RARE DISEASERESEARCH ATLAS

ORPHA:263310

Thymoma type A

medium confidenceSubtype of disorder

Publications

653

87.9th percentile

Trials

0

Interventional, condition-specific

Researchers

1,117

Distinct authors in sample

Gene link

Readiness

2/6

Stages with a signal

How rare: How common this is has not been clearly measured.

Orphanet entry

Cross-references

Joined from Mondo / Orphanet. MeSH labels may enter searches; UMLS / OMIM / NCIT are stored for reference.

Additional Mondo synonyms (6)

medullary thymoma · primary thymic epithelial neoplasm type A · primary thymic epithelial tumor type A · primary thymic epithelial tumour type A · spindle cell thymoma · thymoma type A

Research stages

Trial readiness signals

Where this condition sits on an open-data research pipeline — not how close a treatment is, and not medical advice. Empty stages often mean “not in these databases under this Mondo ID,” not “impossible.”

2/6 stages with a signal

No specific-condition interventional trial, but broader-category trials exist — discuss eligibility with a clinician.

  1. Gene identifiedNot found

    No GenCC disease–gene assertion in this build

  2. LiteraturePresent

    653 matched papers (390 in last 10 years) Source

  3. Phenotype characterisedNot checked

    Not yet enriched from Monarch / HPO

  4. Animal modelNot checked

    Not yet enriched from Monarch / Alliance

  5. Orphan designationNot checked

    FDA/EMA orphan-drug designation not enriched yet

  6. Interventional trialPartial

    None under the specific name; 74 for broader category thymoma

Biology

Genes and phenotypes

Gene–disease validity from GenCC, plus phenotypes and animal models joined from Monarch Initiative via Mondo ID — not a clinical diagnosis aid.

Do we know what causes it?

Not yet — the cause hasn't been pinned down in GenCC.

No strong gene–disease assertion joined for this Orphanet entity.

Phenotypes (Monarch / HPO)

Not enriched in this build — Monarch phenotype joins were not run for this record.

Animal models (Monarch / Alliance)

Not enriched in this build.

Literature

Is anyone studying this?

653

653 papers have been published on this condition. That is a real research literature — still far smaller than common diseases (breast cancer: over 700,000 papers). Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=5449) is 41.

653 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 41 (publications denominator n=5449).

390 in the last 10 years · medium confidence · 87.9th percentile (publications denominator)

Phrase hits: 653 · MeSH hits: 0

Open Europe PMC search

Who's working on it?

1,117

Distinct author names in 200 sampled papers — named people below.

Who's working on it?

No interventional trial matched this name; these authors publish on it in the sampled literature — a practical starting point for contact.

  1. 01
    Zhang J7 papers · 2026

    School of Pet Science and Technology, Jiangsu Agricultural and Animal Husbandry Technology Vocational College, Taizhou, China.

    Papers in Europe PMC
  2. 02
    Moran CA6 papers · 2026

    Department of Pathology, MD Anderson Cancer Center, Houston, TX 77030.

    Papers in Europe PMC
  3. 03
    Weissferdt A6 papers · 2026

    Department of Pathology, MD Anderson Cancer Center, Houston, TX 77030, USA. aweissferdt@doctors.org.uk

    Papers in Europe PMC
  4. 04
    Wang L5 papers · 2024

    Department of Pathology, First Hospital of China Medical University, Shenyang, China.

    Papers in Europe PMC
  5. 05
    Liu J4 papers · 2026

    School of Computer and Information Technology, Beijing Jiaotong University, Beijing, China.

    Papers in Europe PMC
  6. 06
    Liu Y4 papers · 2025

    Department of Hematology-Oncology, Chongqing University Cancer Hospital, No.181 HanYu Road, Chongqing, 400030, China. liuyao77@cqu.edu.cn.

    Papers in Europe PMC
  7. 07
    Suster S4 papers · 2025

    Department of Pathology, Medical College of Wisconsin, Milwaukee, WI.

    Papers in Europe PMC
  8. 08
    Chen H3 papers · 2024

    Department of Pathology, China-Japan Friendship Hospital, Beijing, China.

    Papers in Europe PMC
  9. 09
    Chen L3 papers · 2026

    Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 156 Wujiadun, Jianghan District, Wuhan, Hubei Province, 430022, China.

    Papers in Europe PMC
  10. 10
    Li J3 papers · 2024

    Department of Hematology-Oncology, Chongqing University Cancer Hospital, No.181 HanYu Road, Chongqing, 400030, China.

    Papers in Europe PMC

Clinical research

Is a treatment being tested?

0

interventional trials for this specific condition

No interventional trial testing a treatment matched this specific condition name on ClinicalTrials.gov (observational studies and pan-disease registries are listed separately when present). 74 trials are registered for thymoma, the broader category — shown separately because they may or may not enrol this specific subtype.

Data as of 27 July 2026

No matched interventional trials. This is true for 73% of diseases in the trials denominator (5114 of 7003). Here are the researchers publishing on it.

medium confidence · 36.5th percentile (trials denominator)

Recruiting interventional trials

From the matched ClinicalTrials.gov set

No interventional trial testing a treatment was found for this specific condition name on ClinicalTrials.gov.

74 interventional trials matched thymoma, the broader category — listed below. Those studies are not counted in the condition-specific total.

Broader category: thymoma

74

Interventional trials for the parent category, exclusive of NCT IDs already counted above. Eligibility for this subtype is not guaranteed.

Worth raising with a clinician. How we count trials.

Recruiting under the broader category

Where to find support

We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:

India — NPRD

Last verified 2026-07-26

This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.

Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.

How we counted this

Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored on the overview but are not added to the query string.

"Thymoma type A" OR "medullary thymoma" OR "primary thymic epithelial neoplasm type A" OR "primary thymic epithelial tumor type A" OR "primary thymic epithelial tumour type A" OR "spindle cell thymoma"

Run this search on Europe PMC

ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):

"Thymoma type A" OR "medullary thymoma" OR "primary thymic epithelial neoplasm type A" OR "primary thymic epithelial tumor type A" OR "primary thymic epithelial tumour type A" OR "spindle cell thymoma"

Study-type breakdown: 0 interventional · 0 observational · 0 expanded access. Only interventional studies enter the trial headline.

Parent-category trials query:

"thymoma"

Query health: ok — strategies attempted: phrase; with hits: phrase

Run this search on ClinicalTrials.gov

Confidence reasoning

  • Preferred label is short or not clearly distinctive
  • No synonyms dropped by stoplist
  • No label/synonym collisions with other diseases in this corpus

Ingested 2026-07-27T11:18:53.305Z