ORPHA:213504
Adenocarcinoma of ovary
Also known as: Ovarian adenocarcinoma
Publications
7,740
96.9th percentile
Trials
24
Interventional, condition-specific
Researchers
1,136
Distinct authors in sample
Gene link
—
Readiness
2/6
Stages with a signal
How rare: 1-9 / 100 000 — about one to nine people per hundred thousand.
Cross-references
Joined from Mondo / Orphanet. MeSH labels may enter searches; UMLS / OMIM / NCIT are stored for reference.
- MONDO:0002752
- UMLS:C0948216
- NCIT:C7700
Additional Mondo synonyms (4)
adenocarcinoma of ovary · adenocarcinoma of the ovary · ovarian adenocarcinoma · ovary adenocarcinoma
Research stages
Trial readiness signals
Where this condition sits on an open-data research pipeline — not how close a treatment is, and not medical advice. Empty stages often mean “not in these databases under this Mondo ID,” not “impossible.”
2/6 stages with a signal
An interventional trial matched this condition name on ClinicalTrials.gov — see trials below.
- Gene identifiedNot found
No GenCC disease–gene assertion in this build
- LiteraturePresent
7,740 matched papers (3,760 in last 10 years) Source
- Phenotype characterisedNot checked
Not yet enriched from Monarch / HPO
- Animal modelNot checked
Not yet enriched from Monarch / Alliance
- Orphan designationNot checked
FDA/EMA orphan-drug designation not enriched yet
- Interventional trialPresent
24 matched on ClinicalTrials.gov (7 recruiting in sample)
Biology
Genes and phenotypes
Gene–disease validity from GenCC, plus phenotypes and animal models joined from Monarch Initiative via Mondo ID — not a clinical diagnosis aid.
Do we know what causes it?
Not yet — the cause hasn't been pinned down in GenCC.
No strong gene–disease assertion joined for this Orphanet entity.
Phenotypes (Monarch / HPO)
Not enriched in this build — Monarch phenotype joins were not run for this record.
Animal models (Monarch / Alliance)
Not enriched in this build.
Literature
Is anyone studying this?
7,740
7,740 papers — among the better-studied rare conditions, though still a fraction of common-disease literature (breast cancer: over 700,000). Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=5449) is 41.
7,740 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 41 (publications denominator n=5449).
3,760 in the last 10 years · high confidence · 96.9th percentile (publications denominator)
Phrase hits: 7,740 · MeSH hits: 0
Who's working on it?
1,136
Distinct author names in 200 sampled papers — named people below.
Who's working on it?
People publishing on this condition (sampled Europe PMC records). Affiliation is the most recent found in that sample.
- 01Tuncer MC8 papers · 2025
Department of Anatomy, Faculty of Medicine, Dicle University, Diyarbakir 21280, Turkey.
Papers in Europe PMC - 02Özdemir İ7 papers · 2025
Department of Histology and Embryology, Faculty of Medicine, Kahramanmaraş Sütçü İmam University, Kahramanmaraş 46100, Turkey.
Papers in Europe PMC - 03Öztürk Ş5 papers · 2025
Vocational School of Health Services, Çanakkale Onsekiz Mart University, Çanakkale 17100, Turkey.
Papers in Europe PMC - 04Solár P5 papers · 2026
Department of Medical Biology, Faculty of Medicine, Pavol Jozef Šafárik University in Košice, SK-04154, Košice, Slovak Republic. Electronic address: peter.solar@upjs.sk.
Papers in Europe PMC - 05Solárová Z5 papers · 2026
Department of Pharmacology, Faculty of Medicine, Pavol Jozef Šafárik University in Košice, SK-04154, Košice, Slovak Republic.
Papers in Europe PMC - 06Wang Y5 papers · 2026
Department of Medical Oncology, Affiliated Dongyang Hospital of Wenzhou Medical University Dongyang, Zhejiang, China.
Papers in Europe PMC - 07Bhide M4 papers · 2026
Institute of Neuroimmunology, Slovak Academy of Sciences, Dubravska cesta 9, SK-841 04, Bratislava, Slovak Republic; Laboratory of Biomedical Microbiology and Immunology, University of Veterinary Medicine and Pharmacy in Košice, SK-04154, Košice, Slovak Republic.
Papers in Europe PMC - 08Harvanik P4 papers · 2026
Department of Medical Biology, Faculty of Medicine, Pavol Jozef Šafárik University in Košice, SK-04154, Košice, Slovak Republic.
Papers in Europe PMC - 09Liu Y4 papers · 2025
Hubei Provincial Key Laboratory for Chinese Medicine Resources and Chinese Medicine Chemistry, School of Pharmacy, Hubei University of Chinese Medicine, Wuhan, China.
Papers in Europe PMC - 10
Clinical research
Is a treatment being tested?
24
interventional trials for this specific condition
24 interventional trials matched this specific condition name; 7 currently recruiting in our sample. 3,668 trials are registered for adenocarcinoma, the broader category — shown separately because they may or may not enrol this specific subtype.
Data as of 27 July 2026
24 interventional trials — more than 73% of diseases in the trials denominator have none at all (5114 of 7003; this disease is at the 95th percentile).
high confidence · 95th percentile (trials denominator)
Recruiting interventional trials
From the matched ClinicalTrials.gov set
24 interventional trials matched after quoted-phrase search and title/condition post-filter.
- NCT05601700·RECRUITING·Letrozole for Estrogen/Progesterone Receptor Positive Low-grade Serous Epithelial Ovarian Cancer (LEPRE Trial)
Conditions: Carcinoma, Ovarian Epithelial · Low Grade Serous Adenocarcinoma of Ovary·Matched via name phrase
- NCT06730347·RECRUITING·A Study of Lorigerlimab in Participants With Advanced Solid Tumors
Conditions: Platinum-resistant Ovarian Cancer · Platinum-Resistant Fallopian Tube Carcinoma · Platinum-Resistant Primary Peritoneal Carcinoma · Clear Cell Adenocarcinoma of Ovary·Matched via name phrase
- NCT07705035·RECRUITING·DBC-664 in Adult Patients With Solid Tumors
Conditions: Malignant Germ Cell Tumor · Lung Adenocarcinoma · Gastric/Esophageal/Gastroesophageal Junction (GEJ) Adenocarcinoma · Urothelial Carcinoma·Matched via name phrase
- NCT05500391·RECRUITING·Assessment of Compliance With Monitoring Conducted by a Physician in Person or by a Nurse in Remote Monitoring
Conditions: Stage I Testicular Seminoma · Stage I Testicular Nonseminomatous Germ Cell Tumor · Gastrointestinal Stromal Tumors · Ovarian Germ Cell Tumor·Matched via name phrase
- NCT05902988·RECRUITING·A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer
Conditions: Advanced Solid Tumor · High Grade Serous Adenocarcinoma of Ovary · Squamous Non-small-cell Lung Cancer · Triple Negative Breast Cancer·Matched via name phrase
- NCT07429487·NOT YET RECRUITING·Assessment of Adherence to Remotely Monitored Physical Activity Tracked on a Smartwatch, and Its Impact on Reducing Fatigue 3 Months After Adjuvant Chemotherapy for Cancer
Conditions: Breast Cancer · Colorectal Cancer · Ovarian Adenocarcinoma · Pancreatic Cancer·Matched via name phrase
- NCT06063070·NOT YET RECRUITING·First-line Maintenance Treatment With Fluzoparib Plus Bevacizumab in Advanced BRCA Wild Type Ovarian Cancer
Conditions: Ovarian Cancer · High Grade Serous Adenocarcinoma of Ovary · High Grade Endometrioid Ovarian Cancer · Primary Peritoneal Cancer·Matched via name phrase
Broader category: adenocarcinoma
3,668
Interventional trials for the parent category, exclusive of NCT IDs already counted above. Eligibility for this subtype is not guaranteed.
Worth raising with a clinician. How we count trials.
Recruiting under the broader category
- NCT07125248·RECRUITING·Outcomes of a Single Chest Drain vs Two Drains
Conditions: Pleura; Effusion · Esophageal Adenocarcinoma · Esophageal Anastomotic Leak·Matched via name phrase
- NCT06967662·ENROLLING BY INVITATION·Selective Plasma Adsorption of Extracellular DNA in Prevention of Intraoperative Metastasis in Pancreatic Cancer (Pilot Study)
Conditions: Pancreatic Ductal Adenocarcinoma (PDAC)·Matched via name phrase
- NCT06655142·NOT YET RECRUITING·OSCAR II STUDY - The ONCObind CTC Removal Study
Conditions: Pancreatic Ductal Adenocarcinoma (mPDAC) · Metastatic Colorectal Carcinoma (mCRC)·Matched via name phrase
- NCT06067269·RECRUITING·Hormone Therapy (Apalutamide) and Image-guided Stereotactic Body Radiation Therapy for the Treatment of Patients With Prostate Cancer, HEATWAVE Trial
Conditions: Prostate Adenocarcinoma · Stage II Prostate Cancer AJCC v8 · Stage IIIA Prostate Cancer AJCC v8 · Stage IIIB Prostate Cancer AJCC v8·Matched via name phrase
- NCT06982222·NOT YET RECRUITING·Testing the Safety of the Anti-cancer Drug, Sn-117m-DTPA, for Advanced Cancers That Have Spread to Bones
Conditions: Anatomic Stage IV Breast Cancer AJCC v8 · Metastatic Breast Carcinoma · Metastatic Lung Non-Small Cell Carcinoma · Metastatic Malignant Neoplasm in the Bone·Matched via name phrase
- NCT06079346·RECRUITING·A Study of OT-101 With mFOLFIRINOX in Patients With Advanced and Unresectable or Metastatic Pancreatic Cancer
Conditions: Pancreatic Ductal Adenocarcinoma·Matched via name phrase
- NCT07468903·RECRUITING·Focal Radiation Therapy (HDR-Brachytherapy) for the Treatment of Prostate Cancer
Conditions: Prostate Adenocarcinoma · Stage I Prostate Cancer American Joint Committee on Cancer (AJCC) v8 · Stage II Prostate Cancer AJCC v8·Matched via name phrase
- NCT06199895·RECRUITING·Clinical Efficacy and Safety of Paclitaxel Polymeric Micelles for Injection in the Treatment of Patients With Taxans-resistant Pancreatic Adenocarcinoma, Cholangiocarcinoma, Lung Cancer, Gastric Cancer, Esophageal Carcinoma, or Breast Cancer
Conditions: Pancreatic Adenocarcinoma · Cholangiocarcinoma · Lung Cancer · Stomach Cancer·Matched via name phrase
- NCT06361030·NOT YET RECRUITING·Surufatinib Combined With Gemcitabine Plus Nab-paclitaxel in Locally Advanced Pancreatic Cancer
Conditions: Pancreatic Cancer · Pancreatic Cancer Non-resectable · Pancreatic Ductal Adenocarcinoma, PDAC·Matched via name phrase
- NCT04146298·RECRUITING·Mutant KRAS G12V-specific TCR Transduced T Cell Therapy for Advanced Pancreatic Cancer
Conditions: Pancreatic Cancer · Pancreatic Neoplasms · Pancreatic Ductal Adenocarcinoma · Advanced Cancer·Matched via name phrase
- NCT06161532·RECRUITING·Sacituzumab Govitecan With or Without Atezolizumab Immunotherapy in Rare Genitourinary Tumors (SMART) Such as High Grade Neuroendocrine Carcinomas, Adenocarcinoma, and Squamous Cell Bladder/Urinary Tract Cancer, Renal Medullary Carcinoma and Penile C...
Conditions: Small Cell Carcinoma of the Bladder · Small Cell Carcinoma of the Urinary Tract · Squamous Cell Carcinoma of the Bladder · Squamous Cell Carcinoma of the Urinary Tract·Matched via name phrase
- NCT07103668·RECRUITING·A Phase III Randomized Study in CLDN18.2-positive Unresectable Locally Advanced Gastric Cancer Patients
Conditions: Gastric Adenocarcinoma·Matched via name phrase
- NCT06794073·RECRUITING·Efficacy and Safety of Multimodal Ablation Combined With PD-1 Monoclonal Antibody, Lenvatinib and TACE in the Treatment of Unresectable Primary Hepatocellular Carcinoma: A Single-Arm, Single-Center Clinical Study
Conditions: Carcinoma, Hepatocellular · Neoplasms, Glandular and Epithelial · Adenocarcinoma · Digestive System Neoplasms·Matched via name phrase
- NCT06861088·RECRUITING·The Effect of Kinisoquin™ on Thromboembolic Events in Patients With Metastatic or Locally Advanced Pancreatic Cancer
Conditions: Venous Thromboembolism · Metastatic Pancreatic Cancer · Locally Advanced Pancreatic Adenocarcinoma·Matched via name phrase
- NCT06454383·RECRUITING·Gemcitabine and Leflunomide in Patients With Advanced Unresectable Pancreatic Cancer
Conditions: Advanced Pancreatic Adenocarcinoma · Stage III Pancreatic Cancer AJCC v8 · Stage IV Pancreatic Cancer AJCC v8 · Unresectable Pancreatic Ductal Adenocarcinoma·Matched via name phrase
Observational and natural-history studies
7 observational studies match this condition. These do not test a treatment and are not counted in the interventional-trial headline, but they are genuine research: natural-history work often defines the endpoints needed for a future rare-disease trial, and families may be able to enroll.
Recruiting or not-yet-recruiting
- NCT06883487·RECRUITING·Exploratory Study on HER2 Detection Method and Positive Threshold for High-grade Serous Adenocarcinoma of the Ovary
Conditions: Exploring HER2 Positive Diagnostic Criteria in High-grade Serous Ovarian Cancer · Observing the Effectiveness of Targeted HER2 ADC Drugs·Matched via name phrase
- NCT07675967·RECRUITING·Clonal Hematopoiesis Chemotherapy and Radiation Effects Study
Conditions: Lung Cancer (Diagnosis) · Osteochondroma · Spitz Nevus · Solid Cancers·Matched via name phrase
- NCT07100288·RECRUITING·Anatomopathological Analysis of the Infundibulopelvic Ligament in Patients With Ovarian Cancer
Conditions: Ovarian Cancer · Ovarian Cancer (OvCa) · Ovarian Adenocarcinoma·Matched via name phrase
- NCT07168083·NOT YET RECRUITING·Efficacy and Safety of Sacituzumab in Patients With OCCC After Immunotherapy Progression
Conditions: Ovarian Cancer · Antibody-drug Conjugates · Clear Cell Adenocarcinoma of Ovary·Matched via name phrase
Where to find support
We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:
India — NPRD
Last verified 2026-07-26This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.
Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.
How we counted this
Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored on the overview but are not added to the query string.
"Adenocarcinoma of ovary" OR "Adenocarcinoma of the ovary" OR "Ovarian adenocarcinoma" OR "ovary adenocarcinoma"
ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):
"Adenocarcinoma of ovary" OR "Adenocarcinoma of the ovary" OR "Ovarian adenocarcinoma" OR "ovary adenocarcinoma"
Interventional trials matched via: phrase (mesh = registered under a MeSH descriptor no name phrase would catch; recall-expansion = gene / selected parent terms used only for trials).
Study-type breakdown: 24 interventional · 7 observational · 0 expanded access. Only interventional studies enter the trial headline.
Parent-category trials query:
"adenocarcinoma"
Query health: ok — strategies attempted: phrase; with hits: phrase
Run this search on ClinicalTrials.gov
Confidence reasoning
- Preferred label is multi-word and distinctive
- No synonyms dropped by stoplist
- No label/synonym collisions with other diseases in this corpus
Ingested 2026-07-27T09:33:12.576Z
