Not yet — the cause hasn't been pinned down in GenCC.
No strong gene–disease assertion joined for this Orphanet entity.
Who's working on it?
128
Distinct author names in 25 sampled papers — named people below.
Who's working on it?
No interventional trial matched this name; these authors publish on it in the sampled literature — a practical starting point for contact.
- 01Siegel DH4 papers · 2021
Department of Dermatology, Medical College of Wisconsin, Milwaukee, WI.
Papers in Europe PMC - 02Chamlin SL3 papers · 2021
Division of Pediatric Dermatology, The Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL.
Papers in Europe PMC - 03Drolet BA3 papers · 2021
Departments of Dermatology and Pediatrics, Medical College of Wisconsin, Milwaukee, WI. Electronic address: bdrolet@mcw.edu.
Papers in Europe PMC - 04Frieden IJ3 papers · 2021
Department of Dermatology, University of California, San Francisco, San Francisco, CA.
Papers in Europe PMC - 05Garzon MC2 papers · 2021
Departments of Dermatology and Pediatrics, Columbia University, New York, NY.
Papers in Europe PMC - 06Haggstrom AN2 papers · 2021
Departments of Dermatology and Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana.
Papers in Europe PMC - 07Liang MG2 papers · 2021
Department of Dermatology, Harvard Medical School, Boston, MA.
Papers in Europe PMC - 08Mancini AJ2 papers · 2021
Departments of Pediatrics and Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Papers in Europe PMC - 09Pope E2 papers · 2021
Section of Pediatric Dermatology, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Papers in Europe PMC - 10Tollefson MM2 papers · 2021
Department of Dermatology and Pediatrics, Mayo Clinic, Rochester, MN.
Papers in Europe PMC
Recruiting interventional trials
Trials testing a treatment from the matched ClinicalTrials.gov set
No interventional trial testing a treatment was found for this specific condition name on ClinicalTrials.gov.
54 interventional trials matched hemangioma, the broader category — see the summary above. Those studies are not counted in the condition-specific total.
Where to find support
We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:
India — NPRD
Last verified 2026-07-26This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.
Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.
How we counted this
Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored below but are not added to the query string.
"Isolated segmental infantile hemangioma" OR "Isolated segmental infantile haemangioma" OR "Large segmental haemangioma" OR "Large segmental hemangioma" OR "Segmental haemangioma of infancy" OR "Segmental hemangioma of infancy"
ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):
"Isolated segmental infantile hemangioma" OR "Isolated segmental infantile haemangioma" OR "Large segmental haemangioma" OR "Large segmental hemangioma" OR "Segmental haemangioma of infancy" OR "Segmental haemangioma of the infancy" OR "Segmental hemangioma of infancy" OR "Segmental hemangioma of the infancy" OR "infantile hemangioma of rare localization"
Study-type breakdown: 0 interventional · 0 observational · 0 expanded access. Only interventional studies enter the trial headline.
Cross-references (from Mondo): UMLS:C5925079
Query health: suspect — strategies attempted: phrase, recall-expansion; with hits: phrase
Run this search on ClinicalTrials.gov
Confidence reasoning
- Preferred label is multi-word and distinctive
- No synonyms dropped by stoplist
- No label/synonym collisions with other diseases in this corpus