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ORPHA:180242

Malignant tumor of fallopian tubes

high confidenceDisorder

Also known as: Cancer of fallopian tubes · Malignant tubal tumor · Tubal cancer

Publications

4,580

92.3th percentile

Trials

561

Interventional, condition-specific

Researchers

1,433

Distinct authors in sample

Gene link

—

Readiness

3/6

Stages with a signal

How rare: 1-9 / 100 000 — about one to nine people per hundred thousand.

Orphanet entry

Cross-references

Joined from Mondo / Orphanet. MeSH labels may enter searches; UMLS / OMIM / NCIT are stored for reference.

Additional Mondo synonyms (22)

cancer of fallopian tube · cancer of fallopian tubes · fallopian tube cancer · fallopian tube malignant neoplasm · fallopian tube malignant tumor · fallopian tube malignant tumour · malignant fallopian tube neoplasm · malignant fallopian tube tumor · malignant fallopian tube tumour · malignant neoplasm of fallopian tube · malignant neoplasm of the fallopian tube · malignant neoplasm of uterine tube · malignant tubal tumor · malignant tubal tumour · malignant tumor of fallopian tube · malignant tumor of fallopian tubes · malignant tumor of the fallopian tube · malignant tumour of fallopian tubes · malignant tumour of the fallopian tube · neoplasm, fallopian tube, malignant · tubal cancer · tumor, fallopian tube, malignant

Research stages

Trial readiness signals

Where this condition sits on an open-data research pipeline — not how close a treatment is, and not medical advice. Empty stages often mean “not in these databases under this Mondo ID,” not “impossible.”

3/6 stages with a signal

An interventional trial matched this condition name on ClinicalTrials.gov — see trials below.

  1. Gene identifiedNot found

    No GenCC disease–gene assertion in this build

  2. LiteraturePresent

    4,580 matched papers (3,100 in last 10 years) Source

  3. Phenotype characterisedNot found

    No HPO disease–phenotype associations via Monarch for these Mondo IDs

  4. Animal modelNot found

    No Alliance genotype “model of” associations via Monarch for these Mondo IDs

  5. Orphan designationPresent

    3 FDA · 1 EMA designations (2 FDA orphan-indication approvals) — e.g. pelareorep Source

  6. Interventional trialPresent

    561 matched on ClinicalTrials.gov (59 recruiting in sample)

Biology

Genes and phenotypes

Gene–disease validity from GenCC, plus phenotypes and animal models joined from Monarch Initiative via Mondo ID — not a clinical diagnosis aid.

Do we know what causes it?

Not yet — the cause hasn't been pinned down in GenCC.

No strong gene–disease assertion joined for this Orphanet entity.

Phenotypes (Monarch / HPO)

None returned for this Mondo ID. That often means “not linked under this ID,” not “no clinical features.”

Animal models (Monarch / Alliance)

None returned for this Mondo ID. Empty here is not proof that no model organism work exists under another name or gene.

Monarch fetch 2026-07-29

Therapies

Designations, candidates, and chemicals

FDA OOPD and EMA orphan designations, Open Targets clinical candidates, and CTD chemical associations via MyDisease.info. These never change the interventional-trial headline.

Orphan designation (FDA · EMA)

4

Designations · 2 with FDA orphan-indication approval

  • FDA pelareorepFallopian Tube Cancer · 2015-02-24 · Not FDA Approved for Orphan Indication
  • FDA patupiloneFallopian Tube Cancer · 2010-02-02 · Not FDA Approved for Orphan Indication
  • FDA olaparib (Lynparza)Fallopian Tube Cancer · 2018-05-15
  • EMA patupiloneTreatment of fallopian tube cancer · 05/11/2009 · WithdrawnEMA designation

Sources: FDA OOPD · EMA orphan designations

Open Targets candidates

237

Drugs / clinical candidates · MONDO_0002158

CTD chemicals (MyDisease.info)

No CTD chemical associations returned for this Mondo ID.

Literature

Is anyone studying this?

4,580

4,580 papers have been published on this condition. That is a real research literature — still far smaller than common diseases (breast cancer: over 700,000 papers). Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=3967) is 59.

4,580 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 59 (publications denominator n=3967).

3,100 in the last 10 years · high confidence · 92.3th percentile (publications denominator)

Phrase hits: 4,580 · MeSH hits: 0

Open Europe PMC search

Who's working on it?

1,433

Distinct author names in 200 sampled papers — named people below.

Who's working on it?

People publishing on this condition (sampled Europe PMC records). Affiliation is the most recent found in that sample.

  1. 01
    Wang Y10 papers · 2026

    Department of Obstetrics and Gynecology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung City 833, Taiwan.

    Papers in Europe PMC
  2. 02
    Li Y9 papers · 2026

    Department of Assisted Reproductive Centre, The affiliated Zhuzhou hospital Xiangya medical college, Central South University, Zhuzhou, Hunan, China.

    Papers in Europe PMC
  3. 03
    Chen X7 papers · 2026

    Department of Epidemiology and Statistics, School of Public Health, Medical College, Zhejiang University, Hangzhou, Zhejiang, China.

    Papers in Europe PMC
  4. 04
    Chen Y5 papers · 2025

    Department of Gynecological Oncology, Tianjin Medical University Cancer Institute & Hospital, Tianjin, People's Republic of China.

    Papers in Europe PMC
  5. 05
    Liu H5 papers · 2025

    Department of Gynecology, Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing, China.

    Papers in Europe PMC
  6. 06
    Liu Y4 papers · 2026

    Department of Gynecological Oncology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, Beijing 100006, China.

    Papers in Europe PMC
  7. 07
    Ma Y4 papers · 2026

    Department of Pathology, The Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu, China.

    Papers in Europe PMC
  8. 08
    Zhou J4 papers · 2024

    Department of Obstetrics and Gynecology, The Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, China.

    Papers in Europe PMC
  9. 09
    Chan JK3 papers · 2026

    Division of Gynecologic Oncology, Palo Alto Medical Foundation, California Pacific Medical Center, Sutter Health, San Francisco, CA, USA.

    Papers in Europe PMC
  10. 10
    Colombo N3 papers · 2025

    European Institute of Oncology IRCCS Library, Milan, Italy.

    Papers in Europe PMC

Clinical research

Is a treatment being tested?

561

interventional trials for this specific condition

561 interventional trials matched this specific condition name; 59 currently recruiting in our sample.

Data as of 11 September 2026

561 interventional trials — more than 77.2% of diseases in the trials denominator have none at all (5501 of 7126; this disease is at the 99.7th percentile).

high confidence · 99.7th percentile (trials denominator)

Recruiting interventional trials

From the matched ClinicalTrials.gov set

561 interventional trials matched after quoted-phrase search and title/condition post-filter.

Observational and natural-history studies

59 observational studies match this condition. These do not test a treatment and are not counted in the interventional-trial headline, but they are genuine research: natural-history work often defines the endpoints needed for a future rare-disease trial, and families may be able to enroll.

Recruiting or not-yet-recruiting

Open the complete matched search on ClinicalTrials.gov

Other registries (secondary)

Broader net from EU CTIS, ISRCTN, and ICTRP when available — deduped against ClinicalTrials.gov IDs already counted above. Dual-model LLM relevance gates what we keep. These rows are not added to the interventional headline.

raw 14 · after dedupe 14 · already on CT.gov 0 · kept 0 · parent 0 · uncertain 14 · dropped 0 · fetched 2026-07-30

Source notes: ictrp: Error: ICTRP public search unavailable (WHO portal is SPA-only; SOAP needs partnership). Tried: https://apps.who.int/tri

No secondary-registry studies passed dual-model relevance for this condition name (after dedupe).

Uncertain / not reviewed (14)

Where to find support

Condition-specific patient organisations, when Orphanet lists them, are on the disease’s Orphanet page. We also link umbrella groups that support undiagnosed and ultra-rare families.

Orphanet entry for Malignant tumor of fallopian tubes — check Associations / patient organisations on that page.

India — NPRD

Last verified 2026-07-26

This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.

Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.

How we counted this

Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored on the overview but are not added to the query string.

"Malignant tumor of fallopian tubes" OR "Malignant tumor of the fallopian tubes" OR "Cancer of fallopian tubes" OR "Cancer of the fallopian tubes" OR "Malignant tubal tumor" OR "Tubal cancer" OR "cancer of fallopian tube" OR "cancer of the fallopian tube" OR "fallopian tube cancer" OR "fallopian tube malignant neoplasm" OR "fallopian tube malignant tumor" OR "fallopian tube malignant tumour" OR "malignant fallopian tube neoplasm" OR "malignant fallopian tube tumor" OR "malignant fallopian tube tumour" OR "malignant neoplasm of fallopian tube" OR "malignant neoplasm of the fallopian tube" OR "malignant neoplasm of uterine tube" OR "malignant neoplasm of the uterine tube" OR "malignant tubal tumour" OR "malignant tumor of fallopian tube" OR "malignant tumor of the fallopian tube" OR "malignant tumour of fallopian tubes" OR "malignant tumour of the fallopian tubes" OR "malignant tumour of the fallopian tube" OR "malignant tumour of fallopian tube" OR "neoplasm, fallopian tube, malignant" OR "tumor, fallopian tube, malignant"

Run this search on Europe PMC

ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):

"Malignant tumor of fallopian tubes" OR "Malignant tumor of the fallopian tubes" OR "Cancer of fallopian tubes" OR "Cancer of the fallopian tubes" OR "Malignant tubal tumor" OR "Tubal cancer" OR "cancer of fallopian tube" OR "cancer of the fallopian tube" OR "fallopian tube cancer" OR "fallopian tube malignant neoplasm" OR "fallopian tube malignant tumor" OR "fallopian tube malignant tumour" OR "malignant fallopian tube neoplasm" OR "malignant fallopian tube tumor" OR "malignant fallopian tube tumour" OR "malignant neoplasm of fallopian tube" OR "malignant neoplasm of the fallopian tube" OR "malignant neoplasm of uterine tube" OR "malignant neoplasm of the uterine tube" OR "malignant tubal tumour" OR "malignant tumor of fallopian tube" OR "malignant tumor of the fallopian tube" OR "malignant tumour of fallopian tubes" OR "malignant tumour of the fallopian tubes" OR "malignant tumour of the fallopian tube" OR "malignant tumour of fallopian tube" OR "neoplasm, fallopian tube, malignant" OR "tumor, fallopian tube, malignant"

Interventional trials matched via: phrase (mesh = registered under a MeSH descriptor no name phrase would catch; recall-expansion = gene / selected parent terms used only for trials).

Study-type breakdown: 561 interventional · 59 observational · 0 expanded access. Only interventional studies enter the trial headline.

Query health: ok — strategies attempted: phrase; with hits: phrase

Run this search on ClinicalTrials.gov

Confidence reasoning

  • Preferred label is multi-word and distinctive
  • No synonyms dropped by stoplist
  • No label/synonym collisions with other diseases in this corpus

Ingested 2026-07-27T09:04:15.261Z