ORPHA:213772
Adenocarcinoma of the cervix uteri
Also known as: Cervical adenocarcinoma
Publications
11,518
98th percentile
Trials
59
Interventional, condition-specific
Researchers
1,141
Distinct authors in sample
Gene link
—
Readiness
2/6
Stages with a signal
How rare: 1-9 / 100 000 — about one to nine people per hundred thousand.
Cross-references
Joined from Mondo / Orphanet. MeSH labels may enter searches; UMLS / OMIM / NCIT are stored for reference.
- MONDO:0005153
- UMLS:C0279672
- NCIT:C4029
Additional Mondo synonyms (11)
adenocarcinoma - cervix · adenocarcinoma of cervix · adenocarcinoma of cervix uteri · adenocarcinoma of the cervix · adenocarcinoma of the cervix uteri · adenocarcinoma of the uterine cervix · adenocarcinoma of uterine cervix · cervical adenocarcinoma · cervix adenocarcinoma · cervix uteri adenocarcinoma · uterine cervix adenocarcinoma
Research stages
Trial readiness signals
Where this condition sits on an open-data research pipeline — not how close a treatment is, and not medical advice. Empty stages often mean “not in these databases under this Mondo ID,” not “impossible.”
2/6 stages with a signal
An interventional trial matched this condition name on ClinicalTrials.gov — see trials below.
- Gene identifiedNot found
No GenCC disease–gene assertion in this build
- LiteraturePresent
11,518 matched papers (6,590 in last 10 years) Source
- Phenotype characterisedNot checked
Not yet enriched from Monarch / HPO
- Animal modelNot checked
Not yet enriched from Monarch / Alliance
- Orphan designationNot checked
FDA/EMA orphan-drug designation not enriched yet
- Interventional trialPresent
59 matched on ClinicalTrials.gov (10 recruiting in sample)
Biology
Genes and phenotypes
Gene–disease validity from GenCC, plus phenotypes and animal models joined from Monarch Initiative via Mondo ID — not a clinical diagnosis aid.
Do we know what causes it?
Not yet — the cause hasn't been pinned down in GenCC.
No strong gene–disease assertion joined for this Orphanet entity.
Phenotypes (Monarch / HPO)
Not enriched in this build — Monarch phenotype joins were not run for this record.
Animal models (Monarch / Alliance)
Not enriched in this build.
Literature
Is anyone studying this?
11,518
11,518 papers — among the better-studied rare conditions, though still a fraction of common-disease literature (breast cancer: over 700,000). Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=5449) is 41.
11,518 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 41 (publications denominator n=5449).
6,590 in the last 10 years · high confidence · 98th percentile (publications denominator)
Phrase hits: 11,518 · MeSH hits: 0
Who's working on it?
1,141
Distinct author names in 200 sampled papers — named people below.
Who's working on it?
People publishing on this condition (sampled Europe PMC records). Affiliation is the most recent found in that sample.
- 01Liu Y8 papers · 2026
Department of Obstetrics and Gynecology, The 964th Hospital, Changchun, Jilin, China.
Papers in Europe PMC - 02Zhang H8 papers · 2026
Department of Radiotherapy, The First Clinical Medical College of Lanzhou University, Lanzhou, Gansu, China.
Papers in Europe PMC - 03Zhang Y8 papers · 2026
Department of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China.
Papers in Europe PMC - 04Wang Y7 papers · 2026
Pathology Department, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Papers in Europe PMC - 05Wang J6 papers · 2026
Department of Pathology, The Affiliated Hospital of Qingdao University, No. 1677 Wutaishan Road, Qingdao, 266555, Shandong, China. wangjigang@qdu.edu.cn.
Papers in Europe PMC - 06Zhang L6 papers · 2026
Department of Obstetrics, Gynecology and Reproductive Sciences, Air Force Medical University, Air Force Medical Center, PLA, Beijing, China.
Papers in Europe PMC - 07Chen L5 papers · 2026
Department of Gynecology, Fujian Maternity and Child Health Hospital, College of Clinical Medical for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Papers in Europe PMC - 08Li L5 papers · 2026
NHC Key Laboratory of Cancer Metabolism, Department of Gynecology, Fujian Cancer Hospital, Clinical Oncology School of Fujian Medical University, Fuzhou, China.
Papers in Europe PMC - 09Li Y5 papers · 2026
Department of Gynecology, The First People's Hospital of Jiande, Jiande, China.
Papers in Europe PMC - 10Wang L5 papers · 2026
Department of Obstetrics and Gynecology, The 964th Hospital, Changchun, Jilin, China.
Papers in Europe PMC
Clinical research
Is a treatment being tested?
59
interventional trials for this specific condition
59 interventional trials matched this specific condition name; 10 currently recruiting in our sample. 3,633 trials are registered for adenocarcinoma, the broader category — shown separately because they may or may not enrol this specific subtype.
Data as of 27 July 2026
59 interventional trials — more than 73% of diseases in the trials denominator have none at all (5114 of 7003; this disease is at the 97.4th percentile).
high confidence · 97.4th percentile (trials denominator)
Recruiting interventional trials
From the matched ClinicalTrials.gov set
59 interventional trials matched after quoted-phrase search and title/condition post-filter.
- NCT07020117·RECRUITING·A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors
Conditions: Urothelial Carcinoma Bladder · Triple Negative Breast Cancer (TNBC) · Hormone Receptor Positive Breast Adenocarcinoma · Non Small Cell Lung Cancer·Matched via name phrase
- NCT07061977·RECRUITING·Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer
Conditions: Locally Advanced Cervical Adenocarcinoma · Locally Advanced Cervical Adenosquamous Carcinoma · Locally Advanced Cervical Squamous Cell Carcinoma · Stage IIIA Cervical Cancer FIGO 2018·Matched via name phrase
- NCT06805864·NOT YET RECRUITING·Pembrolizumab Concurrent With and Following Carbon-ion Radiotherapy for Locally Advanced Cervical Adenocarcinoma
Conditions: Cervical Adenocarcinoma · Cervical Adenosquamous Carcinoma·Matched via name phrase
- NCT06783153·NOT YET RECRUITING·Efficacy and Safety of Adjunctive Use of Rifaximin In Preventing Radiotherapy-induced Diarrhea in Cancer Patients
Conditions: Radiotherapy Induced Diarrhea · Acute Radiation Enteritis · Prostate Cancer · Cervical Adenocarcinoma·Matched via name phrase
- NCT07454642·RECRUITING·AVA6103 in Subjects With Locally Advanced or Metastatic Selected Solid Tumors
Conditions: Vulvar Adenocarcinoma · PDAC - Pancreatic Ductal Adenocarcinoma · Gastric Adenocarcinoma · GEJ Adenocarcinoma·Matched via name phrase
- NCT06730347·RECRUITING·A Study of Lorigerlimab in Participants With Advanced Solid Tumors
Conditions: Platinum-resistant Ovarian Cancer · Platinum-Resistant Fallopian Tube Carcinoma · Platinum-Resistant Primary Peritoneal Carcinoma · Clear Cell Adenocarcinoma of Ovary·Matched via name phrase
- NCT06654011·RECRUITING·IN10018 With Nab-Paclitaxel and Cadonilimab for Metastatic or Recurrent Gastric-Type Cervical Adenocarcinoma: Phase 2 Trial
Conditions: Cervical Adenocarcinoma · Gastric-type Endocervical Adenocarcinoma·Matched via name phrase
- NCT07276360·RECRUITING·Hypofractionated Radiotherapy for the Treatment of Locally Advanced Cervical Cancer in Uganda
Conditions: Cervical Cancer · Cervix Cancer · Cervical Adenocarcinoma · Cervical Small Cell Carcinoma·Matched via name phrase
- NCT07141186·NOT YET RECRUITING·QL1706 in Patients With Recurrent and Metastatic Cervical Cancer Resistant to Prior PD-1/PD-L1 Antibody Therapy
Conditions: Cervical Cancer · Cervical Cancer Metastatic · Cervical Cancer Recurrent · Cervical Adenocarcinoma·Matched via name phrase
- NCT06543576·RECRUITING·External Beam Radiation Therapy and Brachytherapy With Chemotherapy and Immunotherapy for the Treatment of Stage IVB Cervical Cancer
Conditions: Cervical Adenocarcinoma · Cervical Adenosquamous Carcinoma · Cervical Squamous Cell Carcinoma · Stage IVB Cervical Cancer American Joint Committee on Cancer (AJCC) v8·Matched via name phrase
Broader category: adenocarcinoma
3,633
Interventional trials for the parent category, exclusive of NCT IDs already counted above. Eligibility for this subtype is not guaranteed.
Worth raising with a clinician. How we count trials.
Recruiting under the broader category
- NCT07125248·RECRUITING·Outcomes of a Single Chest Drain vs Two Drains
Conditions: Pleura; Effusion · Esophageal Adenocarcinoma · Esophageal Anastomotic Leak·Matched via name phrase
- NCT06967662·ENROLLING BY INVITATION·Selective Plasma Adsorption of Extracellular DNA in Prevention of Intraoperative Metastasis in Pancreatic Cancer (Pilot Study)
Conditions: Pancreatic Ductal Adenocarcinoma (PDAC)·Matched via name phrase
- NCT06655142·NOT YET RECRUITING·OSCAR II STUDY - The ONCObind CTC Removal Study
Conditions: Pancreatic Ductal Adenocarcinoma (mPDAC) · Metastatic Colorectal Carcinoma (mCRC)·Matched via name phrase
- NCT06067269·RECRUITING·Hormone Therapy (Apalutamide) and Image-guided Stereotactic Body Radiation Therapy for the Treatment of Patients With Prostate Cancer, HEATWAVE Trial
Conditions: Prostate Adenocarcinoma · Stage II Prostate Cancer AJCC v8 · Stage IIIA Prostate Cancer AJCC v8 · Stage IIIB Prostate Cancer AJCC v8·Matched via name phrase
- NCT06982222·NOT YET RECRUITING·Testing the Safety of the Anti-cancer Drug, Sn-117m-DTPA, for Advanced Cancers That Have Spread to Bones
Conditions: Anatomic Stage IV Breast Cancer AJCC v8 · Metastatic Breast Carcinoma · Metastatic Lung Non-Small Cell Carcinoma · Metastatic Malignant Neoplasm in the Bone·Matched via name phrase
- NCT06079346·RECRUITING·A Study of OT-101 With mFOLFIRINOX in Patients With Advanced and Unresectable or Metastatic Pancreatic Cancer
Conditions: Pancreatic Ductal Adenocarcinoma·Matched via name phrase
- NCT07468903·RECRUITING·Focal Radiation Therapy (HDR-Brachytherapy) for the Treatment of Prostate Cancer
Conditions: Prostate Adenocarcinoma · Stage I Prostate Cancer American Joint Committee on Cancer (AJCC) v8 · Stage II Prostate Cancer AJCC v8·Matched via name phrase
- NCT06199895·RECRUITING·Clinical Efficacy and Safety of Paclitaxel Polymeric Micelles for Injection in the Treatment of Patients With Taxans-resistant Pancreatic Adenocarcinoma, Cholangiocarcinoma, Lung Cancer, Gastric Cancer, Esophageal Carcinoma, or Breast Cancer
Conditions: Pancreatic Adenocarcinoma · Cholangiocarcinoma · Lung Cancer · Stomach Cancer·Matched via name phrase
- NCT06361030·NOT YET RECRUITING·Surufatinib Combined With Gemcitabine Plus Nab-paclitaxel in Locally Advanced Pancreatic Cancer
Conditions: Pancreatic Cancer · Pancreatic Cancer Non-resectable · Pancreatic Ductal Adenocarcinoma, PDAC·Matched via name phrase
- NCT04146298·RECRUITING·Mutant KRAS G12V-specific TCR Transduced T Cell Therapy for Advanced Pancreatic Cancer
Conditions: Pancreatic Cancer · Pancreatic Neoplasms · Pancreatic Ductal Adenocarcinoma · Advanced Cancer·Matched via name phrase
- NCT06161532·RECRUITING·Sacituzumab Govitecan With or Without Atezolizumab Immunotherapy in Rare Genitourinary Tumors (SMART) Such as High Grade Neuroendocrine Carcinomas, Adenocarcinoma, and Squamous Cell Bladder/Urinary Tract Cancer, Renal Medullary Carcinoma and Penile C...
Conditions: Small Cell Carcinoma of the Bladder · Small Cell Carcinoma of the Urinary Tract · Squamous Cell Carcinoma of the Bladder · Squamous Cell Carcinoma of the Urinary Tract·Matched via name phrase
- NCT07103668·RECRUITING·A Phase III Randomized Study in CLDN18.2-positive Unresectable Locally Advanced Gastric Cancer Patients
Conditions: Gastric Adenocarcinoma·Matched via name phrase
- NCT06794073·RECRUITING·Efficacy and Safety of Multimodal Ablation Combined With PD-1 Monoclonal Antibody, Lenvatinib and TACE in the Treatment of Unresectable Primary Hepatocellular Carcinoma: A Single-Arm, Single-Center Clinical Study
Conditions: Carcinoma, Hepatocellular · Neoplasms, Glandular and Epithelial · Adenocarcinoma · Digestive System Neoplasms·Matched via name phrase
- NCT06861088·RECRUITING·The Effect of Kinisoquin™ on Thromboembolic Events in Patients With Metastatic or Locally Advanced Pancreatic Cancer
Conditions: Venous Thromboembolism · Metastatic Pancreatic Cancer · Locally Advanced Pancreatic Adenocarcinoma·Matched via name phrase
- NCT06454383·RECRUITING·Gemcitabine and Leflunomide in Patients With Advanced Unresectable Pancreatic Cancer
Conditions: Advanced Pancreatic Adenocarcinoma · Stage III Pancreatic Cancer AJCC v8 · Stage IV Pancreatic Cancer AJCC v8 · Unresectable Pancreatic Ductal Adenocarcinoma·Matched via name phrase
Observational and natural-history studies
9 observational studies match this condition. These do not test a treatment and are not counted in the interventional-trial headline, but they are genuine research: natural-history work often defines the endpoints needed for a future rare-disease trial, and families may be able to enroll.
Recruiting or not-yet-recruiting
- NCT05046080·RECRUITING·Clinicopathologic and Ancillary Testing of Primary Clear Cell Carcinoma of the Cervix
Conditions: Human Papillomavirus-Independent Cervical Adenocarcinoma, Clear Cell-Type·Matched via name phrase
Where to find support
We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:
India — NPRD
Last verified 2026-07-26This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.
Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.
How we counted this
Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored on the overview but are not added to the query string.
"Adenocarcinoma of the cervix uteri" OR "Adenocarcinoma of cervix uteri" OR "Cervical adenocarcinoma" OR "adenocarcinoma - cervix" OR "adenocarcinoma of cervix" OR "adenocarcinoma of the cervix" OR "adenocarcinoma of the uterine cervix" OR "adenocarcinoma of uterine cervix" OR "cervix adenocarcinoma" OR "cervix uteri adenocarcinoma" OR "uterine cervix adenocarcinoma"
ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):
"Adenocarcinoma of the cervix uteri" OR "Adenocarcinoma of cervix uteri" OR "Cervical adenocarcinoma" OR "adenocarcinoma - cervix" OR "adenocarcinoma of cervix" OR "adenocarcinoma of the cervix" OR "adenocarcinoma of the uterine cervix" OR "adenocarcinoma of uterine cervix" OR "cervix adenocarcinoma" OR "cervix uteri adenocarcinoma" OR "uterine cervix adenocarcinoma"
Interventional trials matched via: phrase (mesh = registered under a MeSH descriptor no name phrase would catch; recall-expansion = gene / selected parent terms used only for trials).
Study-type breakdown: 59 interventional · 9 observational · 0 expanded access. Only interventional studies enter the trial headline.
Parent-category trials query:
"adenocarcinoma"
Query health: ok — strategies attempted: phrase; with hits: phrase
Run this search on ClinicalTrials.gov
Confidence reasoning
- Preferred label is multi-word and distinctive
- No synonyms dropped by stoplist
- No label/synonym collisions with other diseases in this corpus
Ingested 2026-07-27T09:38:17.738Z
