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ORPHA:254478

Lichen planus pemphigoides

medium confidenceDisorder

Also known as: LP pemphigoides

Query health: suspect — Only one of 2 strategies returned hits (phrase).

Publications

414

83.1th percentile

Trials

0

Interventional, condition-specific

Researchers

918

Distinct authors in sample

Gene link

—

Readiness

2/6

Stages with a signal

Clinical definition (Orphanet)

Lichen planus (LP) pemphigoides is a rare cross-over syndrome between lichen planus and bullous pemphigoid.

How rare: <1 / 1 000 000 — fewer than one in a million. In a city the size of Kolkata, that might mean on the order of fifteen people.

Orphanet entry

Cross-references

Joined from Mondo / Orphanet. MeSH labels may enter searches; UMLS / OMIM / NCIT are stored for reference.

Research stages

Trial readiness signals

Where this condition sits on an open-data research pipeline — not how close a treatment is, and not medical advice. Empty stages often mean “not in these databases under this Mondo ID,” not “impossible.”

2/6 stages with a signal

No specific-condition interventional trial, but broader-category trials exist — discuss eligibility with a clinician.

  1. Gene identifiedNot found

    No GenCC disease–gene assertion in this build

  2. LiteraturePresent

    414 matched papers (269 in last 10 years) Source

  3. Phenotype characterisedNot checked

    Not yet enriched from Monarch / HPO

  4. Animal modelNot checked

    Not yet enriched from Monarch / Alliance

  5. Orphan designationNot checked

    FDA/EMA orphan-drug designation not enriched yet

  6. Interventional trialPartial

    None under the specific name; 143 for broader category lichen planus

Biology

Genes and phenotypes

Gene–disease validity from GenCC, plus phenotypes and animal models joined from Monarch Initiative via Mondo ID — not a clinical diagnosis aid.

Do we know what causes it?

Not yet — the cause hasn't been pinned down in GenCC.

No strong gene–disease assertion joined for this Orphanet entity.

Phenotypes (Monarch / HPO)

Not enriched in this build — Monarch phenotype joins were not run for this record.

Animal models (Monarch / Alliance)

Not enriched in this build.

Literature

Is anyone studying this?

414

414 papers have ever been published on this condition (under this name). For scale, breast cancer has over 700,000. Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=5449) is 41.

414 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 41 (publications denominator n=5449).

269 in the last 10 years · medium confidence · 83.1th percentile (publications denominator)

Phrase hits: 414 · MeSH hits: 0

Open Europe PMC search

Who's working on it?

918

Distinct author names in 200 sampled papers — named people below.

Who's working on it?

No interventional trial matched this name; these authors publish on it in the sampled literature — a practical starting point for contact.

  1. 01
    Markova A4 papers · 2023

    Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

    Papers in Europe PMC
  2. 02
    Didona D3 papers · 2026

    Department of Dermatology and Allergology, Philipps University, Marburg, Germany.

    Papers in Europe PMC
  3. 03
    Hertl M3 papers · 2025

    Department of Dermatology and Allergology, Philipps-Universität, Marburg, Germany.

    Papers in Europe PMC
  4. 04
    Kumar P3 papers · 2022

    Department of Dermatology, Katihar Medical College, Katihar, Bihar, India.

    Papers in Europe PMC
  5. 05
    Li W3 papers · 2026

    Department of Respiratory and Critical Care Medicine, The Second Hospital of Jilin University, Changchun, Jilin, China.

    Papers in Europe PMC
  6. 06
    Ludwig RJ3 papers · 2025

    QIMA Life Sciences, QIMA Monasterium GmbH, Münster, Germany.

    Papers in Europe PMC
  7. 07
    Mignogna MD3 papers · 2026

    Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, via Pansini 5, 80131 Naples, Italy.

    Papers in Europe PMC
  8. 08
    Schmidt E3 papers · 2024

    Department of Dermatology, Allergology and Venerology, University of Lübeck, Lübeck, Germany.

    Papers in Europe PMC
  9. 09
    Zhang X3 papers · 2025

    Department of Oncology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.

    Papers in Europe PMC
  10. 10
    Alhumidi AA2 papers · 2025

    Department of Pathology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

    Papers in Europe PMC

Clinical research

Is a treatment being tested?

0

interventional trials for this specific condition

No interventional trial testing a treatment matched this specific condition name on ClinicalTrials.gov (observational studies and pan-disease registries are listed separately when present). 143 trials are registered for lichen planus, the broader category — shown separately because they may or may not enrol this specific subtype.

Data as of 27 July 2026

No matched interventional trials. This is true for 73% of diseases in the trials denominator (5114 of 7003). Here are the researchers publishing on it.

medium confidence · 36.5th percentile (trials denominator)

Recruiting interventional trials

From the matched ClinicalTrials.gov set

No interventional trial testing a treatment was found for this specific condition name on ClinicalTrials.gov.

143 interventional trials matched lichen planus, the broader category — listed below. Those studies are not counted in the condition-specific total.

Broader category: lichen planus

143

Interventional trials for the parent category, exclusive of NCT IDs already counted above. Eligibility for this subtype is not guaranteed.

Worth raising with a clinician. How we count trials.

Recruiting under the broader category

Where to find support

We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:

India — NPRD

Last verified 2026-07-26

This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.

Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.

How we counted this

Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored on the overview but are not added to the query string.

"Lichen planus pemphigoides" OR "LP pemphigoides"

Run this search on Europe PMC

ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):

"Lichen planus pemphigoides" OR "LP pemphigoides" OR "lichen disease"

Recall-expansion terms: lichen disease

Study-type breakdown: 0 interventional · 0 observational · 0 expanded access. Only interventional studies enter the trial headline.

Parent-category trials query:

"lichen planus"

Query health: suspect — strategies attempted: phrase, recall-expansion; with hits: phrase

Run this search on ClinicalTrials.gov

Confidence reasoning

  • Preferred label is multi-word and distinctive
  • No synonyms dropped by stoplist
  • No label/synonym collisions with other diseases in this corpus
  • Publication count (414) is high for prevalence class "<1 / 1 000 000" — confidence capped at medium

Ingested 2026-07-27T11:03:42.344Z