ORPHA:54251
Aseptic abscess syndrome
Also known as: Aseptic abscesses syndrome · Aseptic systemic abscesses · Corticosteroid-sensitive aseptic abscess syndrome · Disseminated aseptic abscesses
Publications
75
56.2th percentile
Trials
1
Interventional, condition-specific
Researchers
468
Distinct authors in sample
Gene link
—
Readiness
2/6
Stages with a signal
Clinical definition (Orphanet)
A rare autoinflammatory disorder characterized by recurrent attacks of fever and sterile abscesses.
How rare: <1 / 1 000 000 — fewer than one in a million. In a city the size of Kolkata, that might mean on the order of fifteen people.
Cross-references
Joined from Mondo / Orphanet. MeSH labels may enter searches; UMLS / OMIM / NCIT are stored for reference.
- MONDO:0018900
- UMLS:C4303863
Additional Mondo synonyms (3)
aseptic abscesses syndrome · aseptic systemic abscesses · disseminated aseptic abscesses
Research stages
Trial readiness signals
Where this condition sits on an open-data research pipeline — not how close a treatment is, and not medical advice. Empty stages often mean “not in these databases under this Mondo ID,” not “impossible.”
2/6 stages with a signal
An interventional trial matched this condition name on ClinicalTrials.gov — see trials below.
- Gene identifiedNot found
No GenCC disease–gene assertion in this build
- LiteraturePresent
75 matched papers (58 in last 10 years) Source
- Phenotype characterisedNot checked
Not yet enriched from Monarch / HPO
- Animal modelNot checked
Not yet enriched from Monarch / Alliance
- Orphan designationNot checked
FDA/EMA orphan-drug designation not enriched yet
- Interventional trialPresent
1 matched on ClinicalTrials.gov
Biology
Genes and phenotypes
Gene–disease validity from GenCC, plus phenotypes and animal models joined from Monarch Initiative via Mondo ID — not a clinical diagnosis aid.
Do we know what causes it?
Not yet — the cause hasn't been pinned down in GenCC.
No strong gene–disease assertion joined for this Orphanet entity.
Phenotypes (Monarch / HPO)
Not enriched in this build — Monarch phenotype joins were not run for this record.
Animal models (Monarch / Alliance)
Not enriched in this build.
Literature
Is anyone studying this?
75
75 papers have ever been published on this condition (under this name). For scale, breast cancer has over 700,000. Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=5449) is 41.
75 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 41 (publications denominator n=5449).
58 in the last 10 years · high confidence · 56.2th percentile (publications denominator)
Phrase hits: 75 · MeSH hits: 0
Who's working on it?
468
Distinct author names in 75 sampled papers — named people below.
Who's working on it?
People publishing on this condition (sampled Europe PMC records). Affiliation is the most recent found in that sample.
- 01Aumaître O5 papers · 2014Papers in Europe PMC
- 02Piette JC5 papers · 2022
Service de Médecine Interne, AP-HP Groupe Hospitalier Pitié-Salpêtrière, 75013 Paris, France.
Papers in Europe PMC - 03Marzano AV4 papers · 2022
Department of Pathophysiology and Transplantation, University of Milan, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Italy. angelovalerio.marzano@policlinico.mi.it
Papers in Europe PMC - 04André M3 papers · 2022
Department of Internal Medicine, University Hospital Gabriel Montpied, Clermont-Ferrand, France.
Papers in Europe PMC - 05André MF3 papers · 2014
Inserm, U931, GReD, Faculté de Médecine, Clermont-Ferrand, France. mandre@chu-clermontferrand.fr
Papers in Europe PMC - 06Grateau G3 papers · 2018
Service de médecine interne, université Paris 6, Pierre-et-Marie-Curie (UPMC), hôpital Tenon, Assistance publique-Hôpitaux de Paris (AP-HP), 20, rue de la Chine, 75020 Paris, France; Inserm UMRS_933, université Pierre-et-Marie-Curie (UPMC)-Paris 6, hôpital Trousseau, Assistance publique-Hôpitaux de Paris, 75012 Paris, France; Centre de référence des maladies auto-inflammatoires et de l'amylose inflammatoire (CEREMAIA), 75020 Paris, France.
Papers in Europe PMC - 07Alaibac M2 papers · 2023
Dermatology Unit, Department of Medicine, University of Padova, I-35128 Padova, Italy.
Papers in Europe PMC - 08Andre M2 papers · 2023
Inserm U1071, M2iSH, USC-INRA 1382, Université Clermont Auvergne, Clermont-Ferrand, Auvergne-Rhône-Alpes, France.
Papers in Europe PMC - 09Aumaitre O2 papers · 2022
Médecine Interne, CHU Gabriel Montpied, 63000 Clermont-Ferrand, France.
Papers in Europe PMC - 10Cardoso MC2 papers · 2010Papers in Europe PMC
Clinical research
Is a treatment being tested?
1
interventional trials for this specific condition
1 interventional trial matched this specific condition name; none in our sample are currently recruiting.
Data as of 27 July 2026
1 interventional trial — more than 73% of diseases in the trials denominator have none at all (5114 of 7003; this disease is at the 76.8th percentile).
high confidence · 76.8th percentile (trials denominator)
Recruiting interventional trials
From the matched ClinicalTrials.gov set
1 interventional trials matched after quoted-phrase search and title/condition post-filter.
No currently recruiting studies in the matched set. Open the same search on ClinicalTrials.gov.
Where to find support
We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:
India — NPRD
Last verified 2026-07-26This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.
Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.
How we counted this
Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored on the overview but are not added to the query string.
"Aseptic abscess syndrome" OR "Aseptic abscesses syndrome" OR "Aseptic systemic abscesses" OR "Corticosteroid-sensitive aseptic abscess syndrome" OR "Disseminated aseptic abscesses"
ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):
"Aseptic abscess syndrome" OR "Aseptic abscesses syndrome" OR "Aseptic systemic abscesses" OR "Corticosteroid-sensitive aseptic abscess syndrome" OR "Disseminated aseptic abscesses"
Interventional trials matched via: phrase (mesh = registered under a MeSH descriptor no name phrase would catch; recall-expansion = gene / selected parent terms used only for trials).
Study-type breakdown: 1 interventional · 0 observational · 0 expanded access. Only interventional studies enter the trial headline.
Query health: ok — strategies attempted: phrase; with hits: phrase
Run this search on ClinicalTrials.gov
Confidence reasoning
- Preferred label is multi-word and distinctive
- No synonyms dropped by stoplist
- No label/synonym collisions with other diseases in this corpus
Ingested 2026-07-27T00:55:49.703Z