ORPHA:213600
Adenosarcoma of the corpus uteri
Publications
46
36.4th percentile
Trials
0
Interventional, condition-specific
Researchers
239
Distinct authors in sample
Gene link
—
Readiness
2/6
Stages with a signal
Clinical definition (Orphanet)
A rare subtype of mixed epithelial-mesenchymal tumor, often presenting as a large, exophytic polypoid lesion, which may extend through the cervix, composed of benign or atypical epithelium and low-grade malignant stroma. It usually presents with dysfunctional bleeding or vaginal discharge and less often abdominal pain. Association with long-term unopposed estrogen therapy, tamoxifen therapy and a history of pelvic radiation has been reported.
Cross-references
Joined from Mondo / Orphanet. MeSH labels may enter searches; UMLS / OMIM / NCIT are stored for reference.
- MONDO:0002878
- MeSH:C538232
- UMLS:C1336917
- NCIT:C6336
Additional Mondo synonyms (13)
adenosarcoma of body of uterus · adenosarcoma of the body of uterus · adenosarcoma of the corpus uteri · adenosarcoma of the uterine body · adenosarcoma of the uterine corpus · adenosarcoma of uterine body · adenosarcoma of uterine corpus · body of uterus adenosarcoma · uterine body adenosarcoma · uterine corpus Mullerian adenosarcoma · uterine corpus Müllerian adenosarcoma · uterine corpus adenosarcoma · uterine corpus mullerian adenosarcoma
Research stages
Trial readiness signals
Where this condition sits on an open-data research pipeline — not how close a treatment is, and not medical advice. Empty stages often mean “not in these databases under this Mondo ID,” not “impossible.”
2/6 stages with a signal
No specific-condition interventional trial, but broader-category trials exist — discuss eligibility with a clinician.
- Gene identifiedNot found
No GenCC disease–gene assertion in this build
- LiteraturePresent
46 matched papers (19 in last 10 years) Source
- Phenotype characterisedNot checked
Not yet enriched from Monarch / HPO
- Animal modelNot checked
Not yet enriched from Monarch / Alliance
- Orphan designationNot checked
FDA/EMA orphan-drug designation not enriched yet
- Interventional trialPartial
None under the specific name; 3 for broader category adenosarcoma
Biology
Genes and phenotypes
Gene–disease validity from GenCC, plus phenotypes and animal models joined from Monarch Initiative via Mondo ID — not a clinical diagnosis aid.
Do we know what causes it?
Not yet — the cause hasn't been pinned down in GenCC.
No strong gene–disease assertion joined for this Orphanet entity.
Phenotypes (Monarch / HPO)
Not enriched in this build — Monarch phenotype joins were not run for this record.
Animal models (Monarch / Alliance)
Not enriched in this build.
Literature
Is anyone studying this?
46
46 papers have ever been published on this condition (under this name). For scale, breast cancer has over 700,000. Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=5449) is 41.
46 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 41 (publications denominator n=5449).
19 in the last 10 years · high confidence · 36.4th percentile (publications denominator)
Phrase hits: 37 · MeSH hits: 9
Who's working on it?
239
Distinct author names in 46 sampled papers — named people below.
Who's working on it?
No interventional trial matched this name; these authors publish on it in the sampled literature — a practical starting point for contact.
- 01Liu Q2 papers · 2024
Cheeloo College of Medicine, Shandong University, Jinan, China.
Papers in Europe PMC - 02Young RH2 papers · 2005Papers in Europe PMC
- 03Agrifoglio V1 paper · 2024
Unit of Obstetrics and Gynecology, "Paolo Giaccone" Hospital, Palermo, Italy.
Papers in Europe PMC - 04Aguiar Losada B1 paper · 2024
Department of Surgical Pathology in the University Hospital Donostia in San Sebastian, Basque Country, Spain.
Papers in Europe PMC - 05Aizawa S1 paper · 2001Papers in Europe PMC
- 06Alsannan B1 paper · 2024
Department of Obstetrics and Gynecology, College of Medicine, Kuwait University, Safat, Kuwait.
Papers in Europe PMC - 07Álvarez-Álvarez R1 paper · 2026
Medical Oncology Department, Gregorio Marañón University Hospital, 28007 Madrid, Spain;
Papers in Europe PMC - 08Arend RC1 paper · 2009Papers in Europe PMC
- 09Asencio-Pascual J1 paper · 2026
Hepatobiliary Surgery and Liver Transplant Unit, Gregorio Marañón University Hospital, 28007 Madrid, Spain;
Papers in Europe PMC - 10Austria T1 paper · 2018
Department of Pathology, USC/Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA.
Papers in Europe PMC
Clinical research
Is a treatment being tested?
0
interventional trials for this specific condition
No interventional trial testing a treatment matched this specific condition name on ClinicalTrials.gov (observational studies and pan-disease registries are listed separately when present). 3 trials are registered for adenosarcoma, the broader category — shown separately because they may or may not enrol this specific subtype.
Data as of 27 July 2026
No matched interventional trials. This is true for 73% of diseases in the trials denominator (5114 of 7003). Here are the researchers publishing on it.
high confidence · 36.5th percentile (trials denominator)
Recruiting interventional trials
From the matched ClinicalTrials.gov set
No interventional trial testing a treatment was found for this specific condition name on ClinicalTrials.gov.
3 interventional trials matched adenosarcoma, the broader category — listed below. Those studies are not counted in the condition-specific total.
Broader category: adenosarcoma
3
Interventional trials for the parent category, exclusive of NCT IDs already counted above. Eligibility for this subtype is not guaranteed.
Worth raising with a clinician. How we count trials.
Recruiting under the broader category
- NCT07467772·RECRUITING·Ph 2 Elacestrant in ER Positive Uterine Sarcomas
Conditions: Uterine Sarcoma · Uterine Leiomyosarcoma · Endometrial Stromal Sarcoma · ESS·Matched via name phrase
Where to find support
We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:
India — NPRD
Last verified 2026-07-26This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.
Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.
How we counted this
Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored on the overview but are not added to the query string.
"Adenosarcoma of the corpus uteri" OR "Adenosarcoma of corpus uteri" OR "adenosarcoma of body of uterus" OR "adenosarcoma of the body of the uterus" OR "adenosarcoma of the body of uterus" OR "adenosarcoma of the uterine body" OR "adenosarcoma of uterine body" OR "adenosarcoma of the uterine corpus" OR "adenosarcoma of uterine corpus" OR "body of uterus adenosarcoma" OR "body of the uterus adenosarcoma" OR "uterine body adenosarcoma" OR "uterine corpus Mullerian adenosarcoma" OR "uterine corpus Müllerian adenosarcoma" OR "uterine corpus adenosarcoma"
MeSH descriptor terms unioned into the query: Adenosarcoma of the uterus
ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):
"Adenosarcoma of the corpus uteri" OR "Adenosarcoma of corpus uteri" OR "adenosarcoma of body of uterus" OR "adenosarcoma of the body of the uterus" OR "adenosarcoma of the body of uterus" OR "adenosarcoma of the uterine body" OR "adenosarcoma of uterine body" OR "adenosarcoma of the uterine corpus" OR "adenosarcoma of uterine corpus" OR "body of uterus adenosarcoma" OR "body of the uterus adenosarcoma" OR "uterine body adenosarcoma" OR "uterine corpus Mullerian adenosarcoma" OR "uterine corpus Müllerian adenosarcoma" OR "uterine corpus adenosarcoma" OR "Adenosarcoma of the uterus"
Study-type breakdown: 0 interventional · 0 observational · 0 expanded access. Only interventional studies enter the trial headline.
Parent-category trials query:
"adenosarcoma"
Query health: ok — strategies attempted: phrase, mesh; with hits: phrase, mesh
Run this search on ClinicalTrials.gov
Confidence reasoning
- Preferred label is multi-word and distinctive
- No synonyms dropped by stoplist
- No label/synonym collisions with other diseases in this corpus
Ingested 2026-07-27T09:34:32.569Z