ORPHA:1560
Cysticercosis
Publications
10,916
Trials
6
Interventional, condition-specific
Researchers
1,054
Distinct authors in sample
Gene link
—
Readiness
2/6
Stages with a signal
Clinical definition (Orphanet)
Cysticercosis is a parasitic infectious disease characterized by cyst formation in the target tissue of Taenia solium (tapeworm) parasite larvae ingested via the feces of a human with a tapeworm (human-to-human fecal-oral transmission) leading to variable clinical manifestations in muscle, the brain, spinal cord, and eyes. Infection of muscle tissue is generally asymptomatic. Cyst development in the brain and spinal cord is known as neurocysticercosis (NCC) and may cause and headache. NCC can follow a serious course and may be life-threatening. Severe cases of cysticercosis are treated with albendazole and anti-inflammatory drugs.
How rare: How common this is has not been clearly measured.
Cross-references
Joined from Mondo / Orphanet. MeSH labels may enter searches; UMLS / OMIM / NCIT are stored for reference.
- MONDO:0015484
- MeSH:D003551
- UMLS:C0010678
- NCIT:C34520
Additional Mondo synonyms (3)
tapeworm infection: [intestinal taenia solium] or [pork] · tapeworm infection: intestinal taenia solum · tapeworm infection: pork
Research stages
Trial readiness signals
Where this condition sits on an open-data research pipeline — not how close a treatment is, and not medical advice. Empty stages often mean “not in these databases under this Mondo ID,” not “impossible.”
2/6 stages with a signal
An interventional trial matched this condition name on ClinicalTrials.gov — see trials below.
- Gene identifiedNot found
No GenCC disease–gene assertion in this build
- LiteraturePresent
10,916 matched papers (3,552 in last 10 years) Source
- Phenotype characterisedNot checked
Not yet enriched from Monarch / HPO
- Animal modelNot checked
Not yet enriched from Monarch / Alliance
- Orphan designationNot checked
FDA/EMA orphan-drug designation not enriched yet
- Interventional trialPresent
6 matched on ClinicalTrials.gov (1 recruiting in sample)
Biology
Genes and phenotypes
Gene–disease validity from GenCC, plus phenotypes and animal models joined from Monarch Initiative via Mondo ID — not a clinical diagnosis aid.
Do we know what causes it?
Not yet — the cause hasn't been pinned down in GenCC.
No strong gene–disease assertion joined for this Orphanet entity.
Phenotypes (Monarch / HPO)
Not enriched in this build — Monarch phenotype joins were not run for this record.
Animal models (Monarch / Alliance)
Not enriched in this build.
Literature
Is anyone studying this?
10,916
10,916 papers — among the better-studied rare conditions, though still a fraction of common-disease literature (breast cancer: over 700,000). Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=5449) is 41.
10,916 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 41 (publications denominator n=5449).
3,552 in the last 10 years · low confidence
Phrase hits: 10,916 · MeSH hits: 0
Who's working on it?
1,054
Distinct author names in 200 sampled papers — named people below.
Who's working on it?
People publishing on this condition (sampled Europe PMC records). Affiliation is the most recent found in that sample.
- 01Garcia HH9 papers · 2026
Department of Microbiology, School of Sciences, Universidad Peruana Cayetano Heredia, Av. Honorio Delgado 430, San Martin de Porres, Lima, Peru; Center of Global Health, Universidad Peruana Cayetano Heredia, Lima 15202, Peru; Cysticercosis Unit, Department of Transmissible Diseases, Instituto Nacional de Ciencias Neurologicas, Jr. Ancash 1217, Barrios Altos, Lima, Peru. Electronic address: hgarcia1@jhu.edu.
Papers in Europe PMC - 02Winkler AS9 papers · 2025
Department of Neurology and Center for Global Health, School of Medicine and Health, Technical University Munich, Munich, Germany.
Papers in Europe PMC - 03Bustos JA8 papers · 2026
Department of Microbiology, School of Sciences, Universidad Peruana Cayetano Heredia, Av. Honorio Delgado 430, San Martin de Porres, Lima, Peru; Center of Global Health, Universidad Peruana Cayetano Heredia, Lima 15202, Peru. Electronic address: javier.bustos.p@upch.pe.
Papers in Europe PMC - 04Sharma R8 papers · 2025Papers in Europe PMC
- 05Gabriël S7 papers · 2026
Department of Translational Physiology, Infectiology and Public Health, Faculty of Veterinary Medicine, Ghent University, 9820 Merelbeke, Belgium. Electronic address: sarah.gabriel@ugent.be.
Papers in Europe PMC - 06Arroyo G4 papers · 2026
Parasitological Diagnostic Laboratory, Infectious Diseases Laboratory Research-LID, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru.
Papers in Europe PMC - 07Mwape KE4 papers · 2026
Department of Clinical studies, School of Veterinary Medicine, University of Zambia, Lusaka, Zambia.
Papers in Europe PMC - 08Ngwili N4 papers · 2026
Health program, International Livestock Research Institute, Nairobi, Kenya. n.ngwili@cgiar.org.
Papers in Europe PMC - 09Stelzle D4 papers · 2025
Department of Neurology and Center for Global Health, School of Medicine and Health, Technical University Munich, Munich, Germany.
Papers in Europe PMC - 10Thomas LF4 papers · 2026
Health program, International Livestock Research Institute, Nairobi, Kenya.
Papers in Europe PMC
Clinical research
Is a treatment being tested?
6
interventional trials for this specific condition
6 interventional trials matched this specific condition name; 1 currently recruiting in our sample.
Data as of 27 July 2026
6 interventional trials — more than 73% of diseases in the trials denominator have none at all (5114 of 7003; this disease is at the 89th percentile).
low confidence · 89th percentile (trials denominator)
Recruiting interventional trials
From the matched ClinicalTrials.gov set
6 interventional trials matched after quoted-phrase search and title/condition post-filter.
- NCT06565507·NOT YET RECRUITING·Oxfendazole in Mild Parenchymal Brain Cysticercosis
Conditions: Brain Cysticercosis·Matched via name phrase
Observational and natural-history studies
4 observational studies match this condition. These do not test a treatment and are not counted in the interventional-trial headline, but they are genuine research: natural-history work often defines the endpoints needed for a future rare-disease trial, and families may be able to enroll.
Recruiting or not-yet-recruiting
- NCT00001205·RECRUITING·Natural History of Treated Neurocysticercosis and Long-Term Outcomes
Conditions: Cysticercosis · Neurocysticercosis·Matched via name phrase
Where to find support
We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:
India — NPRD
Last verified 2026-07-26This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.
Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.
How we counted this
Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored on the overview but are not added to the query string.
"Cysticercosis" OR "tapeworm infection: [intestinal taenia solium] or [pork]" OR "tapeworm infection: intestinal taenia solum" OR "tapeworm infection: pork"
ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):
"Cysticercosis" OR "tapeworm infection: [intestinal taenia solium] or [pork]" OR "tapeworm infection: intestinal taenia solum" OR "tapeworm infection: pork"
Interventional trials matched via: phrase (mesh = registered under a MeSH descriptor no name phrase would catch; recall-expansion = gene / selected parent terms used only for trials).
Study-type breakdown: 6 interventional · 4 observational · 0 expanded access. Only interventional studies enter the trial headline.
Query health: ok — strategies attempted: phrase; with hits: phrase
Run this search on ClinicalTrials.gov
Confidence reasoning
- Preferred label is short or not clearly distinctive
- No synonyms dropped by stoplist
- No label/synonym collisions with other diseases in this corpus
- Publication count (10916) is extremely high with unknown/missing prevalence — treat as possible over-matching, not proven research intensity
Ingested 2026-07-26T17:43:58.438Z