ORPHA:1201
Small bowel atresia
Also known as: Atresia of small bowel · Atresia of small intestine · Jejunal atresia · Jejunoileal atresia · SBA · Small intestinal atresia
Publications
1,920
92.9th percentile
Trials
0
Interventional, condition-specific
Researchers
1,107
Distinct authors in sample
Gene link
—
Readiness
1/6
Stages with a signal
Clinical definition (Orphanet)
A rare, defect of the small intestine characterized by disruption in the normal small intestine continuity, resulting in intestinal obstruction. The may be classified in four different types of small bowel atresia (SBA) based on the anatomical obstruction.
How rare: 1-9 / 100 000 — about one to nine people per hundred thousand.
Cross-references
Joined from Mondo / Orphanet. MeSH labels may enter searches; UMLS / OMIM / NCIT are stored for reference.
- MONDO:0009476
- MeSH:C538260
- OMIM:243600
- UMLS:C0266172
- NCIT:C98828
Additional Mondo synonyms (8)
Jejunal Atresia · apple peel syndrome · atresia of the small intestine · congenital small intestine atresia · intestinal atresia type IIIb · jejunal atresia · small intestinal atresia · small intestine atresia
Research stages
Trial readiness signals
Where this condition sits on an open-data research pipeline — not how close a treatment is, and not medical advice. Empty stages often mean “not in these databases under this Mondo ID,” not “impossible.”
1/6 stages with a signal
Research-stage checklist from open sources (GenCC, literature, Monarch when enriched, ClinicalTrials.gov). Not a prognosis or care recommendation.
- Gene identifiedNot found
No GenCC disease–gene assertion in this build
- LiteraturePresent
1,920 matched papers (906 in last 10 years) Source
- Phenotype characterisedNot checked
Not yet enriched from Monarch / HPO
- Animal modelNot checked
Not yet enriched from Monarch / Alliance
- Orphan designationNot checked
FDA/EMA orphan-drug designation not enriched yet
- Interventional trialNot found
No matched interventional trial under our ClinicalTrials.gov rules
Biology
Genes and phenotypes
Gene–disease validity from GenCC, plus phenotypes and animal models joined from Monarch Initiative via Mondo ID — not a clinical diagnosis aid.
Do we know what causes it?
Not yet — the cause hasn't been pinned down in GenCC.
No strong gene–disease assertion joined for this Orphanet entity.
Phenotypes (Monarch / HPO)
Not enriched in this build — Monarch phenotype joins were not run for this record.
Animal models (Monarch / Alliance)
Not enriched in this build.
Literature
Is anyone studying this?
1,920
1,920 papers have been published on this condition. That is a real research literature — still far smaller than common diseases (breast cancer: over 700,000 papers). Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=5449) is 41.
1,920 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 41 (publications denominator n=5449).
906 in the last 10 years · medium confidence · 92.9th percentile (publications denominator)
Phrase hits: 1,920 · MeSH hits: 0
Who's working on it?
1,107
Distinct author names in 200 sampled papers — named people below.
Who's working on it?
No interventional trial matched this name; these authors publish on it in the sampled literature — a practical starting point for contact.
- 01Msuya D4 papers · 2026
Department of General Surgery, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.
Papers in Europe PMC - 02Chen D3 papers · 2026
Department of Ultrasound, Guangdong Women and Children's Hospital, Guangzhou, China.
Papers in Europe PMC - 03Hu S3 papers · 2025
Department of Neonatal Surgery, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China.
Papers in Europe PMC - 04Lodhia J3 papers · 2024
Department of General Surgery, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.
Papers in Europe PMC - 05Pakarinen MP3 papers · 2026
Department of Pediatric Surgery, The New Children's Hospital, University of Helsinki, Stenbäckinkatu 9, 00029 HUS, Helsinki, Finland; Department of Women's and Children's Health, Karoliska Institutet, Stockholm, Sweden.
Papers in Europe PMC - 06
- 07Tsuruno Y3 papers · 2026
Department of Pediatric Surgery, Himeji Red Cross Hospital, 1-12-1, Shimoteno, Himeji, Hyogo, 670-8540, Japan.
Papers in Europe PMC - 08Ahmad H2 papers · 2026
Department of Pediatric Surgery, Children's Hospital of Orange County, University of California Irvine School of Medicine, CA, USA.
Papers in Europe PMC - 09Aly H2 papers · 2024
Department of Neonatology, Cleveland Clinic Children's, Cleveland, Ohio.
Papers in Europe PMC - 10Badillo A2 papers · 2026
Department of Colorectal and Pelvic Reconstruction, Children's National, Washington, District of Columbia, United States.
Papers in Europe PMC
Clinical research
Is a treatment being tested?
0
interventional trials for this specific condition
No interventional trial testing a treatment matched this specific condition name on ClinicalTrials.gov (observational studies and pan-disease registries are listed separately when present).
Data as of 27 July 2026
No matched interventional trials. This is true for 73% of diseases in the trials denominator (5114 of 7003). Here are the researchers publishing on it.
medium confidence · 36.5th percentile (trials denominator)
Recruiting interventional trials
From the matched ClinicalTrials.gov set
No interventional trial testing a treatment was found for this specific condition name on ClinicalTrials.gov.
See who's working on it — people publishing on this disease are often the practical next contact when no trial is listed.
Where to find support
We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:
India — NPRD
Last verified 2026-07-26This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.
Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.
How we counted this
Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored on the overview but are not added to the query string.
"Small bowel atresia" OR "Atresia of small bowel" OR "Atresia of the small bowel" OR "Atresia of small intestine" OR "Atresia of the small intestine" OR "Jejunal atresia" OR "Jejunoileal atresia" OR "Small intestinal atresia" OR "apple peel syndrome" OR "congenital small intestine atresia" OR "intestinal atresia type IIIb" OR "small intestine atresia"
ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):
"Small bowel atresia" OR "Atresia of small bowel" OR "Atresia of the small bowel" OR "Atresia of small intestine" OR "Atresia of the small intestine" OR "Jejunal atresia" OR "Jejunoileal atresia" OR "Small intestinal atresia" OR "apple peel syndrome" OR "congenital small intestine atresia" OR "intestinal atresia type IIIb" OR "small intestine atresia"
Study-type breakdown: 0 interventional · 0 observational · 0 expanded access. Only interventional studies enter the trial headline.
Query health: ok — strategies attempted: phrase; with hits: phrase
Run this search on ClinicalTrials.gov
Synonyms dropped by stoplist: SBA
Confidence reasoning
- Preferred label is multi-word and distinctive
- 1 synonym(s) dropped by stoplist (may under-count)
- No label/synonym collisions with other diseases in this corpus
Ingested 2026-07-26T16:40:54.409Z