ORPHA:33475
Meningococcal meningitis
Publications
6,479
Trials
64
Interventional, condition-specific
Researchers
1,072
Distinct authors in sample
Gene link
—
Readiness
2/6
Stages with a signal
Cross-references
Joined from Mondo / Orphanet. MeSH labels may enter searches; UMLS / OMIM / NCIT are stored for reference.
- MONDO:0018059
- MeSH:D008585
- UMLS:C0025294
Research stages
Trial readiness signals
Where this condition sits on an open-data research pipeline — not how close a treatment is, and not medical advice. Empty stages often mean “not in these databases under this Mondo ID,” not “impossible.”
2/6 stages with a signal
An interventional trial matched this condition name on ClinicalTrials.gov — see trials below.
- Gene identifiedNot found
No GenCC disease–gene assertion in this build
- LiteraturePresent
6,479 matched papers (2,096 in last 10 years) Source
- Phenotype characterisedNot checked
Not yet enriched from Monarch / HPO
- Animal modelNot checked
Not yet enriched from Monarch / Alliance
- Orphan designationNot checked
FDA/EMA orphan-drug designation not enriched yet
- Interventional trialPresent
64 matched on ClinicalTrials.gov (2 recruiting in sample)
Biology
Genes and phenotypes
Gene–disease validity from GenCC, plus phenotypes and animal models joined from Monarch Initiative via Mondo ID — not a clinical diagnosis aid.
Do we know what causes it?
Not yet — the cause hasn't been pinned down in GenCC.
No strong gene–disease assertion joined for this Orphanet entity.
Phenotypes (Monarch / HPO)
Not enriched in this build — Monarch phenotype joins were not run for this record.
Animal models (Monarch / Alliance)
Not enriched in this build.
Literature
Is anyone studying this?
6,479
6,479 papers — among the better-studied rare conditions, though still a fraction of common-disease literature (breast cancer: over 700,000). Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=5449) is 41.
6,479 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 41 (publications denominator n=5449).
2,096 in the last 10 years · low confidence
Phrase hits: 6,479 · MeSH hits: 0
Who's working on it?
1,072
Distinct author names in 200 sampled papers — named people below.
Who's working on it?
People publishing on this condition (sampled Europe PMC records). Affiliation is the most recent found in that sample.
- 01Delport D4 papers · 2026
Burnet Institute, Melbourne, Victoria, Australia dominic.delport@burnet.edu.au.
Papers in Europe PMC - 02Li M4 papers · 2026
Sichuan Center for Disease Control and Prevention, Chengdu, 610041, Sichuan Province, China.
Papers in Europe PMC - 03Liu Y4 papers · 2026
Department of Expanded Program on Immunization, Hangzhou Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.
Papers in Europe PMC - 04
- 05
- 06Brouwer MC3 papers · 2025
Department of Neurology, Amsterdam Neuroscience, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Papers in Europe PMC - 07Liu J3 papers · 2025
Institute of Child and Adolescent Health, School of Public Health, National Health Commission Key Laboratory of Reproductive Health, Peking University, Beijing, China.
Papers in Europe PMC - 08Muellenmeister AM3 papers · 2026
Burnet Institute, Melbourne, Victoria, Australia.
Papers in Europe PMC - 09Song Y3 papers · 2025
Institute of Child and Adolescent Health, School of Public Health, National Health Commission Key Laboratory of Reproductive Health, Peking University, Beijing, China.
Papers in Europe PMC - 10van de Beek D3 papers · 2025
Department of Neurology, Amsterdam Neuroscience, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Papers in Europe PMC
Clinical research
Is a treatment being tested?
64
interventional trials for this specific condition
64 interventional trials matched this specific condition name; 2 currently recruiting in our sample.
Data as of 27 July 2026
64 interventional trials — more than 73% of diseases in the trials denominator have none at all (5114 of 7003; this disease is at the 97.7th percentile).
low confidence · 97.7th percentile (trials denominator)
Recruiting interventional trials
From the matched ClinicalTrials.gov set
64 interventional trials matched after quoted-phrase search and title/condition post-filter.
- NCT07374510·NOT YET RECRUITING·Phase Ia Clinical Trial of Group ACYW135X Meningococcal Conjugate Vaccine
Conditions: Meningococcal Meningitis·Matched via name phrase
- NCT06832514·RECRUITING·Investigating Gender and Sex Differences in Immune Responses Through Vaccination of Transgender and Cisgender Persons
Conditions: Meningococcal Meningitis, Serogroup B · Transgender Persons · Sex Differences in Immune Response · Vaccination·Matched via name phrase
Observational and natural-history studies
3 observational studies match this condition. These do not test a treatment and are not counted in the interventional-trial headline, but they are genuine research: natural-history work often defines the endpoints needed for a future rare-disease trial, and families may be able to enroll.
None of the matched observational studies is currently listed as recruiting.
Where to find support
We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:
India — NPRD
Last verified 2026-07-26This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.
Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.
How we counted this
Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored on the overview but are not added to the query string.
"Meningococcal meningitis"
ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):
"Meningococcal meningitis"
Interventional trials matched via: phrase (mesh = registered under a MeSH descriptor no name phrase would catch; recall-expansion = gene / selected parent terms used only for trials).
Study-type breakdown: 64 interventional · 3 observational · 0 expanded access. Only interventional studies enter the trial headline.
Query health: ok — strategies attempted: phrase; with hits: phrase
Run this search on ClinicalTrials.gov
Confidence reasoning
- Preferred label is multi-word and distinctive
- No synonyms dropped by stoplist
- No label/synonym collisions with other diseases in this corpus
- Publication count (6479) is extremely high with unknown/missing prevalence — treat as possible over-matching, not proven research intensity
Ingested 2026-07-26T23:36:58.569Z