ORPHA:280315
Autoimmune pancreatitis type 2
Also known as: AIP type 2 · Duct-centric pancreatitis
Query health: suspect — Only one of 2 strategies returned hits (phrase).
Publications
342
81.3th percentile
Trials
0
Interventional, condition-specific
Researchers
1,067
Distinct authors in sample
Gene link
—
Readiness
2/6
Stages with a signal
Clinical definition (Orphanet)
Type 2 autoimmune pancreatitis is a form of autoimmune pancreatitis affecting both sexes and having a younger age of onset (<60 years) and presenting with abdominal pain, steatorrhea and obstructive jaundice.
How rare: 1-9 / 1 000 000 — roughly one to nine people per million. In a city the size of Kolkata, perhaps a few dozen.
Cross-references
Joined from Mondo / Orphanet. MeSH labels may enter searches; UMLS / OMIM / NCIT are stored for reference.
- MONDO:0017228
- UMLS:C5197785
Additional Mondo synonyms (1)
duct-centric pancreatitis
Research stages
Trial readiness signals
Where this condition sits on an open-data research pipeline — not how close a treatment is, and not medical advice. Empty stages often mean “not in these databases under this Mondo ID,” not “impossible.”
2/6 stages with a signal
No specific-condition interventional trial, but broader-category trials exist — discuss eligibility with a clinician.
- Gene identifiedNot found
No GenCC disease–gene assertion in this build
- LiteraturePresent
342 matched papers (239 in last 10 years) Source
- Phenotype characterisedNot checked
Not yet enriched from Monarch / HPO
- Animal modelNot checked
Not yet enriched from Monarch / Alliance
- Orphan designationNot checked
FDA/EMA orphan-drug designation not enriched yet
- Interventional trialPartial
None under the specific name; 8 for broader category autoimmune pancreatitis
Biology
Genes and phenotypes
Gene–disease validity from GenCC, plus phenotypes and animal models joined from Monarch Initiative via Mondo ID — not a clinical diagnosis aid.
Do we know what causes it?
Not yet — the cause hasn't been pinned down in GenCC.
No strong gene–disease assertion joined for this Orphanet entity.
Phenotypes (Monarch / HPO)
Not enriched in this build — Monarch phenotype joins were not run for this record.
Animal models (Monarch / Alliance)
Not enriched in this build.
Literature
Is anyone studying this?
342
342 papers have ever been published on this condition (under this name). For scale, breast cancer has over 700,000. Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=5449) is 41.
342 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 41 (publications denominator n=5449).
239 in the last 10 years · high confidence · 81.3th percentile (publications denominator)
Phrase hits: 342 · MeSH hits: 0
Who's working on it?
1,067
Distinct author names in 200 sampled papers — named people below.
Who's working on it?
No interventional trial matched this name; these authors publish on it in the sampled literature — a practical starting point for contact.
- 01Löhr JM13 papers · 2026
Department for Upper Abdominal Diseases, Karolinska University Hospital, Stockholm, Sweden.
Papers in Europe PMC - 02Vujasinovic M13 papers · 2026
Department of Medicine Huddinge, Karolinska Institute, Stockholm, Sweden.
Papers in Europe PMC - 03Kim MH6 papers · 2019
Jong Wook Kim, Department of Internal Medicine, Inje University Ilsan Paik Hospital, Goyang 10380, South Korea.
Papers in Europe PMC - 04Nikolic S6 papers · 2025
Department of Gastroenterology, Clinic of Internal Medicine, University Medical Centre Maribor, Maribor, Slovenia.
Papers in Europe PMC - 05Frulloni L5 papers · 2024
Department of Medicine, Pancreas Center, University of Verona, Italy.
Papers in Europe PMC - 06Jin Z5 papers · 2026
1Department of Gastroenterology, National Clinical Research Center for Digestive Diseases, Changhai Hospital; National Key Laboratory of Immunity and Inflammation, Naval Medical University, Shanghai 200433, China.
Papers in Europe PMC - 07Okazaki K5 papers · 2022
Department of Gastroenterology and Hepatology, Kansai Medical University, Japan. Electronic address: okazaki@hirakata.kmu.ac.jp.
Papers in Europe PMC - 08Zen Y5 papers · 2022
Division of Diagnostic Pathology, Kobe University Graduate School of Medicine, Kobe, Japan.
Papers in Europe PMC - 09de Pretis N4 papers · 2024
Gastroenterology Unit, Pancreas Center, University of Verona, Piazzale L.A. Scuro 10, 37134, Verona, Italy. Electronic address: nic_depretis@yahoo.it.
Papers in Europe PMC - 10Huang H4 papers · 2026
1Department of Gastroenterology, National Clinical Research Center for Digestive Diseases, Changhai Hospital; National Key Laboratory of Immunity and Inflammation, Naval Medical University, Shanghai 200433, China.
Papers in Europe PMC
Clinical research
Is a treatment being tested?
0
interventional trials for this specific condition
No interventional trial testing a treatment matched this specific condition name. 1 observational study did — shown below because natural-history and cohort work can be an important step toward a trial. 8 trials are registered for autoimmune pancreatitis, the broader category — shown separately because they may or may not enrol this specific subtype.
Data as of 27 July 2026
No matched interventional trials. This is true for 73% of diseases in the trials denominator (5114 of 7003). Here are the researchers publishing on it.
high confidence · 36.5th percentile (trials denominator)
Recruiting interventional trials
From the matched ClinicalTrials.gov set
No interventional trial testing a treatment was found for this specific condition name on ClinicalTrials.gov.
8 interventional trials matched autoimmune pancreatitis, the broader category — listed below. Those studies are not counted in the condition-specific total.
Broader category: autoimmune pancreatitis
8
Interventional trials for the parent category, exclusive of NCT IDs already counted above. Eligibility for this subtype is not guaranteed.
Worth raising with a clinician. How we count trials.
Recruiting under the broader category
- NCT06753318·NOT YET RECRUITING·Validation of Joint-AI in Diagnosing Pancreatic Solid Lesions
Conditions: Pancreatic Cancer · Pancreatitis · Pancreatic Neuroendocine Neoplasms (pNETs) · Autoimmune Pancreatitis·Matched via name phrase
Observational and natural-history studies
1 observational study matches this condition. These do not test a treatment and are not counted in the interventional-trial headline, but they are genuine research: natural-history work often defines the endpoints needed for a future rare-disease trial, and families may be able to enroll.
None of the matched observational studies is currently listed as recruiting.
Where to find support
We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:
India — NPRD
Last verified 2026-07-26This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.
Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.
How we counted this
Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored on the overview but are not added to the query string.
"Autoimmune pancreatitis type 2" OR "AIP type 2" OR "Duct-centric pancreatitis"
ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):
"Autoimmune pancreatitis type 2" OR "AIP type 2" OR "Duct-centric pancreatitis" OR "autoimmune disorder of endocrine system" OR "autoimmune disorder of gastrointestinal tract"
Recall-expansion terms: autoimmune disorder of endocrine system, autoimmune disorder of gastrointestinal tract
Study-type breakdown: 0 interventional · 1 observational · 0 expanded access. Only interventional studies enter the trial headline.
Parent-category trials query:
"autoimmune pancreatitis"
Query health: suspect — strategies attempted: phrase, recall-expansion; with hits: phrase
Run this search on ClinicalTrials.gov
Confidence reasoning
- Preferred label is multi-word and distinctive
- No synonyms dropped by stoplist
- No label/synonym collisions with other diseases in this corpus
Ingested 2026-07-27T11:52:51.203Z