ORPHA:439755
Single-organ polyarteritis nodosa
Also known as: Single-organ PAN · Single-organ periarteritis nodosa
Query health: suspect — Only one of 2 strategies returned hits (phrase).
Clinical definition (Orphanet)
Single-organ polyarteritis nodosa (PAN) is a rare, often mild form of PAN characterized by limited disease without generalized manifestations, most often affecting the skin (cutaneous PAN), the brain, eyes, pancreas, testicles, ureter, breasts, or ovaries. Affected patients are often younger than those with systemic PAN and relapses appear to be more common.
Is anyone studying this?
6
6 papers have ever been indexed under this name. For scale, breast cancer has over 700,000. Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=183) is 38.
6 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 38 (publications denominator n=183).
4 in the last 10 years · high confidence · 20.5th percentile (publications denominator)
Is a treatment being tested?
0
trials for this specific condition
No interventional trial testing a treatment matched this specific condition name on ClinicalTrials.gov (observational studies and pan-disease registries are listed separately when present). 9 trials are registered for polyarteritis nodosa, the broader category — shown separately because they may or may not enrol this specific subtype.
Data as of 26 July 2026
9
trials for polyarteritis nodosa, the broader category this belongs to
Trials registered for a broader category may or may not enrol people with this specific subtype — eligibility criteria vary, and the trial record often doesn't say. Worth raising with a clinician. How we count trials.
No matched interventional trials. This is true for 59.2% of diseases in the trials denominator (151 of 255). Here are the researchers publishing on it.
high confidence · 29.6th percentile (trials denominator)
Do we know what causes it?
Not yet — the cause hasn't been pinned down in GenCC.
No strong gene–disease assertion joined for this Orphanet entity.
Who's working on it?
23
Distinct author names in 6 sampled papers — named people below.
Who's working on it?
No interventional trial matched this name; these authors publish on it in the sampled literature — a practical starting point for contact.
- 01Akgul M1 paper · 2026
Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA; Department of Pathology, Atlas University School of Medicine, Istanbul, Turkey. Electronic address: makgul@bwh.harvard.edu.
Papers in Europe PMC - 02Anderson BE1 paper · 2018
Department of Dermatology, Penn State Health Hershey Medical Center, Hershey, Pennsylvania.
Papers in Europe PMC - 03Cartee T1 paper · 2018
Department of Dermatology, Penn State Health Hershey Medical Center, Hershey, Pennsylvania.
Papers in Europe PMC - 04Dehghan N1 paper · 2019
Division of Rheumatology, Department of Medicine, University of British Columbia, Vancouver, Canada.
Papers in Europe PMC - 05Ergas D1 paper · 2002Papers in Europe PMC
- 06Fraenkel-Rubin M1 paper · 2002
Department of Medicine B, Kaplan Medical Centre, Rehovot, Israel.
Papers in Europe PMC - 07
- 08Gago R1 paper · 2017
Division of Rheumatology, Department of Medicine, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico.
Papers in Europe PMC - 09Helm KF1 paper · 2018
Department of Dermatology, Penn State Health Hershey Medical Center, Hershey, Pennsylvania.
Papers in Europe PMC - 10Helm MF1 paper · 2018
Department of Dermatology, Penn State Health Hershey Medical Center, Hershey, Pennsylvania.
Papers in Europe PMC
Recruiting interventional trials
Trials testing a treatment from the matched ClinicalTrials.gov set
No interventional trial testing a treatment was found for this specific condition name on ClinicalTrials.gov.
9 interventional trials matched polyarteritis nodosa, the broader category — see the summary above. Those studies are not counted in the condition-specific total.
Where to find support
We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:
India — NPRD
Last verified 2026-07-26This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.
Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.
How we counted this
Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored below but are not added to the query string.
"Single-organ polyarteritis nodosa" OR "Single-organ PAN" OR "Single-organ periarteritis nodosa"
ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):
"Single-organ polyarteritis nodosa" OR "Single-organ PAN" OR "Single-organ periarteritis nodosa" OR "primary polyarteritis nodosa"
Study-type breakdown: 0 interventional · 0 observational · 0 expanded access. Only interventional studies enter the trial headline.
Cross-references (from Mondo): UMLS:C5680051
Query health: suspect — strategies attempted: phrase, recall-expansion; with hits: phrase
Run this search on ClinicalTrials.gov
Confidence reasoning
- Preferred label is multi-word and distinctive
- No synonyms dropped by stoplist
- No label/synonym collisions with other diseases in this corpus