ORPHA:664912
Neonatal renal venous thrombosis
Also known as: NRVT · Neonatal RVT
Clinical definition (Orphanet)
A rare vascular condition characterized by the formation of a thrombus (blood clot) in the renal vein of a newborn infant, typically within the first 28 days of life. This condition can cause renal (kidney) ischemia, and may lead to kidney damage, swelling, and potential loss of kidney function. renal vein thrombosis (NRVT) can affect one kidney (unilateral) or both kidneys (bilateral), with the severity of symptoms often depending on the extent of the clot and the number of affected kidneys.
How rare: How common this is has not been clearly measured.
Is anyone studying this?
50
50 papers have ever been published on this condition (under this name). For scale, breast cancer has over 700,000. Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=183) is 38.
50 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 38 (publications denominator n=183).
10 in the last 10 years · medium confidence · 30.3th percentile (publications denominator)
Is a treatment being tested?
0
trials for this specific condition
No interventional trial testing a treatment matched this specific condition name on ClinicalTrials.gov (observational studies and pan-disease registries are listed separately when present).
Data as of 26 July 2026
No matched interventional trials. This is true for 59.2% of diseases in the trials denominator (151 of 255). Here are the researchers publishing on it.
medium confidence · 29.6th percentile (trials denominator)
Do we know what causes it?
Not yet — the cause hasn't been pinned down in GenCC.
No strong gene–disease assertion joined for this Orphanet entity.
Who's working on it?
173
Distinct author names in 50 sampled papers — named people below.
Who's working on it?
No interventional trial matched this name; these authors publish on it in the sampled literature — a practical starting point for contact.
- 01Nowak-Göttl U3 papers · 2012
Thrombosis and Hemostasis Unit, Institute of Clinical Chemistry, University Hospital Kiel, Kiel, Germany.
Papers in Europe PMC - 02Chan AK2 papers · 2021
Division of Pediatric Hematology/Oncology, Department of Pediatrics, McMaster Children's Hospital, McMaster University, Hamilton, ON, Canada.
Papers in Europe PMC - 03Dauger S2 papers · 2011
Service de réanimation et surveillance continue pédiatriques, pôle de pédiatrie aiguë et médecine interne, hôpital Robert-Debré, AP-HP, université Paris Diderot-Paris 7, 48, boulevard Serurier, 75019 Paris, France. stephane.dauger@rdb.aphp.fr
Papers in Europe PMC - 04Garnier A2 papers · 2011Papers in Europe PMC
- 05Massicotte P2 papers · 2021
Department of Pediatrics, University of Alberta, Edmonton, Alberta.
Papers in Europe PMC - 06Michot C2 papers · 2011
Service de réanimation et surveillance continue pédiatriques, pôle de pédiatrie aiguë et médecine interne, hôpital Robert-Debré, AP-HP, université Paris-Diderot, Paris-VII, 48, boulevard Sérurier, 75019 Paris, France.
Papers in Europe PMC - 07Yang PH2 papers · 2014
Division of Neonatology, Chang Gung Children's Hospital and Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Papers in Europe PMC - 08Zhang L2 papers · 2023
Department of Endovascular Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Papers in Europe PMC - 09Abboud MR1 paper · 2009Papers in Europe PMC
- 10Aigbe MO1 paper · 2006Papers in Europe PMC
Recruiting interventional trials
Trials testing a treatment from the matched ClinicalTrials.gov set
No interventional trial testing a treatment was found for this specific condition name on ClinicalTrials.gov.
See who's working on it above — people publishing on this disease are often the practical next contact when no trial is listed.
Where to find support
We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:
India — NPRD
Last verified 2026-07-26This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.
Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.
How we counted this
Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored below but are not added to the query string.
"Neonatal renal venous thrombosis" OR "Neonatal RVT"
ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):
"Neonatal renal venous thrombosis" OR "Neonatal RVT"
Study-type breakdown: 0 interventional · 0 observational · 0 expanded access. Only interventional studies enter the trial headline.
Cross-references (from Mondo): UMLS:C5925061
Query health: ok — strategies attempted: phrase; with hits: phrase
Run this search on ClinicalTrials.gov
Synonyms dropped by stoplist: NRVT
Confidence reasoning
- Preferred label is multi-word and distinctive
- 1 synonym(s) dropped by stoplist (may under-count)
- No label/synonym collisions with other diseases in this corpus