ORPHA:3283
His bundle tachycardia
Also known as: JET · Junctional ectopic tachycardia
Clinical definition (Orphanet)
His bundle tachycardia is a very rare genetic tachyarrhythmia characterized by incessant tachycardia and high morbidity and mortality.
How rare: How common this is has not been clearly measured.
Is anyone studying this?
926
926 papers have been published on this condition. That is a real research literature — still far smaller than common diseases (breast cancer: over 700,000 papers). Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=183) is 38.
926 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 38 (publications denominator n=183).
469 in the last 10 years · medium confidence · 90.4th percentile (publications denominator)
Is a treatment being tested?
1
trials for this specific condition
1 interventional trial matched this specific condition name; none in our sample are currently recruiting.
Data as of 26 July 2026
1 interventional trial — more than 59.2% of diseases in the trials denominator have none at all (151 of 255; this disease is at the 65.3th percentile).
medium confidence · 65.3th percentile (trials denominator)
Do we know what causes it?
Not yet — the cause hasn't been pinned down in GenCC.
No strong gene–disease assertion joined for this Orphanet entity.
Who's working on it?
1,045
Distinct author names in 200 sampled papers — named people below.
Who's working on it?
People publishing on this condition (sampled Europe PMC records). Affiliation is the most recent found in that sample.
- 01
- 02Aoki H3 papers · 2026
Department of Pediatric Cardiology, Osaka Women's and Children's Hospital, 840 Murodo-cho, Izumi, Osaka 594-1101, Japan.
Papers in Europe PMC - 03
- 04Dasgupta S3 papers · 2023
Department of Cardiology, Boston Children's Hospital, Boston, Massachusetts.
Papers in Europe PMC - 05Dionne A3 papers · 2025
Department of Cardiology, Boston Children's Hospital, Boston, Massachusetts; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts.
Papers in Europe PMC - 06
- 07Haydin S3 papers · 2024
Department of Pediatric Cardiovascular Surgery, University of Health Sciences, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.
Papers in Europe PMC - 08Kaseno K3 papers · 2025
Division of Cardiology Gunma Prefectural Cardiovascular Center Maebashi Japan.
Papers in Europe PMC - 09Naito S3 papers · 2025
Division of Cardiology Gunma Prefectural Cardiovascular Center Maebashi Japan.
Papers in Europe PMC - 10Nakamura K3 papers · 2025
Division of Cardiology Gunma Prefectural Cardiovascular Center Maebashi Japan.
Papers in Europe PMC
Recruiting interventional trials
Trials testing a treatment from the matched ClinicalTrials.gov set
1 interventional trials matched after quoted-phrase search and title/condition post-filter.
No currently recruiting studies in the matched set. Open the same search on ClinicalTrials.gov.
Where to find support
We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:
India — NPRD
Last verified 2026-07-26This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.
Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.
How we counted this
Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored below but are not added to the query string.
"His bundle tachycardia" OR "Junctional ectopic tachycardia"
MeSH descriptor terms unioned into the query: Tachycardia, Ectopic Junctional
ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):
"His bundle tachycardia" OR "Junctional ectopic tachycardia" OR "Tachycardia, Ectopic Junctional"
Interventional trials matched via: phrase (mesh = registered under a MeSH descriptor no name phrase would catch; recall-expansion = gene / selected parent terms used only for trials).
Study-type breakdown: 1 interventional · 0 observational · 0 expanded access. Only interventional studies enter the trial headline.
Cross-references (from Mondo): MESH:D013613 UMLS:C0039235 NCIT:C111646
Query health: ok — strategies attempted: phrase, mesh; with hits: phrase, mesh
Run this search on ClinicalTrials.gov
Synonyms dropped by stoplist: JET
Confidence reasoning
- Preferred label is multi-word and distinctive
- 1 synonym(s) dropped by stoplist (may under-count)
- No label/synonym collisions with other diseases in this corpus