RARE DISEASERESEARCH ATLAS

ORPHA:1160

Chylous ascites

low confidence

Clinical definition (Orphanet)

Chylous ascites is a rare form of ascites caused by accumulation of lymph in the peritoneal cavity, usually due to intra-abdominal malignancy, liver cirrhosis or abdominal surgery complications, and present with painless but abdominal distension, dyspnea and weight gain.

How rare: How common this is has not been clearly measured.

Orphanet entry

Is anyone studying this?

3,913

3,913 papers have been published on this condition. That is a real research literature — still far smaller than common diseases (breast cancer: over 700,000 papers). Median papers in the last 10 years for a rare disease in this dataset (publications denominator n=183) is 38.

3,913 papers since the earliest indexed year in this search — median last-10-year count for a rare disease in this dataset is 38 (publications denominator n=183).

1,801 in the last 10 years · low confidence

Is a treatment being tested?

1

trials for this specific condition

1 interventional trial matched this specific condition name; none in our sample are currently recruiting.

Data as of 26 July 2026

1 interventional trial — more than 59.2% of diseases in the trials denominator have none at all (151 of 255; this disease is at the 65.3th percentile).

low confidence · 65.3th percentile (trials denominator)

Do we know what causes it?

Not yet — the cause hasn't been pinned down in GenCC.

No strong gene–disease assertion joined for this Orphanet entity.

Who's working on it?

1,131

Distinct author names in 200 sampled papers — named people below.

Who's working on it?

People publishing on this condition (sampled Europe PMC records). Affiliation is the most recent found in that sample.

  1. 01
    Kato M10 papers · 2026

    Department of Pediatric Surgery, Keio University School of Medicine, Tokyo, Japan.

    Papers in Europe PMC
  2. 02
    Takahashi M7 papers · 2026

    Department of Medical Oncology, Tohoku University Hospital, Sendai 980-8547, Japan.

    Papers in Europe PMC
  3. 03
    Aoki Y6 papers · 2026

    Department of Gynecologic Oncology, Cancer Institute Hospital of the Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto, Tokyo 135-8550 Japan.

    Papers in Europe PMC
  4. 04
    Kamata M6 papers · 2026

    Department of Gynecologic Oncology, Cancer Institute Hospital of the Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto, Tokyo 135-8550 Japan.

    Papers in Europe PMC
  5. 05
    Nakajima Y6 papers · 2026

    Division of Pediatric Endocrinology, Metabolism and Nephrology, Children's Medical Center, Osaka City General Hospital, Osaka 534-0021, Japan.

    Papers in Europe PMC
  6. 06
    Ogawa K6 papers · 2026

    Department of Pediatric Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.

    Papers in Europe PMC
  7. 07
    Sasaki S6 papers · 2026

    Surgery, Tobata Kyoritsu Hospital, Kitakyusyu, JPN.

    Papers in Europe PMC
  8. 08
    Tanaka K6 papers · 2026

    Department of General and Gastroenterological Surgery, Showa Medical University Fujigaoka Hospital, Yokohama, Kanagawa, Japan.

    Papers in Europe PMC
  9. 09
    Akita S5 papers · 2026

    Department of Plastic Surgery, Tamaki Aozora Hospital, Tokushima City, Japan.

    Papers in Europe PMC
  10. 10
    Arai Y5 papers · 2026

    Department of Pediatric Surgery, Niigata University, Niigata City, Japan.

    Papers in Europe PMC

Recruiting interventional trials

Trials testing a treatment from the matched ClinicalTrials.gov set

1 interventional trials matched after quoted-phrase search and title/condition post-filter.

No currently recruiting studies in the matched set. Open the same search on ClinicalTrials.gov.

Where to find support

We do not yet link condition-specific patient organisations. These umbrella groups support undiagnosed and ultra-rare families:

India — NPRD

Last verified 2026-07-26

This ORPHAcode is not on our curated NPRD list (direct or Mondo-parent match). That does not decide clinical eligibility; families in India should ask a notified Centre of Excellence about current coverage.

Hand-curated for this project. ORPHAcode mappings are best-effort and may be incomplete or imprecise for umbrella categories. Parent (Mondo) matches mean the policy lists a broader category — confirm eligibility with a Centre of Excellence. Financial entitlements summarised from public policy statements and may change. This is not official government guidance.

How we counted this

Europe PMC query (preferred label + any corrected label + Orphanet and Mondo exact synonyms, stoplisted; unioned with resolved MeSH labels when available). UMLS / OMIM / NCIT cross-references are stored below but are not added to the query string.

"Chylous ascites"

Run this search on Europe PMC

MeSH descriptor terms unioned into the query: Chylous Ascites

ClinicalTrials.gov query (quoted phrases + MeSH via query.cond, plus recall-expansion terms when used):

"Chylous ascites"

Interventional trials matched via: both (mesh = registered under a MeSH descriptor no name phrase would catch; recall-expansion = gene / selected parent terms used only for trials).

Study-type breakdown: 1 interventional · 0 observational · 0 expanded access. Only interventional studies enter the trial headline.

Cross-references (from Mondo): MESH:D002915 OMIM:208300 UMLS:C0008732 NCIT:C34482

Query health: ok — strategies attempted: phrase, mesh; with hits: phrase, mesh

Run this search on ClinicalTrials.gov

Confidence reasoning

  • Preferred label is multi-word and distinctive
  • No synonyms dropped by stoplist
  • No label/synonym collisions with other diseases in this corpus
  • Publication count (3913) is extremely high with unknown/missing prevalence — treat as possible over-matching, not proven research intensity

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