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ORPHA:206594

Subacute inflammatory demyelinating polyneuropathy

medium confidenceDisorder

Also known as: Subacute inflammatory demyelinating polyradiculoneuropathy

Publications

334

76.5th percentile

Trials

0

Interventional, condition-specific

Researchers

1,145

Distinct authors in sample

Gene link

—

Readiness

2/6

Stages with a signal

Clinical definition (Orphanet)

A rare neuroinflammatory disease characterized by muscular weakness with impaired sensation, absent or diminished tendon reflexes and elevated cerebrospinal fluid (CSF) protein content. Subacute inflammatory demyelinating polyneuropathy (SIDP) is an intermediate form between Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyneuropathy (CIDP).

How rare: How common this is has not been clearly measured.

Orphanet entry

Cross-references

Joined from Mondo / Orphanet. MeSH labels may enter searches; UMLS / OMIM / NCIT are stored for reference.

Additional Mondo synonyms (2)

SIDP · subacute inflammatory demyelinating polyradiculoneuropathy

Research stages

Trial readiness signals

Where this condition sits on an open-data research pipeline — not how close a treatment is, and not medical advice. Empty stages often mean “not in these databases under this Mondo ID,” not “impossible.”

2/6 stages with a signal

No specific-condition interventional trial, but broader-category trials exist — discuss eligibility with a clinician.

  1. Gene identifiedNot found

    No GenCC disease–gene assertion in this build

  2. LiteraturePresent

    334 matched papers (176 in last 10 years) Source

  3. Phenotype characterisedNot checked

    Not yet enriched from Monarch / HPO

  4. Animal modelNot checked

    Not yet enriched from Monarch / Alliance

  5. Orphan designationNot checked

    FDA/EMA orphan-drug designation not enriched yet

  6. Interventional trialPartial

    None under the specific name; 54 for broader category demyelinating polyneuropathy

Biology

Genes and phenotypes

Gene–disease validity from GenCC, plus phenotypes and animal models joined from Monarch Initiative via Mondo ID — not a clinical diagnosis aid.

Do we know what causes it?

Not yet — the cause hasn't been pinned down in GenCC.

No strong gene–disease assertion joined for this Orphanet entity.

Phenotypes (Monarch / HPO)

Not enriched in this build — Monarch phenotype joins were not run for this record.

Animal models (Monarch / Alliance)

Not enriched in this build.

Literature

Is anyone studying this?

334

334 papers have ever been published on this condition (under this name). For scale, breast cancer has over 700,000. Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=5449) is 41.

334 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 41 (publications denominator n=5449).

176 in the last 10 years · medium confidence · 76.5th percentile (publications denominator)

Phrase hits: 334 · MeSH hits: 0

Open Europe PMC search

Who's working on it?

1,145

Distinct author names in 200 sampled papers — named people below.

Who's working on it?

No interventional trial matched this name; these authors publish on it in the sampled literature — a practical starting point for contact.

  1. 01
    SANDROCK ALFRED6 papers · 2012
    Papers in Europe PMC
  2. 02
    Kim YH4 papers · 2023

    Biomedical Omics Group, Korea Basic Science Institute, Cheongju, Chungbuk, 28119, Republic of Korea.

    Papers in Europe PMC
  3. 03
    Koszewicz M4 papers · 2026

    Department of Neurology, Wroclaw Medical University, Borowska 213 Str., 50-556 Wroclaw, Poland.

    Papers in Europe PMC
  4. 04
    Li Y4 papers · 2024

    Department of Physiology, School of Life Science, China Medical University, Shenyang, 110122, People's Republic of China.

    Papers in Europe PMC
  5. 05
    Sharma S4 papers · 2022

    Department of Neurology, Indira Gandhi Medical College and Hospital, Shimla, Himachal Pradesh, India.

    Papers in Europe PMC
  6. 06
    Zhang G4 papers · 2026

    Department of Neurology, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.

    Papers in Europe PMC
  7. 07
    Choi BO3 papers · 2022

    Department of Neurology, Sungkyunkwan University School of Medicine, Seoul, 06351, Republic of Korea.

    Papers in Europe PMC
  8. 08
    Dziadkowiak E3 papers · 2026

    Department of Neurology, Wroclaw Medical University, Borowska 213 Str., 50-556 Wroclaw, Poland.

    Papers in Europe PMC
  9. 09
    Gao T3 papers · 2026

    Department of Neurology, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.

    Papers in Europe PMC
  10. 10
    Jo YR3 papers · 2023

    Peripheral Neuropathy Research Center (PNRC), Dong-A University College of Medicine, Busan, 49201, Republic of Korea.

    Papers in Europe PMC

Clinical research

Is a treatment being tested?

0

interventional trials for this specific condition

No interventional trial testing a treatment matched this specific condition name on ClinicalTrials.gov (observational studies and pan-disease registries are listed separately when present). 54 trials are registered for demyelinating polyneuropathy, the broader category — shown separately because they may or may not enrol this specific subtype.

Data as of 27 July 2026

No matched interventional trials. This is true for 73% of diseases in the trials denominator (5114 of 7003). Here are the researchers publishing on it.

medium confidence · 36.5th percentile (trials denominator)

Recruiting interventional trials

From the matched ClinicalTrials.gov set

No interventional trial testing a treatment was found for this specific condition name on ClinicalTrials.gov.

54 interventional trials matched demyelinating polyneuropathy, the broader category — listed below. Those studies are not counted in the condition-specific total.

Broader category: demyelinating polyneuropathy

54

Interventional trials for the parent category, exclusive of NCT IDs already counted above. Eligibility for this subtype is not guaranteed.

Worth raising with a clinician. How we count trials.

Recruiting under the broader category

Where to find support

We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:

India — NPRD

Last verified 2026-07-26

This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.

Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.

How we counted this

Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored on the overview but are not added to the query string.

"Subacute inflammatory demyelinating polyneuropathy" OR "Subacute inflammatory demyelinating polyradiculoneuropathy"

Run this search on Europe PMC

ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):

"Subacute inflammatory demyelinating polyneuropathy" OR "Subacute inflammatory demyelinating polyradiculoneuropathy"

Study-type breakdown: 0 interventional · 0 observational · 0 expanded access. Only interventional studies enter the trial headline.

Parent-category trials query:

"demyelinating polyneuropathy"

Query health: ok — strategies attempted: phrase; with hits: phrase

Run this search on ClinicalTrials.gov

Synonyms dropped by stoplist: SIDP

Confidence reasoning

  • Preferred label is multi-word and distinctive
  • 1 synonym(s) dropped by stoplist (may under-count)
  • No label/synonym collisions with other diseases in this corpus

Ingested 2026-07-27T09:21:29.511Z