ORPHA:180129
Partial septate uterus
Also known as: Subtotal septate uterus · Uterus subseptus
Publications
125
54th percentile
Trials
0
Interventional, condition-specific
Researchers
600
Distinct authors in sample
Gene link
—
Readiness
2/6
Stages with a signal
Clinical definition (Orphanet)
Partial septate uterus is a rare, non-syndromic uterovaginal characterized by a uterus that has a longitudinal septum which extends from the uterine fundus and does not reach the internal cervical os (variable lengths and widths may be observed). Although frequently asymptomatic, an increased risk of poor reproductive outcome has been observed. Urinary tract abnormalities are very rarely associated.
Cross-references
Joined from Mondo / Orphanet. MeSH labels may enter searches; UMLS / OMIM / NCIT are stored for reference.
- MONDO:0015841
- UMLS:C0266401
Additional Mondo synonyms (2)
subtotal septate uterus · uterus subseptus
Research stages
Trial readiness signals
Where this condition sits on an open-data research pipeline — not how close a treatment is, and not medical advice. Empty stages often mean “not in these databases under this Mondo ID,” not “impossible.”
2/6 stages with a signal
No specific-condition interventional trial, but broader-category trials exist — discuss eligibility with a clinician.
- Gene identifiedNot found
No GenCC disease–gene assertion in this build
- LiteraturePresent
125 matched papers (78 in last 10 years) Source
- Phenotype characterisedNot found
No HPO disease–phenotype associations via Monarch for these Mondo IDs
- Animal modelNot found
No Alliance genotype “model of” associations via Monarch for these Mondo IDs
- Orphan designationNot found
No FDA or EMA orphan-drug designation matched this disease via UMLS or preferred name Source
- Interventional trialPartial
None under the specific name; 4 for broader category septate uterus
Biology
Genes and phenotypes
Gene–disease validity from GenCC, plus phenotypes and animal models joined from Monarch Initiative via Mondo ID — not a clinical diagnosis aid.
Do we know what causes it?
Not yet — the cause hasn't been pinned down in GenCC.
No strong gene–disease assertion joined for this Orphanet entity.
Phenotypes (Monarch / HPO)
None returned for this Mondo ID. That often means “not linked under this ID,” not “no clinical features.”
Animal models (Monarch / Alliance)
None returned for this Mondo ID. Empty here is not proof that no model organism work exists under another name or gene.
Monarch fetch 2026-07-29
Therapies
Designations, candidates, and chemicals
FDA OOPD and EMA orphan designations, Open Targets clinical candidates, and CTD chemical associations via MyDisease.info. These never change the interventional-trial headline.
Orphan designation (FDA · EMA)
No designation matched this disease via UMLS or preferred name on the FDA OOPD mirror or EMA orphan register. Absence here is not proof that none exists under another wording.
Open Targets candidates
No drugs or clinical candidates returned for this Mondo ID on Open Targets.
CTD chemicals (MyDisease.info)
No CTD chemical associations returned for this Mondo ID.
Literature
Is anyone studying this?
125
125 papers have ever been published on this condition (under this name). For scale, breast cancer has over 700,000. Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=3967) is 59.
125 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 59 (publications denominator n=3967).
78 in the last 10 years · high confidence · 54th percentile (publications denominator)
Phrase hits: 125 · MeSH hits: 0
Who's working on it?
600
Distinct author names in 125 sampled papers — named people below.
Who's working on it?
No interventional trial matched this name; these authors publish on it in the sampled literature — a practical starting point for contact.
- 01Campo R5 papers · 2016
Congenital Uterine Malformations (CONUTA) Common ESHRE/ESGE Working Group and Invited Experts, Leuven, Belgium.
Papers in Europe PMC - 02Grimbizis GF5 papers · 2022
Congenital Uterine Anomalies (CONUTA) common ESHRE-ESGE Working Group, ESGE Central Office, Diestsevest 43/0001, 3000 Leuven, Belgium ; First Department of Obstetrics & Gynecology, Aristotle University of Thessaloniki, Tsimiski 51 Street, 54623 Thessaloniki, Greece.
Papers in Europe PMC - 03Brucker S4 papers · 2021
Congenital Uterine Malformations (CONUTA) Common ESHRE/ESGE Working Group and Invited Experts, Leuven, Belgium.
Papers in Europe PMC - 04Gergolet M4 papers · 2016
Congenital Uterine Malformations (CONUTA) Common ESHRE/ESGE Working Group and Invited Experts, Leuven, Belgium.
Papers in Europe PMC - 05Gianaroli L4 papers · 2016
Congenital Uterine Malformations (CONUTA) Common ESHRE/ESGE Working Group and Invited Experts, Leuven, Belgium.
Papers in Europe PMC - 06Gordts S4 papers · 2016
Congenital Uterine Malformations (CONUTA) Common ESHRE/ESGE Working Group and Invited Experts, Leuven, Belgium.
Papers in Europe PMC - 07Liu R4 papers · 2024
Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Papers in Europe PMC - 08De Angelis C3 papers · 2016
Congenital Uterine Malformations (CONUTA) Common ESHRE/ESGE Working Group and Invited Experts, Leuven, Belgium.
Papers in Europe PMC - 09Di Spiezio Sardo A3 papers · 2016
Congenital Uterine Malformations (CONUTA) Common ESHRE/ESGE Working Group and Invited Experts, Leuven, Belgium.
Papers in Europe PMC - 10Li TC3 papers · 2016
Congenital Uterine Malformations (CONUTA) Common ESHRE/ESGE Working Group and Invited Experts, Leuven, Belgium.
Papers in Europe PMC
Clinical research
Is a treatment being tested?
0
interventional trials for this specific condition
No interventional trial testing a treatment matched this specific condition name on ClinicalTrials.gov (observational studies and pan-disease registries are listed separately when present). 4 trials are registered for septate uterus, the broader category — shown separately because they may or may not enrol this specific subtype.
Data as of 11 September 2026 · last trial check 11 September 2026
No matched interventional trials. This is true for 77.2% of diseases in the trials denominator (5501 of 7126). Here are the researchers publishing on it.
high confidence · 38.6th percentile (trials denominator)
Recruiting interventional trials
From the matched ClinicalTrials.gov set
No interventional trial testing a treatment was found for this specific condition name on ClinicalTrials.gov.
4 interventional trials matched septate uterus, the broader category — listed below. Those studies are not counted in the condition-specific total.
Broader category: septate uterus
4
Interventional trials for the parent category, exclusive of NCT IDs already counted above. Eligibility for this subtype is not guaranteed.
Worth raising with a clinician. How we count trials.
Other registries (secondary)
Broader net from EU CTIS, ISRCTN, and ICTRP when available — deduped against ClinicalTrials.gov IDs already counted above. Dual-model LLM relevance gates what we keep. These rows are not added to the interventional headline.
raw 0 · after dedupe 0 · already on CT.gov 0 · kept 0 · parent 0 · uncertain 0 · dropped 0 · fetched 2026-07-30
Source notes: ictrp: Error: ICTRP public search unavailable (WHO portal is SPA-only; SOAP needs partnership). Tried: https://apps.who.int/tri
No secondary-registry studies passed dual-model relevance for this condition name (after dedupe).
Where to find support
Condition-specific patient organisations, when Orphanet lists them, are on the disease’s Orphanet page. We also link umbrella groups that support undiagnosed and ultra-rare families.
Orphanet entry for Partial septate uterus — check Associations / patient organisations on that page.
India — NPRD
Last verified 2026-07-26This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.
Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.
How we counted this
Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored on the overview but are not added to the query string.
"Partial septate uterus" OR "Subtotal septate uterus" OR "Uterus subseptus"
ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):
"Partial septate uterus" OR "Subtotal septate uterus" OR "Uterus subseptus"
Study-type breakdown: 0 interventional · 0 observational · 0 expanded access. Only interventional studies enter the trial headline.
Parent-category trials query:
"septate uterus"
Query health: ok — strategies attempted: phrase; with hits: phrase
Run this search on ClinicalTrials.gov
Confidence reasoning
- Preferred label is multi-word and distinctive
- No synonyms dropped by stoplist
- No label/synonym collisions with other diseases in this corpus
Ingested 2026-07-27T08:57:55.113Z