RARE DISEASERESEARCH ATLAS

ORPHA:319254

Kyasanur forest disease

low confidenceDisorder

Also known as: Kyasanur hemorrhagic fever · Monkey disease · Monkey fever

Publications

2,526

Trials

0

Interventional, condition-specific

Researchers

997

Distinct authors in sample

Gene link

Readiness

1/6

Stages with a signal

Clinical definition (Orphanet)

A rare infectious disease caused by the kyasanura forest disease virus and clinically characterized by an initial fever, headache and myalgia that can progress to a hemorrhagic disease and that in some cases is followed by a second phase characterized by neurological manifestations.

Orphanet entry

Cross-references

Joined from Mondo / Orphanet. MeSH labels may enter searches; UMLS / OMIM / NCIT are stored for reference.

Additional Mondo synonyms (3)

Kyasanur forest disease virus caused disease or disorder · Kyasanur forest disease virus disease or disorder · Kyasanur forest disease virus infectious disease

Research stages

Trial readiness signals

Where this condition sits on an open-data research pipeline — not how close a treatment is, and not medical advice. Empty stages often mean “not in these databases under this Mondo ID,” not “impossible.”

1/6 stages with a signal

Research-stage checklist from open sources (GenCC, literature, Monarch when enriched, ClinicalTrials.gov). Not a prognosis or care recommendation.

  1. Gene identifiedNot found

    No GenCC disease–gene assertion in this build

  2. LiteraturePresent

    2,526 matched papers (1,415 in last 10 years) Source

  3. Phenotype characterisedNot checked

    Not yet enriched from Monarch / HPO

  4. Animal modelNot checked

    Not yet enriched from Monarch / Alliance

  5. Orphan designationNot checked

    FDA/EMA orphan-drug designation not enriched yet

  6. Interventional trialNot found

    No matched interventional trial under our ClinicalTrials.gov rules

Biology

Genes and phenotypes

Gene–disease validity from GenCC, plus phenotypes and animal models joined from Monarch Initiative via Mondo ID — not a clinical diagnosis aid.

Do we know what causes it?

Not yet — the cause hasn't been pinned down in GenCC.

No strong gene–disease assertion joined for this Orphanet entity.

Phenotypes (Monarch / HPO)

Not enriched in this build — Monarch phenotype joins were not run for this record.

Animal models (Monarch / Alliance)

Not enriched in this build.

Literature

Is anyone studying this?

2,526

2,526 papers have been published on this condition. That is a real research literature — still far smaller than common diseases (breast cancer: over 700,000 papers). Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=5449) is 41.

2,526 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 41 (publications denominator n=5449).

1,415 in the last 10 years · low confidence

Phrase hits: 2,526 · MeSH hits: 82

Open Europe PMC search

Who's working on it?

997

Distinct author names in 200 sampled papers — named people below.

Who's working on it?

No interventional trial matched this name; these authors publish on it in the sampled literature — a practical starting point for contact.

  1. 01
    Gupta N24 papers · 2026

    Indian Council of Medical Research, New Delhi, India. drguptanivedita@gmail.com.

    Papers in Europe PMC
  2. 02
    Varma M8 papers · 2026

    Department of Infectious Diseases, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Madhavnagar, Manipal 576104, India.

    Papers in Europe PMC
  3. 03
    Mukhopadhyay C7 papers · 2026

    Department of Microbiology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.

    Papers in Europe PMC
  4. 04
    Yadav P7 papers · 2025

    ICMR-National Institute of Virology, 20-A, Dr. Ambedkar Road, Pune, Maharashtra, 411021 India. Electronic address: hellopragya22@gmail.com.

    Papers in Europe PMC
  5. 05
    Elango A6 papers · 2026

    Division of Vector Biology and Control, ICMR-Vector Control Research Centre, Department of Health Research, Ministry of Health & Family Welfare, GOI, Medical Complex, Indira Nagar, Puducherry 605 006, India.

    Papers in Europe PMC
  6. 06
    Yadav PD6 papers · 2026

    Maximum Containment Facility, ICMR-National Institute of Virology, Pune, Maharashtra, India.

    Papers in Europe PMC
  7. 07
    Kumar R5 papers · 2026

    Regional Health Office, Bangalore, Government of India.

    Papers in Europe PMC
  8. 08
    Patil DY5 papers · 2026

    Maximum Containment Facility, ICMR-National Institute of Virology, Pune, Maharashtra, India.

    Papers in Europe PMC
  9. 09
    Purse BV5 papers · 2025

    UK Centre for Ecology & Hydrology, Wallingford, United Kingdom

    Papers in Europe PMC
  10. 10
    Rahi M5 papers · 2026

    Division of Epidemiology and Communicable Diseases, Indian Council of Medical Research, New Delhi, India.

    Papers in Europe PMC

Clinical research

Is a treatment being tested?

0

interventional trials for this specific condition

No interventional trial testing a treatment matched this specific condition name on ClinicalTrials.gov (observational studies and pan-disease registries are listed separately when present).

Data as of 27 July 2026

No matched interventional trials. This is true for 73% of diseases in the trials denominator (5114 of 7003). Here are the researchers publishing on it.

low confidence · 36.5th percentile (trials denominator)

Recruiting interventional trials

From the matched ClinicalTrials.gov set

No interventional trial testing a treatment was found for this specific condition name on ClinicalTrials.gov.

See who's working on it — people publishing on this disease are often the practical next contact when no trial is listed.

Where to find support

We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:

India — NPRD

Last verified 2026-07-26

This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.

Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.

How we counted this

Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored on the overview but are not added to the query string.

"Kyasanur forest disease" OR "Kyasanur hemorrhagic fever" OR "Monkey disease" OR "Monkey fever" OR "Kyasanur forest disease virus infectious disease"

Run this search on Europe PMC

MeSH descriptor terms unioned into the query: Kyasanur Forest Disease

ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):

"Kyasanur forest disease" OR "Kyasanur hemorrhagic fever" OR "Monkey disease" OR "Monkey fever" OR "Kyasanur forest disease virus infectious disease"

Study-type breakdown: 0 interventional · 0 observational · 0 expanded access. Only interventional studies enter the trial headline.

Query health: ok — strategies attempted: phrase, mesh; with hits: phrase, mesh

Run this search on ClinicalTrials.gov

Synonyms dropped by stoplist: Kyasanur forest disease virus caused disease or disorder; Kyasanur forest disease virus disease or disorder

Confidence reasoning

  • Preferred label is multi-word and distinctive
  • No synonyms dropped by stoplist
  • No label/synonym collisions with other diseases in this corpus
  • Publication count (2526) is extremely high with unknown/missing prevalence — treat as possible over-matching, not proven research intensity

Ingested 2026-07-27T13:21:21.065Z