RARE DISEASERESEARCH ATLAS

ORPHA:645814

Primary pulmonary tuberculosis

high confidence

Also known as: Tuberculosis of respiratory system

Orphanet entry

Is anyone studying this?

707

707 papers have been published on this condition. That is a real research literature — still far smaller than common diseases (breast cancer: over 700,000 papers). Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=183) is 38.

707 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 38 (publications denominator n=183).

143 in the last 10 years · high confidence · 75.1th percentile (publications denominator)

Is a treatment being tested?

0

trials for this specific condition

No interventional trial testing a treatment matched this specific condition name on ClinicalTrials.gov (observational studies and pan-disease registries are listed separately when present). 157 trials are registered for pulmonary tuberculosis, the broader category — shown separately because they may or may not enrol this specific subtype.

Data as of 26 July 2026

157

trials for pulmonary tuberculosis, the broader category this belongs to

Trials registered for a broader category may or may not enrol people with this specific subtype — eligibility criteria vary, and the trial record often doesn't say. Worth raising with a clinician. How we count trials.

No matched interventional trials. This is true for 59.2% of diseases in the trials denominator (151 of 255). Here are the researchers publishing on it.

high confidence · 29.6th percentile (trials denominator)

Do we know what causes it?

Not yet — the cause hasn't been pinned down in GenCC.

No strong gene–disease assertion joined for this Orphanet entity.

Who's working on it?

1,001

Distinct author names in 200 sampled papers — named people below.

Who's working on it?

No interventional trial matched this name; these authors publish on it in the sampled literature — a practical starting point for contact.

  1. 01
    Andronikou S8 papers · 2025

    Department of Paediatric Radiology, Red Cross Children's Hospital, Klipfontein Road, Rondebosch, Cape Town, South Africa. docsav@mweb.co.za

    Papers in Europe PMC
  2. 02
    Zhang X8 papers · 2024

    1 Nanjing Chest Hospital, Nanjing 210029, China ; 2 The Fifth People's Hospital of Suzhou, Suzhou 215000, China ; 3 The Third People's Hospital of Changzhou, Changzhou 213000, China ; 4 The Third People's Hospital of Zhenjiang, Zhenjiang 215005, China ; 5 The Fifth People's Hospital of Wuxi, Wuxi 214000, China ; 6 The Sixth People's Hospital of Nantong, Nantong 226011, China ; 7 The Fourth People's Hospital of Huai'an, Huai'an 223002, China ; 8 Xuzhou Infectious Disease Hospital, Xuzhou 221000, China ; 9 The Second People's Hospital of Changshu, Changshu 215500, China ; 10 The Second People's Hospital of Yancheng, Yancheng 224002, China ; 11 The Third People's Hospital of Yangzhou, Yangzhou 225000, China ; 12 Department of Epidemiology, West China School of Public Health, Sichuan University, Chengdu 610041, China.

    Papers in Europe PMC
  3. 03
    Goussard P5 papers · 2025

    Department of Paediatrics and Child Health, Tygerberg Hospital and the University of Stellenbosch, Cape Town, South Africa.

    Papers in Europe PMC
  4. 04
    Wang Y5 papers · 2024

    Shanghai Jiao Tong University, Shanghai, China. wangyanfeng622@sjtu.edu.cn.

    Papers in Europe PMC
  5. 05
    Liu Z4 papers · 2025

    Department of Tuberculosis, Jiangxi Chest Hospital, Nanchang 330006, Jiangxi, China

    Papers in Europe PMC
  6. 06
    He Y3 papers · 2025

    Department of Tuberculosis, The Fourth People's Hospital of Nanning City, Nanning, People's Republic of China.

    Papers in Europe PMC
  7. 07
    Li L3 papers · 2023

    Cadre Ward 2, Bethune International Peace Hospital, Shijiazhuang, Hebei, P.R. China.

    Papers in Europe PMC
  8. 08
    Liu J3 papers · 2023

    Department of Respiratory Medicine, Hebei Chest Hospital, Shijiazhuang, Hebei, P.R. China.

    Papers in Europe PMC
  9. 09
    Madhi SA3 papers · 2023

    South African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, University of the Witwatersrand, Johannesburg, South Africa; Infectious Diseases and Oncology Research Institute, University of the Witwatersrand, Johannesburg, South Africa; Faculty of Health Science, National Research Foundation: Vaccine Preventable Diseases, Department of Science, University of the Witwatersrand, Johannesburg, South Africa. Electronic address: shabir.madhi@wits.ac.za.

    Papers in Europe PMC
  10. 10
    Moore DP3 papers · 2023

    South African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, University of the Witwatersrand, Johannesburg, South Africa; Department of Paediatrics and Child Health, Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa.

    Papers in Europe PMC

Recruiting interventional trials

Trials testing a treatment from the matched ClinicalTrials.gov set

No interventional trial testing a treatment was found for this specific condition name on ClinicalTrials.gov.

157 interventional trials matched pulmonary tuberculosis, the broader category — see the summary above. Those studies are not counted in the condition-specific total.

Where to find support

We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:

India — NPRD

Last verified 2026-07-26

This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.

Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.

How we counted this

Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored below but are not added to the query string.

"Primary pulmonary tuberculosis" OR "Tuberculosis of respiratory system"

Run this search on Europe PMC

ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):

"Primary pulmonary tuberculosis" OR "Tuberculosis of respiratory system" OR "Tuberculosis of the respiratory system"

Study-type breakdown: 0 interventional · 0 observational · 0 expanded access. Only interventional studies enter the trial headline.

0

Query health: ok — strategies attempted: phrase; with hits: phrase

Run this search on ClinicalTrials.gov

Confidence reasoning

  • Preferred label is multi-word and distinctive
  • No synonyms dropped by stoplist
  • No label/synonym collisions with other diseases in this corpus

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